Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 5311305..5311968 Replicon chromosome
Accession NZ_AP025334
Organism Phytobacter diazotrophicus strain TA9734

Toxin (Protein)


Gene name tad Uniprot ID A0A348DL83
Locus tag L6445_RS25490 Protein ID WP_039077908.1
Coordinates 5311305..5311649 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID A0A348DL84
Locus tag L6445_RS25495 Protein ID WP_071194355.1
Coordinates 5311651..5311968 (+) Length 106 a.a.

Genomic Context

L6445_RS25475L6445_RS25490L6445_RS25495L6445_RS25505L6445_RS25515L6445_RS25470L6445_RS25480L6445_RS25485L6445_RS25500L6445_RS25510L6445_RS25520L6445_RS25525
Location: 5308447..5309430 (984 bp)
Type: Others
Protein ID: WP_039077906.1
Location: 5311305..5311649 (345 bp)
Type: Toxin
Protein ID: WP_039077908.1
Location: 5311651..5311968 (318 bp)
Type: Antitoxin
Protein ID: WP_071194355.1
Location: 5313599..5314114 (516 bp)
Type: Others
Protein ID: WP_039077912.1
Location: 5314529..5314717 (189 bp)
Type: Others
Protein ID: WP_071194358.1
Location: 5306982..5308388 (1407 bp)
Type: Others
Protein ID: WP_039077905.1
Location: 5309719..5309961 (243 bp)
Type: Others
Protein ID: WP_039077907.1
Location: 5310114..5311112 (999 bp)
Type: Others
Protein ID: WP_039077935.1
Location: 5312010..5313326 (1317 bp)
Type: Others
Protein ID: WP_039077910.1
Location: 5314222..5314431 (210 bp)
Type: Others
Protein ID: WP_039077936.1
Location: 5314692..5315306 (615 bp)
Type: Others
Protein ID: WP_039077914.1
Location: 5315415..5315783 (369 bp)
Type: Others
Protein ID: WP_079497650.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
L6445_RS25470 (5306982)5306982..5308388-1407WP_039077905.1replicative DNA helicase-
L6445_RS25475 (5308447)5308447..5309430+984WP_039077906.1quinone oxidoreductase-
L6445_RS25480 (5309719)5309719..5309961-243WP_039077907.1envelope stress response protein PspG-
L6445_RS25485 (5310114)5310114..5311112-999WP_039077935.1tRNA dihydrouridine(20/20a) synthase DusA-
L6445_RS25490 (5311305)5311305..5311649+345WP_039077908.1type II toxin-antitoxin system RelE/ParE family toxinToxin
L6445_RS25495 (5311651)5311651..5311968+318WP_071194355.1helix-turn-helix transcriptional regulatorAntitoxin
L6445_RS25500 (5312010)5312010..5313326-1317WP_039077910.1conjugal transfer protein TraF-
L6445_RS25505 (5313599)5313599..5314114+516WP_039077912.1zinc uptake transcriptional repressor Zur-
L6445_RS25510 (5314222)5314222..5314431-210WP_039077936.1CsbD family protein-
L6445_RS25515 (5314529)5314529..5314717+189WP_071194358.1hypothetical protein-
L6445_RS25520 (5314692)5314692..5315306-615WP_039077914.1transcriptional repressor LexA-
L6445_RS25525 (5315415)5315415..5315783-369WP_079497650.1diacylglycerol kinase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12655.46 Da        Isoelectric Point: 9.5820

>T40270 WP_039077908.1 NZ_AP025334:5311305-5311649 [Phytobacter diazotrophicus]
MKPLYWVGSSKKDLQSLPEDVQDVFGYALHLAQDGGKHPQAKPLKGFGGAGVLEVVEDYCTDTYRAVYTLKFRQAVYVLH
AFQKKSSSGMQTPKSDIEKIRERLKAAEAHARGA

Download         Length: 345 bp

>T40270 NZ_AP025334:5311305-5311649 [Phytobacter diazotrophicus]
ATGAAGCCACTGTATTGGGTGGGGAGCAGCAAAAAAGATCTTCAGTCTCTGCCGGAGGATGTTCAGGATGTTTTTGGTTA
TGCGTTGCATCTCGCACAAGACGGAGGTAAGCATCCCCAGGCAAAACCGTTAAAAGGATTTGGGGGCGCAGGTGTGCTGG
AGGTGGTCGAAGACTATTGCACCGATACTTATCGCGCGGTTTATACCCTGAAATTCAGACAGGCGGTCTATGTGCTACAT
GCATTTCAGAAGAAGTCGTCATCCGGTATGCAAACCCCCAAATCTGATATAGAAAAAATTCGAGAACGTCTTAAGGCAGC
AGAAGCCCATGCCAGAGGAGCATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11644.64 Da        Isoelectric Point: 11.1929

>AT40270 WP_071194355.1 NZ_AP025334:5311651-5311968 [Phytobacter diazotrophicus]
MSQNIDISSGNVYADIGLDNADEMQVKAQLATTIGNIIKSRRLTQVEAAKLLGMTQPRLSNMLRGQFRGISEVKMLECLT
RLGRDVQIVVGRPRRTPGRMKVVFA

Download         Length: 318 bp

>AT40270 NZ_AP025334:5311651-5311968 [Phytobacter diazotrophicus]
ATGAGCCAGAATATCGATATCAGCAGCGGCAATGTTTATGCCGACATTGGACTGGACAATGCGGATGAAATGCAGGTTAA
AGCGCAGCTTGCTACCACCATTGGCAATATCATTAAAAGTCGTCGTCTTACTCAGGTGGAGGCGGCAAAGTTATTGGGGA
TGACACAGCCCAGGCTATCAAATATGCTGCGCGGCCAATTTCGCGGCATAAGTGAAGTAAAAATGCTTGAATGTCTGACA
CGCTTAGGGCGCGATGTTCAAATTGTGGTTGGGCGCCCGCGCCGTACCCCGGGACGTATGAAGGTGGTTTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A348DL83

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A348DL84

References