Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 45100..45695 Replicon plasmid pPT65
Accession NZ_AP025261
Organism Paraburkholderia terrae strain KU-15

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PTKU15_RS47260 Protein ID WP_248558663.1
Coordinates 45405..45695 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PTKU15_RS47255 Protein ID WP_248558713.1
Coordinates 45100..45408 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTKU15_RS47240 (PTKU15_94590) 42707..43018 + 312 WP_248558661.1 DUF3892 domain-containing protein -
PTKU15_RS47245 (PTKU15_94600) 43039..44418 + 1380 WP_248558662.1 sigma-54 dependent transcriptional regulator -
PTKU15_RS47255 (PTKU15_94610) 45100..45408 + 309 WP_248558713.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PTKU15_RS47260 (PTKU15_94620) 45405..45695 + 291 WP_248558663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PTKU15_RS47265 (PTKU15_94630) 45783..45929 - 147 WP_248558664.1 hypothetical protein -
PTKU15_RS47270 (PTKU15_94650) 46487..46972 - 486 WP_248558665.1 MarR family transcriptional regulator -
PTKU15_RS47275 (PTKU15_94660) 46984..47967 - 984 WP_248558666.1 type II secretion system F family protein -
PTKU15_RS47280 (PTKU15_94670) 48008..48985 - 978 WP_248558714.1 type II secretion system F family protein -
PTKU15_RS47285 (PTKU15_94680) 49057..50340 - 1284 WP_248558715.1 CpaF family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..64706 64706
- flank IS/Tn - - 41982..42392 410


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-55)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11144.58 Da        Isoelectric Point: 4.6812

>T40204 WP_248558663.1 NZ_AP025261:45405-45695 [Paraburkholderia terrae]
MRLEWSVFALEDRDGIFDYIEEDSPRAAVVVDDRIRTQVRQLLQFPETGRLGRVEGTRELVISRTPYIAAYRITGDTVRI
LRVLHGAQQWPDEISD

Download         Length: 291 bp

>T40204 NZ_AP025261:45405-45695 [Paraburkholderia terrae]
TTGAGGCTTGAATGGTCGGTTTTCGCGCTGGAGGATCGGGACGGGATTTTCGATTACATCGAAGAAGACAGCCCACGCGC
TGCCGTTGTCGTGGATGATCGGATTCGCACCCAGGTCCGCCAGCTGCTCCAGTTCCCCGAGACGGGTCGCCTTGGTCGTG
TTGAGGGCACCCGCGAGCTGGTCATTAGCCGAACGCCGTACATCGCAGCGTATCGTATCACCGGCGACACCGTGCGCATC
CTGCGCGTGCTGCACGGCGCACAGCAATGGCCAGACGAGATATCGGACTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10873.42 Da        Isoelectric Point: 6.4688

>AT40204 WP_248558713.1 NZ_AP025261:45100-45408 [Paraburkholderia terrae]
MAASALVQTRIDPVLKERAAAVLDNMGLTVSDAVRILLTRVANEGALPFAFAADPAAHDAWFRAKVQEALADPRPAVPDD
EVEAHFAKRRAAALRKADKGDA

Download         Length: 309 bp

>AT40204 NZ_AP025261:45100-45408 [Paraburkholderia terrae]
ATGGCTGCGAGTGCATTGGTACAGACGCGCATCGATCCCGTGCTGAAAGAGCGCGCGGCCGCGGTGCTCGACAACATGGG
ACTGACCGTCTCGGATGCGGTGCGTATCCTGTTGACGCGCGTCGCGAACGAAGGTGCGCTGCCGTTCGCGTTCGCTGCCG
ATCCTGCCGCGCATGACGCATGGTTCCGCGCGAAGGTACAGGAGGCATTGGCCGATCCGCGGCCGGCTGTTCCGGACGAT
GAGGTCGAAGCCCATTTTGCCAAACGGCGCGCGGCGGCCCTTCGTAAAGCTGACAAGGGTGATGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References