Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1804713..1805272 Replicon chromosome
Accession NZ_AP025471
Organism Vibrio coralliirubri strain DSM 27495

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCV20_RS24770 Protein ID WP_048610373.1
Coordinates 1804713..1804991 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCV20_RS24775 Protein ID WP_086774055.1
Coordinates 1804988..1805272 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV20_RS24750 1800381..1800779 - 399 WP_086774059.1 DUF1090 domain-containing protein -
OCV20_RS24755 1800933..1802465 - 1533 WP_086774058.1 SgrR family transcriptional regulator -
OCV20_RS24760 1802476..1803486 - 1011 WP_086774057.1 Gfo/Idh/MocA family oxidoreductase -
OCV20_RS24765 1803600..1804499 - 900 WP_086774056.1 homocysteine S-methyltransferase family protein -
OCV20_RS24770 1804713..1804991 - 279 WP_048610373.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
OCV20_RS24775 1804988..1805272 - 285 WP_086774055.1 damage-inducible protein J Antitoxin
OCV20_RS24780 1805457..1806158 + 702 WP_086774054.1 lipoate--protein ligase -
OCV20_RS24785 1806215..1806616 - 402 WP_086774053.1 SAM-dependent methyltransferase -
OCV20_RS24790 1806650..1807540 - 891 WP_017087615.1 DMT family transporter -
OCV20_RS24795 1807660..1808244 + 585 WP_086774052.1 TetR/AcrR family transcriptional regulator -
OCV20_RS24800 1808363..1809238 - 876 WP_086774051.1 radical SAM protein -
OCV20_RS24805 1809451..1810272 - 822 WP_086774050.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10949.63 Da        Isoelectric Point: 4.2397

>T40297 WP_048610373.1 NZ_AP025471:c1804991-1804713 [Vibrio coralliirubri]
MILWEEESLNDRERIFEFIYDFNPDAAENADNLIETKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWIEGDVIRIM
RVLHQKQKFPMD

Download         Length: 279 bp

>T40297 NZ_AP025471:c1804991-1804713 [Vibrio coralliirubri]
ATGATTTTATGGGAAGAAGAATCACTCAATGATCGTGAAAGGATCTTTGAGTTTATCTATGACTTCAACCCTGATGCGGC
AGAGAACGCTGACAACCTCATTGAAACAAAAGTAGAAAACTTGCTTGAGCAGCCTCTAATGGGTGTACAGAGAGACGGCA
TTCGTGGACGATTACTTATAATTCCTGAGATTTCAATGATCGTCTCCTATTGGATAGAAGGCGACGTTATCCGAATTATG
CGCGTACTCCACCAGAAACAAAAGTTCCCAATGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11086.39 Da        Isoelectric Point: 7.1702

>AT40297 WP_086774055.1 NZ_AP025471:c1805272-1804988 [Vibrio coralliirubri]
MDTRIQFRIDEETKRLAQQMAESQGRTLSGACRELTEQLAEQQRQTLSHDAWLTEQVNLAFEKFDSGESVFVEHQTAKFR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT40297 NZ_AP025471:c1805272-1804988 [Vibrio coralliirubri]
ATGGACACTAGAATTCAATTTCGTATTGATGAAGAAACAAAACGCCTAGCTCAACAGATGGCTGAGAGCCAAGGTCGTAC
ACTGAGTGGTGCTTGCCGTGAGCTTACTGAGCAACTCGCTGAGCAACAAAGACAGACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAGAATCCGTTTTCGTTGAACACCAAACTGCTAAATTTCGA
ATGGAAGAACGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References