Detailed information of TA system TA040303

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 1244889..1245436
• Replicon: chromosome
• Accession: NZ_AP025472
• Organism: Vibrio cortegadensis strain CECT 7227

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCV39_RS05750
• Protein ID: WP_261889232.1
• Coordinates: 1245134..1245436 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCV39_RS05745
• Protein ID: WP_261889231.1
• Coordinates: 1244889..1245146 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCV39_RS05710	1240191..1240481	-	291	WP_261889223.1	type II toxin-antitoxin system RelE/ParE family toxin	-
OCV39_RS05715	1240490..1240732	-	243	WP_261889224.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
OCV39_RS05720	1241537..1241896	+	360	WP_261889228.1	GFA family protein	-
OCV39_RS05725	1242037..1242684	+	648	WP_261889225.1	HAD family phosphatase	-
OCV39_RS05730	1242832..1243341	+	510	WP_261889221.1	hypothetical protein	-
OCV39_RS05735	1243487..1243891	+	405	WP_261889229.1	GFA family protein	-
OCV39_RS05740	1244029..1244691	+	663	WP_261889230.1	hypothetical protein	-
OCV39_RS05745	1244889..1245146	+	258	WP_261889231.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCV39_RS05750	1245134..1245436	+	303	WP_261889232.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCV39_RS05755	1247867..1248268	-	402	WP_261889233.1	YkgJ family cysteine cluster protein	-
OCV39_RS05760	1248552..1248875	-	324	WP_261889234.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	1200955..1350280	149325

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11672.53 Da
• Isoelectric Point: 4.8951

>T40303 WP_261889232.1 NZ_AP025472:1245134-1245436 [Vibrio cortegadensis]
MAEIIWTEPALSDLNDIAEYIALENVVSAKQLVQTIFSKVERLESFPESGRIPPELEHLSYREVVVNPCRVFYKQDADKV
FILFVMRAERDLRKFLLSKQ

Nucleotide

• Length: 303 bp

>T40303 NZ_AP025472:1245134-1245436 [Vibrio cortegadensis]
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCCGACCTCAATGATATCGCTGAATATATCGCACTTGAAAATGTCGT
TTCAGCAAAGCAATTGGTTCAAACGATTTTCTCTAAAGTTGAGCGTCTAGAGAGTTTTCCGGAATCAGGGCGTATTCCAC
CTGAATTAGAACATTTAAGTTACCGTGAGGTTGTTGTTAATCCATGTCGTGTATTCTATAAACAAGACGCAGACAAAGTA
TTTATTCTGTTTGTTATGCGTGCCGAAAGAGATTTGCGTAAGTTCCTGTTGAGTAAACAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9619.14 Da
• Isoelectric Point: 7.3177

>AT40303 WP_261889231.1 NZ_AP025472:1244889-1245146 [Vibrio cortegadensis]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLSILEGIARGERALADGKVVNHEAAKDKM
SKWLK

Nucleotide

• Length: 258 bp

>AT40303 NZ_AP025472:1244889-1245146 [Vibrio cortegadensis]
ATGAAAGTAGAATTAGTCACATCACTCAAGCGTCAAGCAACTAAGATCCTAGCCGATCTACACGACACTAAAGAACCAGT
ATTAATTACCGAGCACGGTAAACCATCTGCATATTTGATCGATGTTGATGATTACGAGTTTATGCAAAACCGTTTGTCAA
TTCTTGAGGGTATTGCGCGAGGCGAACGCGCACTAGCTGATGGCAAAGTGGTTAATCACGAAGCAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA