Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 219932..220497 Replicon chromosome
Accession NZ_AP025458
Organism Vibrio artabrorum strain CECT 7226

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCU36_RS01045 Protein ID WP_261838665.1
Coordinates 220210..220497 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCU36_RS01040 Protein ID WP_261838664.1
Coordinates 219932..220213 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU36_RS01010 215123..216028 + 906 WP_261838659.1 ROK family protein -
OCU36_RS01015 216594..216839 + 246 WP_261838660.1 Rpn family recombination-promoting nuclease/putative transposase -
OCU36_RS01020 216811..217479 + 669 WP_261838661.1 Rpn family recombination-promoting nuclease/putative transposase -
OCU36_RS01025 217583..218473 - 891 WP_261838662.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
OCU36_RS01030 218488..219012 - 525 WP_261838663.1 hypothetical protein -
OCU36_RS01035 219134..219715 - 582 Protein_190 ISAs1 family transposase -
OCU36_RS01040 219932..220213 + 282 WP_261838664.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU36_RS01045 220210..220497 + 288 WP_261838665.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU36_RS01050 220559..221140 - 582 WP_261838666.1 hypothetical protein -
OCU36_RS01055 221137..222299 - 1163 Protein_194 site-specific integrase -
OCU36_RS01060 222722..223951 - 1230 WP_261838667.1 hypothetical protein -
OCU36_RS01065 223948..225348 - 1401 WP_261838668.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-72)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10979.51 Da        Isoelectric Point: 4.8254

>T40285 WP_261838665.1 NZ_AP025458:220210-220497 [Vibrio artabrorum]
MKVIWSPLAQEKLGDTAEFIALDNPVAAENWVNEIFDKTELLSSMPEMGRTVSELPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQTLTESDV

Download         Length: 288 bp

>T40285 NZ_AP025458:220210-220497 [Vibrio artabrorum]
ATGAAAGTAATTTGGTCACCTTTGGCGCAAGAAAAGCTAGGTGACACCGCTGAATTTATCGCTTTGGACAACCCTGTTGC
TGCTGAAAATTGGGTGAATGAAATCTTTGATAAAACGGAACTTTTAAGCAGTATGCCTGAAATGGGGCGTACGGTGTCTG
AGTTACCCCATACAAACTATCGTGAAATCATATTTGGGCATTACCGCATCATATATAGTCTAAGTCACGAAATCAGAGTT
CTTACTGTGAGAAACTGTCGTCAAACACTCACGGAAAGTGACGTGTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10480.95 Da        Isoelectric Point: 5.1768

>AT40285 WP_261838664.1 NZ_AP025458:219932-220213 [Vibrio artabrorum]
MSRIHFDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEIRTAEAQVASDLGVSN
EDARAQVLGRIKR

Download         Length: 282 bp

>AT40285 NZ_AP025458:219932-220213 [Vibrio artabrorum]
ATGAGTCGTATTCACTTTGATCAAGATATTCAGCCTTTGTCTGAATTTCGCGCTGGCGTAACGTCATTTATCAAGCAAAT
CAACGAGACTCGTAGACCACTTGTTATCACTCAACGTGGTAAAGGTGTCGCTGTGGTTCTAGACGTTGCCGAATATGAAG
CAATGCAAGAGAAAATTGAGTTACTAGAAGAAATACGAACAGCGGAAGCCCAGGTAGCTTCTGACTTAGGCGTTTCTAAC
GAAGATGCACGAGCTCAAGTTCTAGGGCGTATTAAGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References