Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 841299..842080 Replicon chromosome
Accession NZ_AP025334
Organism Phytobacter diazotrophicus strain TA9734

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag L6445_RS04005 Protein ID WP_125123871.1
Coordinates 841589..842080 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag L6445_RS04000 Protein ID WP_125123870.1
Coordinates 841299..841592 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6445_RS03990 (838295) 838295..838435 + 141 Protein_785 DUF1778 domain-containing protein -
L6445_RS03995 (838509) 838509..840698 - 2190 WP_125123869.1 TonB-dependent siderophore receptor -
L6445_RS04000 (841299) 841299..841592 + 294 WP_125123870.1 DUF1778 domain-containing protein Antitoxin
L6445_RS04005 (841589) 841589..842080 + 492 WP_125123871.1 GNAT family N-acetyltransferase Toxin
L6445_RS04010 (842145) 842145..842639 + 495 WP_232034376.1 hypothetical protein -
L6445_RS04015 (842829) 842829..843344 - 516 WP_125123872.1 hypothetical protein -
L6445_RS04020 (843499) 843499..844650 + 1152 Protein_791 IS3 family transposase -
L6445_RS04025 (845060) 845060..845656 - 597 WP_047749132.1 hypothetical protein -
L6445_RS04030 (845656) 845656..846000 - 345 WP_047749131.1 hypothetical protein -
L6445_RS04035 (846012) 846012..846560 - 549 WP_047749130.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17721.58 Da        Isoelectric Point: 7.2655

>T40255 WP_125123871.1 NZ_AP025334:841589-842080 [Phytobacter diazotrophicus]
MISAPEPLHTGHILTPFCCGMDSMDKWLKQRAMKNQVTGASRTFVCCGSDSNVQAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
ESI

Download         Length: 492 bp

>T40255 NZ_AP025334:841589-842080 [Phytobacter diazotrophicus]
ATGATCTCTGCTCCAGAACCGCTTCATACCGGGCATATTCTTACCCCGTTCTGTTGCGGCATGGATTCTATGGATAAGTG
GCTCAAACAACGGGCGATGAAAAATCAGGTCACTGGCGCATCGCGTACCTTTGTATGTTGCGGCAGCGATTCTAACGTAC
AGGCGTATTACTCGCTGGCGTCCAGCGCGGTAACGACCAACACCGCCCCCGGTCGCTTTCGTCGCAATATGCCCGATCCG
ATCCCGGTGGTGGTGCTGGGACGTCTGGCTGTGGATCAATCACTGCACGGGCAGGGCGTCGGGCGGGCGCTGGTTCGCGA
CGCCGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTGCACGCCCTGTCGGATGAAGCGC
GGGAGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTATTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10931.55 Da        Isoelectric Point: 8.6351

>AT40255 WP_125123870.1 NZ_AP025334:841299-841592 [Phytobacter diazotrophicus]
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYEEFLARLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT40255 NZ_AP025334:841299-841592 [Phytobacter diazotrophicus]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAATCTGCGCATCAGGCCCGCCGAGCGTGATCTTATCGA
CCGGGCAGCGAAGGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCCGCCCGCGCTGCCGCTGAGGAAGCGTTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATGAGGAGTTTCTGGCTCGTCTAGATCAGGCGCCTGCGCCTAAC
GCTGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References