Detailed information of TA system TA040285

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 219932..220497
• Replicon: chromosome
• Accession: NZ_AP025458
• Organism: Vibrio artabrorum strain CECT 7226

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCU36_RS01045
• Protein ID: WP_261838665.1
• Coordinates: 220210..220497 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCU36_RS01040
• Protein ID: WP_261838664.1
• Coordinates: 219932..220213 (+)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU36_RS01010	215123..216028	+	906	WP_261838659.1	ROK family protein	-
OCU36_RS01015	216594..216839	+	246	WP_261838660.1	Rpn family recombination-promoting nuclease/putative transposase	-
OCU36_RS01020	216811..217479	+	669	WP_261838661.1	Rpn family recombination-promoting nuclease/putative transposase	-
OCU36_RS01025	217583..218473	-	891	WP_261838662.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
OCU36_RS01030	218488..219012	-	525	WP_261838663.1	hypothetical protein	-
OCU36_RS01035	219134..219715	-	582	Protein_190	ISAs1 family transposase	-
OCU36_RS01040	219932..220213	+	282	WP_261838664.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCU36_RS01045	220210..220497	+	288	WP_261838665.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCU36_RS01050	220559..221140	-	582	WP_261838666.1	hypothetical protein	-
OCU36_RS01055	221137..222299	-	1163	Protein_194	site-specific integrase	-
OCU36_RS01060	222722..223951	-	1230	WP_261838667.1	hypothetical protein	-
OCU36_RS01065	223948..225348	-	1401	WP_261838668.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-72)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10979.51 Da
• Isoelectric Point: 4.8254

>T40285 WP_261838665.1 NZ_AP025458:220210-220497 [Vibrio artabrorum]
MKVIWSPLAQEKLGDTAEFIALDNPVAAENWVNEIFDKTELLSSMPEMGRTVSELPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQTLTESDV

Nucleotide

• Length: 288 bp

>T40285 NZ_AP025458:220210-220497 [Vibrio artabrorum]
ATGAAAGTAATTTGGTCACCTTTGGCGCAAGAAAAGCTAGGTGACACCGCTGAATTTATCGCTTTGGACAACCCTGTTGC
TGCTGAAAATTGGGTGAATGAAATCTTTGATAAAACGGAACTTTTAAGCAGTATGCCTGAAATGGGGCGTACGGTGTCTG
AGTTACCCCATACAAACTATCGTGAAATCATATTTGGGCATTACCGCATCATATATAGTCTAAGTCACGAAATCAGAGTT
CTTACTGTGAGAAACTGTCGTCAAACACTCACGGAAAGTGACGTGTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10480.95 Da
• Isoelectric Point: 5.1768

>AT40285 WP_261838664.1 NZ_AP025458:219932-220213 [Vibrio artabrorum]
MSRIHFDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEIRTAEAQVASDLGVSN
EDARAQVLGRIKR

Nucleotide

• Length: 282 bp

>AT40285 NZ_AP025458:219932-220213 [Vibrio artabrorum]
ATGAGTCGTATTCACTTTGATCAAGATATTCAGCCTTTGTCTGAATTTCGCGCTGGCGTAACGTCATTTATCAAGCAAAT
CAACGAGACTCGTAGACCACTTGTTATCACTCAACGTGGTAAAGGTGTCGCTGTGGTTCTAGACGTTGCCGAATATGAAG
CAATGCAAGAGAAAATTGAGTTACTAGAAGAAATACGAACAGCGGAAGCCCAGGTAGCTTCTGACTTAGGCGTTTCTAAC
GAAGATGCACGAGCTCAAGTTCTAGGGCGTATTAAGCGATGA