Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 97885..98411 Replicon plasmid pTMTA97341
Accession NZ_AP025335
Organism Phytobacter diazotrophicus strain TA9734

Toxin (Protein)


Gene name relE Uniprot ID S1EXL1
Locus tag L6445_RS27930 Protein ID WP_000323025.1
Coordinates 98124..98411 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID J5W3H0
Locus tag L6445_RS27925 Protein ID WP_004196370.1
Coordinates 97885..98124 (+) Length 80 a.a.

Genomic Context

L6445_RS27895L6445_RS27900L6445_RS27925L6445_RS27930L6445_RS27940L6445_RS27950L6445_RS27955L6445_RS27960L6445_RS27965L6445_RS27890L6445_RS27905L6445_RS27910L6445_RS27915L6445_RS27920L6445_RS27945L6445_RS27970
Location: 93444..94421 (978 bp)
Type: Others
Protein ID: WP_004196334.1
Location: 94378..95754 (1377 bp)
Type: Others
Protein ID: WP_004196363.1
Location: 97885..98124 (240 bp)
Type: Antitoxin
Protein ID: WP_004196370.1
Location: 98124..98411 (288 bp)
Type: Toxin
Protein ID: WP_000323025.1
Location: 98516..98641 (126 bp)
Type: Others
Protein ID: WP_223540704.1
Location: 99667..100245 (579 bp)
Type: Others
Protein ID: WP_125125756.1
Location: 100317..100619 (303 bp)
Type: Others
Protein ID: WP_125125757.1
Location: 101345..101647 (303 bp)
Type: Others
Protein ID: WP_047368814.1
Location: 101661..102479 (819 bp)
Type: Others
Protein ID: WP_172600722.1
Location: 93222..93414 (193 bp)
Type: Others
Protein ID: Protein_102
Location: 95785..96474 (690 bp)
Type: Others
Protein ID: WP_004196322.1
Location: 96488..97225 (738 bp)
Type: Others
Protein ID: WP_008460272.1
Location: 97269..97634 (366 bp)
Type: Others
Protein ID: WP_009651956.1
Location: 97762..97860 (99 bp)
Type: Others
Protein ID: Protein_108
Location: 98846..99100 (255 bp)
Type: Others
Protein ID: WP_125125755.1
Location: 102496..103041 (546 bp)
Type: Others
Protein ID: WP_125125759.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
L6445_RS2789093222..93414-193Protein_102MFS transporter-
L6445_RS27895 (PDTA9734_55170)93444..94421+978WP_004196334.1chromate resistance protein-
L6445_RS27900 (PDTA9734_55180)94378..95754+1377WP_004196363.1chromate efflux transporter-
L6445_RS27905 (PDTA9734_55190)95785..96474-690WP_004196322.1hypothetical protein-
L6445_RS27910 (PDTA9734_55200)96488..97225-738WP_008460272.1HupE/UreJ family protein-
L6445_RS27915 (PDTA9734_55210)97269..97634-366WP_009651956.1hypothetical protein-
L6445_RS2792097762..97860-99Protein_108protein YdfV-
L6445_RS27925 (PDTA9734_55220)97885..98124+240WP_004196370.1type II toxin-antitoxin system antitoxin RelBAntitoxin
L6445_RS27930 (PDTA9734_55230)98124..98411+288WP_000323025.1type II toxin-antitoxin system mRNA interferase RelEToxin
L6445_RS27940 (PDTA9734_55240)98516..98641+126WP_223540704.1type I toxin-antitoxin system Hok family toxin-
L6445_RS27945 (PDTA9734_55250)98846..99100-255WP_125125755.1DUF2767 family protein-
L6445_RS27950 (PDTA9734_55260)99667..100245+579WP_125125756.1hypothetical protein-
L6445_RS27955 (PDTA9734_55270)100317..100619+303WP_125125757.1hypothetical protein-
L6445_RS27960 (PDTA9734_55280)101345..101647+303WP_047368814.1hypothetical protein-
L6445_RS27965 (PDTA9734_55290)101661..102479+819WP_172600722.1DUF932 domain-containing protein-
L6445_RS27970 (PDTA9734_55300)102496..103041-546WP_125125759.1lytic transglycosylase domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..174856174856


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11225.22 Da        Isoelectric Point: 10.1967

>T40272 WP_000323025.1 NZ_AP025335:98124-98411 [Phytobacter diazotrophicus]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL

Download         Length: 288 bp

>T40272 NZ_AP025335:98124-98411 [Phytobacter diazotrophicus]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9018.43 Da        Isoelectric Point: 4.3894

>AT40272 WP_004196370.1 NZ_AP025335:97885-98124 [Phytobacter diazotrophicus]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL

Download         Length: 240 bp

>AT40272 NZ_AP025335:97885-98124 [Phytobacter diazotrophicus]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
PDB4V7K
PDB4V7J
PDB4FXI
PDB4FXE
PDB2KC8
PDB4FXH
PDB2KC9

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A2J4QRH4

References