Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1202798..1203308 Replicon chromosome
Accession NZ_AP025472
Organism Vibrio cortegadensis strain CECT 7227

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCV39_RS05490 Protein ID WP_113795376.1
Coordinates 1203045..1203308 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OCV39_RS05485 Protein ID WP_113795377.1
Coordinates 1202798..1203052 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV39_RS05465 1199643..1200194 + 552 WP_084654942.1 translation initiation factor IF-3 -
OCV39_RS05470 1200300..1200494 + 195 WP_017052549.1 50S ribosomal protein L35 -
OCV39_RS05475 1200534..1200887 + 354 WP_017052550.1 50S ribosomal protein L20 -
OCV39_RS05480 1200955..1201917 - 963 WP_113795334.1 integron integrase -
OCV39_RS05485 1202798..1203052 + 255 WP_113795377.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OCV39_RS05490 1203045..1203308 + 264 WP_113795376.1 Txe/YoeB family addiction module toxin Toxin
OCV39_RS05495 1203473..1204333 + 861 WP_261889195.1 DUF3265 domain-containing protein -
OCV39_RS05500 1204479..1204904 + 426 WP_261889196.1 GNAT family N-acetyltransferase -
OCV39_RS05505 1205043..1205864 + 822 WP_261889197.1 HNH endonuclease signature motif containing protein -
OCV39_RS05510 1206003..1206905 + 903 WP_261889198.1 hypothetical protein -
OCV39_RS05515 1207014..1207745 + 732 WP_261889199.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1200955..1350280 149325


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10295.69 Da        Isoelectric Point: 8.8578

>T40298 WP_113795376.1 NZ_AP025472:1203045-1203308 [Vibrio cortegadensis]
MSNRLLAWTDEAWDSYVYWQGQDKKTLKRINKLINDVKRSPFDGIGKPEPLKENLTGFWSRRIDDSNRLVYAIDDGVITI
ISCRYHY

Download         Length: 264 bp

>T40298 NZ_AP025472:1203045-1203308 [Vibrio cortegadensis]
ATGAGTAATCGTCTATTAGCTTGGACCGATGAGGCTTGGGATAGTTATGTTTATTGGCAGGGGCAGGATAAAAAAACGCT
TAAGCGAATTAACAAGCTCATTAATGATGTTAAACGTTCGCCTTTTGATGGTATCGGTAAACCGGAGCCATTAAAGGAAA
ATTTAACAGGTTTTTGGTCTCGCCGAATTGATGATTCAAATCGTCTTGTTTATGCGATTGATGATGGAGTGATTACAATT
ATTTCGTGCAGATATCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9455.72 Da        Isoelectric Point: 4.7377

>AT40298 WP_113795377.1 NZ_AP025472:1202798-1203052 [Vibrio cortegadensis]
MRIVSFTEARNGLKAVLDGVVNDADATVITRRDSEDAVVMSLDYYNSLMETIYLMRSPANAEHLNKSIAQYKAGKVIQRD
IFDE

Download         Length: 255 bp

>AT40298 NZ_AP025472:1202798-1203052 [Vibrio cortegadensis]
ATGAGAATTGTCTCTTTCACAGAAGCTAGAAATGGTTTGAAAGCCGTTCTTGATGGTGTAGTTAATGATGCGGATGCAAC
AGTAATCACTCGTAGAGATTCTGAAGATGCGGTAGTAATGTCGCTGGATTATTACAATAGCTTAATGGAAACCATTTATT
TAATGCGCTCTCCTGCTAATGCAGAGCATTTAAATAAATCTATCGCTCAATACAAAGCGGGTAAAGTAATACAGCGAGAT
ATTTTCGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References