Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1348273..1348781 Replicon chromosome
Accession NZ_AP025472
Organism Vibrio cortegadensis strain CECT 7227

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCV39_RS06440 Protein ID WP_113796438.1
Coordinates 1348273..1348533 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OCV39_RS06445 Protein ID WP_113796440.1
Coordinates 1348530..1348781 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV39_RS06410 1343781..1344089 + 309 WP_261889322.1 transposase -
OCV39_RS06415 1344086..1344937 + 852 WP_261889306.1 IS3 family transposase -
OCV39_RS06420 1345681..1346160 + 480 WP_261889323.1 DM13 domain-containing protein -
OCV39_RS06425 1346288..1346605 - 318 WP_171757578.1 CcdB family protein -
OCV39_RS06430 1346605..1346850 - 246 WP_261889324.1 type II toxin-antitoxin system CcdA family antitoxin -
OCV39_RS06435 1347688..1348137 + 450 WP_261889325.1 hypothetical protein -
OCV39_RS06440 1348273..1348533 - 261 WP_113796438.1 Txe/YoeB family addiction module toxin Toxin
OCV39_RS06445 1348530..1348781 - 252 WP_113796440.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OCV39_RS06450 1348980..1349372 + 393 WP_261889326.1 NUDIX domain-containing protein -
OCV39_RS06455 1349526..1350158 + 633 WP_261889327.1 type B chloramphenicol O-acetyltransferase -
OCV39_RS06460 1350738..1351694 - 957 WP_261889315.1 IS110 family transposase -
OCV39_RS06465 1352226..1352474 + 249 WP_029203587.1 DUF3297 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1200955..1350280 149325
- flank IS/Tn - - 1350738..1351694 956


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10376.92 Da        Isoelectric Point: 10.0297

>T40312 WP_113796438.1 NZ_AP025472:c1348533-1348273 [Vibrio cortegadensis]
MKLTFATKAWNDYLYWQTTDKKILKRINTLIKDIQRSPYEGIGKPEPLKHGLSGYWSRRINDEHRIVYKYQEDTILIAQV
RYHYGT

Download         Length: 261 bp

>T40312 NZ_AP025472:c1348533-1348273 [Vibrio cortegadensis]
ATGAAACTAACTTTTGCAACCAAAGCTTGGAATGATTATCTGTACTGGCAAACCACAGATAAAAAAATTCTAAAGCGCAT
AAATACTTTGATCAAAGATATCCAGCGCTCGCCCTATGAAGGGATTGGGAAGCCTGAACCTCTAAAGCATGGACTTTCTG
GGTATTGGTCTCGACGTATAAACGATGAACACCGGATTGTGTACAAGTATCAAGAGGACACGATCCTCATTGCTCAAGTT
AGATACCATTACGGCACATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9238.50 Da        Isoelectric Point: 4.6234

>AT40312 WP_113796440.1 NZ_AP025472:c1348781-1348530 [Vibrio cortegadensis]
MDAISYTAARANLASTMHKVCNDHAPVIITRKSEEPVVMISLEDYKAMEETTYLLRSPANARNLLDSISELESGKGEVRE
LIE

Download         Length: 252 bp

>AT40312 NZ_AP025472:c1348781-1348530 [Vibrio cortegadensis]
ATGGACGCTATTAGTTACACTGCCGCTCGTGCAAATTTAGCAAGTACTATGCATAAAGTTTGTAACGACCACGCACCTGT
TATTATTACACGCAAAAGTGAAGAGCCTGTTGTAATGATTTCGCTCGAAGACTACAAAGCGATGGAAGAAACAACTTACT
TACTCCGCTCTCCTGCTAATGCTAGAAATTTACTTGATTCAATATCAGAATTAGAATCAGGCAAAGGCGAAGTACGAGAA
CTAATTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References