Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1289648..1290414 Replicon chromosome
Accession NZ_AP025472
Organism Vibrio cortegadensis strain CECT 7227

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OCV39_RS06010 Protein ID WP_261889266.1
Coordinates 1289648..1290145 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OCV39_RS06015 Protein ID WP_261889267.1
Coordinates 1290142..1290414 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV39_RS05990 1284684..1285193 + 510 WP_261889263.1 ClbS/DfsB family four-helix bundle protein -
OCV39_RS05995 1285332..1286657 + 1326 WP_261889264.1 hypothetical protein -
OCV39_RS06000 1286787..1287269 + 483 WP_136996049.1 MazG-related protein -
OCV39_RS06005 1287406..1288368 + 963 WP_261889265.1 DUF2971 domain-containing protein -
OCV39_RS06010 1289648..1290145 - 498 WP_261889266.1 GNAT family N-acetyltransferase Toxin
OCV39_RS06015 1290142..1290414 - 273 WP_261889267.1 DUF1778 domain-containing protein Antitoxin
OCV39_RS06020 1291109..1291906 + 798 WP_261889268.1 hypothetical protein -
OCV39_RS06025 1292043..1292489 + 447 WP_171757633.1 hypothetical protein -
OCV39_RS06030 1292639..1293532 + 894 WP_261889269.1 hypothetical protein -
OCV39_RS06035 1293738..1294070 + 333 WP_023603298.1 type II toxin-antitoxin system RelE/ParE family toxin -
OCV39_RS06040 1294057..1294371 + 315 WP_012550279.1 type II toxin-antitoxin system MqsA family antitoxin -
OCV39_RS06045 1294506..1295009 + 504 WP_261889270.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1200955..1350280 149325


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-151)

Antitoxin

Vibrio phage ICP1, Orf50

(7-86)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18491.06 Da        Isoelectric Point: 8.0487

>T40306 WP_261889266.1 NZ_AP025472:c1290145-1289648 [Vibrio cortegadensis]
MMNTVLLEKAKHDRNRFNCGSEALNNYLKVMASQQAKKDNTRTFVLEDNNDSSHVIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDEHYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKDFYERYGFQAFQDTENKLFITISDV
RANLG

Download         Length: 498 bp

>T40306 NZ_AP025472:c1290145-1289648 [Vibrio cortegadensis]
ATGATGAACACGGTACTACTAGAAAAAGCAAAACATGATAGAAATCGGTTCAACTGCGGTAGTGAAGCTCTTAATAACTA
CCTGAAAGTAATGGCGAGTCAGCAAGCAAAGAAAGACAACACCAGAACTTTCGTTTTAGAAGATAACAACGATAGCTCGC
ATGTCATTGGTTTTTATACACTAACAATGACACCAATCGATTTGAAGGCTTTACCCGACAAGCTACAGAAAAAACACCAA
TCATCGACTTCTGGTGGTCTAATTGCCCGTTTAGCAGTCGATGAACACTACAAAGGTAAAGGCTTTGGCGAGTGGCTCCT
TATTGATGCACTTAGAAAGCTACTAGCAGCCAGTGATAGCGTTGCATTCCCTGTAGTCATTGTTGACGCCAAAGACGGTG
CAAAAGACTTCTACGAGCGATATGGATTCCAAGCGTTTCAAGATACAGAAAATAAACTCTTTATTACTATTTCTGATGTA
AGAGCGAATTTAGGCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9816.39 Da        Isoelectric Point: 9.8133

>AT40306 WP_261889267.1 NZ_AP025472:c1290414-1290142 [Vibrio cortegadensis]
MATTLPRITARVDVDTQHLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQVDAMLLMDALDRPATINSKLKT
ASERYESKTQ

Download         Length: 273 bp

>AT40306 NZ_AP025472:c1290414-1290142 [Vibrio cortegadensis]
ATGGCGACTACTTTACCCCGCATCACTGCTAGAGTTGATGTCGATACACAACACTTACTGACAAAAGCGGCGGCAATTGC
TGGCATGTCTAGTATTAACTCATTTGTTCTAAGTGCTGCTATCGAAAAAGCCAAACAAGTTATTGAACGTGAACAAGCCC
TTAAACTTAGCCAAGTTGATGCTATGTTACTTATGGATGCTTTAGACCGTCCTGCAACAATCAACTCAAAATTGAAAACT
GCTTCTGAACGTTACGAGAGCAAAACTCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References