Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 547303..547865 Replicon chromosome
Accession NZ_AP025458
Organism Vibrio artabrorum strain CECT 7226

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OCU36_RS02485 Protein ID WP_261838895.1
Coordinates 547303..547605 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OCU36_RS02490 Protein ID WP_261838896.1
Coordinates 547605..547865 (-) Length 87 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU36_RS02455 543121..543435 + 315 WP_261838891.1 L-rhamnose mutarotase -
OCU36_RS02460 543432..544232 + 801 WP_261838892.1 rhamnulose-1-phosphate aldolase -
OCU36_RS02465 544241..545383 + 1143 WP_261838893.1 iron-containing alcohol dehydrogenase -
OCU36_RS02470 545559..546353 + 795 WP_261838894.1 helix-turn-helix domain-containing protein -
OCU36_RS02475 546403..546642 - 240 Protein_449 Tn3 family transposase -
OCU36_RS02480 547059..547148 + 90 Protein_450 resolvase -
OCU36_RS02485 547303..547605 - 303 WP_261838895.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU36_RS02490 547605..547865 - 261 WP_261838896.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU36_RS02495 548056..548738 - 683 Protein_453 IS6 family transposase -
OCU36_RS02500 548930..549706 + 777 WP_261838897.1 peroxide stress protein YaaA -
OCU36_RS02505 549819..551084 - 1266 WP_261838898.1 ATP-dependent RNA helicase SrmB -
OCU36_RS02510 551192..551920 - 729 WP_261838899.1 methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11686.44 Da        Isoelectric Point: 9.3087

>T40286 WP_261838895.1 NZ_AP025458:c547605-547303 [Vibrio artabrorum]
MTHYKLSSAAQSDLIEIRRYTLELWGQTQWTTYFSEFKQSMELLANNQLLGIGVSELGQNYFRFPLKHHVIYYIQKQEHI
VIAAVLGKHMSPAKHFSQLS

Download         Length: 303 bp

>T40286 NZ_AP025458:c547605-547303 [Vibrio artabrorum]
ATGACGCACTATAAGCTTTCTTCTGCAGCGCAATCAGATCTCATTGAGATTCGTCGCTATACATTAGAGCTATGGGGGCA
AACACAATGGACAACTTATTTTTCAGAGTTCAAGCAATCCATGGAATTACTAGCGAACAACCAACTGCTTGGCATAGGAG
TTTCTGAACTGGGCCAAAATTACTTCCGGTTTCCTTTAAAGCACCATGTGATTTATTACATCCAAAAACAAGAGCACATC
GTTATTGCAGCCGTTCTTGGTAAGCACATGTCTCCGGCCAAGCACTTTTCACAACTCTCTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9616.02 Da        Isoelectric Point: 4.4091

>AT40286 WP_261838896.1 NZ_AP025458:c547865-547605 [Vibrio artabrorum]
MQSLTANTAKTKFGDLLMKVQREPVQINKNGSPVAVMMSCEEYKQLEALKLMVVKSRFEQAEADVLSDNLVDGDDFMNAL
DQGKFD

Download         Length: 261 bp

>AT40286 NZ_AP025458:c547865-547605 [Vibrio artabrorum]
ATGCAATCACTTACTGCTAATACAGCTAAAACCAAATTTGGTGACTTACTGATGAAGGTTCAACGTGAACCTGTACAAAT
CAATAAGAACGGTTCACCCGTTGCGGTGATGATGTCTTGTGAAGAATATAAACAACTTGAAGCATTGAAATTGATGGTGG
TGAAATCGCGCTTCGAACAAGCAGAGGCCGATGTTCTATCAGATAACCTAGTCGACGGTGACGATTTCATGAATGCACTT
GACCAAGGTAAGTTTGATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References