Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 3772880..3773405 Replicon chromosome
Accession NZ_AP025281
Organism Aliamphritea hakodatensis strain PT3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PCI15_RS17235 Protein ID WP_271271167.1
Coordinates 3772880..3773155 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PCI15_RS17240 Protein ID WP_271271168.1
Coordinates 3773142..3773405 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCI15_RS17220 3769180..3769914 - 735 WP_271271164.1 NrdJb -
PCI15_RS17225 3769943..3772093 - 2151 WP_271271165.1 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase -
PCI15_RS17230 3772454..3772711 - 258 WP_271271166.1 hypothetical protein -
PCI15_RS17235 3772880..3773155 - 276 WP_271271167.1 Txe/YoeB family addiction module toxin Toxin
PCI15_RS17240 3773142..3773405 - 264 WP_271271168.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PCI15_RS17245 3773614..3774123 - 510 WP_271271169.1 N-acetyltransferase -
PCI15_RS17250 3774202..3775254 - 1053 WP_271271170.1 ribosome small subunit-dependent GTPase A -
PCI15_RS17255 3775519..3776001 - 483 WP_271271171.1 ester cyclase -
PCI15_RS17260 3776145..3776477 + 333 WP_271271172.1 helix-turn-helix domain-containing protein -
PCI15_RS17265 3776592..3777701 - 1110 WP_271271173.1 aminomethyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(12-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10719.39 Da        Isoelectric Point: 10.2605

>T40241 WP_271271167.1 NZ_AP025281:c3773155-3772880 [Aliamphritea hakodatensis]
MKKTSKLAVKFAGNAWEDYLYWQTHDKKQLKRINQLIGDIRRNPFAGLGKPEALKGDLAGFWSRRIDREHRLVYAILNDD
LVIVQCRYHYG

Download         Length: 276 bp

>T40241 NZ_AP025281:c3773155-3772880 [Aliamphritea hakodatensis]
ATGAAGAAGACTAGCAAACTGGCTGTAAAGTTTGCGGGGAATGCCTGGGAAGACTATCTGTATTGGCAGACTCACGATAA
AAAACAGCTTAAACGGATTAACCAGCTGATCGGTGATATACGCCGAAATCCTTTTGCCGGATTAGGGAAGCCAGAGGCAT
TAAAAGGTGATCTGGCCGGATTCTGGTCCCGGCGAATCGACCGGGAGCACCGGCTGGTATATGCCATTCTGAATGATGAT
CTGGTGATTGTTCAGTGCCGCTATCATTATGGCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9581.64 Da        Isoelectric Point: 4.0604

>AT40241 WP_271271168.1 NZ_AP025281:c3773405-3773142 [Aliamphritea hakodatensis]
MNVISYSDARASLKTVMDTVCDSHEATVVTRQKGDDVVILSKSDYDSVMETLYLLSSPANASRLLDAIAEVKAGQTQERE
LIQDEED

Download         Length: 264 bp

>AT40241 NZ_AP025281:c3773405-3773142 [Aliamphritea hakodatensis]
ATGAATGTAATCTCATACAGCGACGCCCGGGCCAGCTTAAAAACGGTGATGGATACCGTATGTGATTCCCACGAGGCGAC
TGTTGTTACCCGGCAAAAAGGTGATGACGTGGTTATTCTGTCCAAGAGTGATTATGACAGTGTTATGGAAACACTCTACC
TGCTGAGCAGCCCGGCTAACGCCAGCCGCTTGCTGGATGCGATCGCTGAAGTAAAAGCGGGCCAGACTCAGGAACGAGAG
CTAATTCAGGATGAAGAAGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References