Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 599322..599869 Replicon chromosome
Accession NZ_AP025471
Organism Vibrio coralliirubri strain DSM 27495

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCV20_RS19150 Protein ID WP_086775905.1
Coordinates 599322..599624 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7W4GJX8
Locus tag OCV20_RS19155 Protein ID WP_017093596.1
Coordinates 599612..599869 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV20_RS19120 594746..595714 - 969 WP_086774347.1 tyrosine-type recombinase/integrase -
OCV20_RS19125 595815..596225 + 411 WP_086774348.1 DUF3319 domain-containing protein -
OCV20_RS19130 596188..596499 + 312 WP_008221404.1 stress response translation initiation inhibitor YciH -
OCV20_RS19135 596802..598148 + 1347 WP_108721727.1 ISNCY family transposase -
OCV20_RS19140 598472..598894 + 423 WP_086775907.1 phage protein -
OCV20_RS19145 599011..599268 - 258 WP_086775906.1 hypothetical protein -
OCV20_RS19150 599322..599624 - 303 WP_086775905.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCV20_RS19155 599612..599869 - 258 WP_017093596.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCV20_RS19160 599980..600519 - 540 WP_076652154.1 hypothetical protein -
OCV20_RS19165 600516..601526 - 1011 WP_086775904.1 hypothetical protein -
OCV20_RS19170 601631..601978 - 348 WP_086775903.1 hypothetical protein -
OCV20_RS19175 602106..602468 - 363 WP_086775902.1 hypothetical protein -
OCV20_RS19180 602979..603389 - 411 WP_086775900.1 hypothetical protein -
OCV20_RS19185 603386..603814 - 429 WP_086775899.1 M15 family metallopeptidase -
OCV20_RS19190 603862..604302 - 441 WP_086775898.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11737.57 Da        Isoelectric Point: 5.2080

>T40295 WP_086775905.1 NZ_AP025471:c599624-599322 [Vibrio coralliirubri]
MAEVIWSEPALSDLNDIAEYIALENLVAAKQLVQNVFGKVERLVDFPESGRRPPELEHLNYREVVVNPCRVFYKQEADKV
YILFVMRAERDLRRFLLSKQ

Download         Length: 303 bp

>T40295 NZ_AP025471:c599624-599322 [Vibrio coralliirubri]
ATGGCTGAAGTGATTTGGAGTGAGCCCGCGTTATCTGACCTTAACGATATCGCGGAATACATTGCTCTTGAAAATTTGGT
CGCAGCCAAACAACTCGTTCAAAACGTCTTCGGCAAAGTCGAACGCCTCGTAGACTTTCCTGAGTCTGGACGTCGGCCTC
CCGAGCTCGAGCATCTCAATTATCGTGAAGTCGTGGTGAATCCGTGTCGGGTTTTTTACAAACAAGAAGCTGACAAGGTC
TACATCCTGTTTGTGATGCGTGCGGAGCGAGATTTGCGTCGATTTTTACTGAGTAAACAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9679.15 Da        Isoelectric Point: 6.7273

>AT40295 WP_017093596.1 NZ_AP025471:c599869-599612 [Vibrio coralliirubri]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYQFMQNRLAILEGIARGERAISEGKELSHDEAKDKM
SKWLK

Download         Length: 258 bp

>AT40295 NZ_AP025471:c599869-599612 [Vibrio coralliirubri]
ATGAAAGTCGAGCTCGTTACTTCCCTTAAGCGTCAAGCGACCAAAATCCTTGCCGACCTACACGACACCAAAGAGCCCGT
GTTGATCACTGAGCATGGCAAACCTTCTGCGTATCTCGTGGATGTTGACGATTACCAGTTTATGCAAAACCGCTTGGCTA
TCCTTGAAGGGATCGCACGTGGTGAGCGTGCCATTTCTGAAGGCAAGGAACTGAGTCATGACGAAGCTAAAGACAAGATG
TCAAAATGGCTGAAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7W4GJX8

References