Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 217583..219012 Replicon chromosome
Accession NZ_AP025458
Organism Vibrio artabrorum strain CECT 7226

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag OCU36_RS01025 Protein ID WP_261838662.1
Coordinates 217583..218473 (-) Length 297 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag OCU36_RS01030 Protein ID WP_261838663.1
Coordinates 218488..219012 (-) Length 175 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU36_RS01005 213911..215095 + 1185 WP_261838658.1 mannose-6-phosphate isomerase, class I -
OCU36_RS01010 215123..216028 + 906 WP_261838659.1 ROK family protein -
OCU36_RS01015 216594..216839 + 246 WP_261838660.1 Rpn family recombination-promoting nuclease/putative transposase -
OCU36_RS01020 216811..217479 + 669 WP_261838661.1 Rpn family recombination-promoting nuclease/putative transposase -
OCU36_RS01025 217583..218473 - 891 WP_261838662.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
OCU36_RS01030 218488..219012 - 525 WP_261838663.1 hypothetical protein Antitoxin
OCU36_RS01035 219134..219715 - 582 Protein_190 ISAs1 family transposase -
OCU36_RS01040 219932..220213 + 282 WP_261838664.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OCU36_RS01045 220210..220497 + 288 WP_261838665.1 type II toxin-antitoxin system RelE/ParE family toxin -
OCU36_RS01050 220559..221140 - 582 WP_261838666.1 hypothetical protein -
OCU36_RS01055 221137..222299 - 1163 Protein_194 site-specific integrase -
OCU36_RS01060 222722..223951 - 1230 WP_261838667.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(42-265)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 297 a.a.        Molecular weight: 34274.14 Da        Isoelectric Point: 6.1739

>T40284 WP_261838662.1 NZ_AP025458:c218473-217583 [Vibrio artabrorum]
MLKQKIDEILKRNPELAPVVEVIEKEILHHDILHVMTEHGALQRLTFIGGTSLRLCYNSSRLSEDLDFNGGHDFKPSMFD
GLEDEIQSFLQKKYEIPVYVNKPSPDKQGNTSSWKISIEKEPNRADLPRQKMHIDVCALPSFDLTNRVPINHYGIDTPTE
GMLIRCQTMDEILADKFIALAYRARRIKPRDVWDIVWLNQRGIEVNNQLINNKLEARDKERDDFLIALGRQMKNLTENDV
VKADFNSEMSRFVPQTLQAKTLDVPEYWDYVRETISNMGKRVSQPSSPTNKFDMSL

Download         Length: 891 bp

>T40284 NZ_AP025458:c218473-217583 [Vibrio artabrorum]
ATGCTAAAACAAAAAATAGACGAAATTCTAAAACGTAACCCTGAGTTAGCACCCGTTGTTGAAGTGATCGAAAAAGAGAT
ACTTCATCATGATATTTTGCATGTCATGACAGAACACGGGGCACTACAAAGACTCACCTTCATTGGCGGTACCTCACTAC
GCCTTTGCTACAACAGTTCTCGGTTATCTGAAGACTTAGACTTTAATGGTGGTCATGATTTTAAGCCATCGATGTTTGAT
GGGCTTGAGGATGAAATACAGAGCTTTTTGCAAAAGAAATATGAAATACCTGTATACGTCAATAAACCTAGCCCAGACAA
GCAAGGGAATACATCATCGTGGAAAATCAGCATCGAGAAAGAACCAAACCGTGCTGATCTGCCCAGACAGAAAATGCACA
TTGATGTTTGTGCTTTACCCTCTTTCGATTTGACAAATCGAGTGCCTATAAATCATTACGGAATCGACACACCAACAGAA
GGTATGCTGATCCGTTGCCAAACAATGGACGAAATTTTAGCTGATAAATTCATTGCTTTAGCATACAGGGCAAGGCGAAT
TAAGCCCCGTGATGTGTGGGATATTGTGTGGCTAAATCAAAGAGGCATTGAGGTCAATAACCAGTTAATCAACAACAAAC
TAGAGGCCCGTGACAAAGAACGTGATGACTTTTTGATTGCGCTGGGCAGGCAAATGAAAAACCTAACTGAAAATGATGTA
GTTAAGGCTGACTTCAACAGCGAGATGAGTCGATTTGTACCTCAAACATTGCAAGCAAAAACGCTTGATGTACCTGAGTA
TTGGGACTATGTGAGAGAAACAATCAGTAACATGGGTAAGAGAGTTTCACAACCAAGCTCACCCACAAATAAATTTGATA
TGAGCCTTTAG

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19956.15 Da        Isoelectric Point: 10.2066

>AT40284 WP_261838663.1 NZ_AP025458:c219012-218488 [Vibrio artabrorum]
VAKVEKLISAMAESSKFGKGVFSKAELAYLLNVEQTPRFNKFLYDCVKKGTINRIANGLFESTITPPNPRTAIYEVARKL
RPGYLNYISLESELSRTGEISQIIMDRLTLMTRGRSGTFKTRYGVVEFTHTKHKVSQLENDLFFDEEVKMYRAMPHRALA
DLKSCKRNLQMINH

Download         Length: 525 bp

>AT40284 NZ_AP025458:c219012-218488 [Vibrio artabrorum]
GTGGCTAAGGTAGAAAAACTAATTTCAGCTATGGCTGAATCAAGTAAATTTGGCAAAGGCGTATTCAGTAAGGCTGAACT
TGCCTACCTTCTCAATGTCGAACAAACACCCCGTTTTAACAAATTTCTGTACGACTGTGTTAAAAAAGGCACCATTAATC
GAATCGCTAATGGTCTTTTTGAAAGCACAATCACCCCTCCAAATCCCCGAACTGCAATATATGAAGTCGCCCGTAAATTA
AGGCCTGGCTACCTAAATTATATAAGTTTAGAGAGTGAATTATCACGTACTGGAGAGATATCTCAAATCATTATGGATCG
CCTGACTCTAATGACTCGGGGGCGAAGTGGGACATTTAAAACTCGCTACGGAGTGGTTGAGTTTACACATACTAAGCACA
AAGTATCACAGCTTGAAAATGACCTATTCTTCGACGAAGAGGTGAAAATGTATCGAGCTATGCCTCATCGAGCATTAGCC
GATTTAAAAAGCTGTAAACGAAACCTACAAATGATAAATCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References