Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 221856..222865 | Replicon | chromosome |
| Accession | NZ_AP025260 | ||
| Organism | Paraburkholderia terrae strain KU-15 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | PTKU15_RS44765 | Protein ID | WP_229517517.1 |
| Coordinates | 221856..222332 (-) | Length | 159 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | A0A2I8F4P3 |
| Locus tag | PTKU15_RS44770 | Protein ID | WP_052426841.1 |
| Coordinates | 222329..222865 (-) | Length | 179 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PTKU15_RS44740 (PTKU15_89420) | 217879..218244 | + | 366 | WP_229517512.1 | hypothetical protein | - |
| PTKU15_RS44745 (PTKU15_89430) | 218254..218436 | + | 183 | WP_229517513.1 | hypothetical protein | - |
| PTKU15_RS44750 (PTKU15_89460) | 220114..220350 | - | 237 | WP_229517514.1 | hypothetical protein | - |
| PTKU15_RS44755 (PTKU15_89470) | 220393..220839 | - | 447 | WP_229517515.1 | hypothetical protein | - |
| PTKU15_RS44760 (PTKU15_89480) | 220871..221389 | - | 519 | WP_229517516.1 | hypothetical protein | - |
| PTKU15_RS44765 (PTKU15_89490) | 221856..222332 | - | 477 | WP_229517517.1 | RES family NAD+ phosphorylase | Toxin |
| PTKU15_RS44770 (PTKU15_89500) | 222329..222865 | - | 537 | WP_052426841.1 | DUF2384 domain-containing protein | Antitoxin |
| PTKU15_RS44775 (PTKU15_89510) | 223531..225047 | + | 1517 | Protein_206 | sensor domain-containing diguanylate cyclase | - |
| PTKU15_RS44780 (PTKU15_89520) | 225063..225344 | - | 282 | WP_229517849.1 | hypothetical protein | - |
| PTKU15_RS44785 (PTKU15_89530) | 225668..225910 | + | 243 | WP_036001467.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| PTKU15_RS44790 (PTKU15_89540) | 225910..226230 | + | 321 | WP_229517518.1 | CcdB family protein | - |
| PTKU15_RS44795 (PTKU15_89550) | 226366..226713 | + | 348 | WP_229517519.1 | hypothetical protein | - |
| PTKU15_RS47560 (PTKU15_89560) | 227461..227595 | - | 135 | WP_284692632.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 159 a.a. Molecular weight: 17132.73 Da Isoelectric Point: 7.8490
>T40203 WP_229517517.1 NZ_AP025260:c222332-221856 [Paraburkholderia terrae]
VTVAVWRIATEAPNYPADDLSGAGAKVTGGRWNRRGTPVLYCASTIALACLETVVHIRAAGLPLNRYLVRLDVPDNVWQA
AMVFTNISAPIGWDAIPPGMTSLDTGEKWIYNAATALLLVPSVIVPEETNVLINPAHPDAAGIRAQKVRRWTYDQRMG
VTVAVWRIATEAPNYPADDLSGAGAKVTGGRWNRRGTPVLYCASTIALACLETVVHIRAAGLPLNRYLVRLDVPDNVWQA
AMVFTNISAPIGWDAIPPGMTSLDTGEKWIYNAATALLLVPSVIVPEETNVLINPAHPDAAGIRAQKVRRWTYDQRMG
Download Length: 477 bp
>T40203 NZ_AP025260:c222332-221856 [Paraburkholderia terrae]
GTGACGGTCGCGGTCTGGCGGATCGCGACCGAAGCGCCCAACTACCCCGCAGACGATCTTTCCGGTGCCGGCGCGAAGGT
GACGGGTGGCCGGTGGAACCGGCGCGGAACGCCGGTTTTGTACTGTGCGTCGACCATCGCCCTGGCCTGTCTGGAAACCG
TGGTTCACATTCGCGCGGCGGGATTGCCGCTGAACCGCTACCTCGTTCGTCTGGACGTGCCCGACAACGTCTGGCAGGCC
GCGATGGTTTTCACGAACATCTCGGCGCCCATCGGATGGGACGCAATCCCGCCCGGCATGACGAGCCTGGATACAGGTGA
GAAATGGATCTATAACGCCGCCACCGCCCTGCTTCTTGTGCCGTCCGTCATCGTCCCGGAGGAGACGAACGTCCTCATCA
ACCCGGCACATCCGGATGCCGCGGGCATTCGTGCACAGAAAGTACGGCGCTGGACCTACGATCAGCGAATGGGTTAA
GTGACGGTCGCGGTCTGGCGGATCGCGACCGAAGCGCCCAACTACCCCGCAGACGATCTTTCCGGTGCCGGCGCGAAGGT
GACGGGTGGCCGGTGGAACCGGCGCGGAACGCCGGTTTTGTACTGTGCGTCGACCATCGCCCTGGCCTGTCTGGAAACCG
TGGTTCACATTCGCGCGGCGGGATTGCCGCTGAACCGCTACCTCGTTCGTCTGGACGTGCCCGACAACGTCTGGCAGGCC
GCGATGGTTTTCACGAACATCTCGGCGCCCATCGGATGGGACGCAATCCCGCCCGGCATGACGAGCCTGGATACAGGTGA
GAAATGGATCTATAACGCCGCCACCGCCCTGCTTCTTGTGCCGTCCGTCATCGTCCCGGAGGAGACGAACGTCCTCATCA
ACCCGGCACATCCGGATGCCGCGGGCATTCGTGCACAGAAAGTACGGCGCTGGACCTACGATCAGCGAATGGGTTAA
Antitoxin
Download Length: 179 a.a. Molecular weight: 19187.98 Da Isoelectric Point: 10.3478
>AT40203 WP_052426841.1 NZ_AP025260:c222865-222329 [Paraburkholderia terrae]
VNAPATSARRPARKAAVRLPAKPAAPSRAAKVHATKINDYLTLYHAPPLERISFIKHGVDAHDVYVLARNMGTSQDNLMV
TLGLPRSTIIRKAKGKARLSAEQSERVIGMARLVGQVEAMVAESGDPAGFDAAHWVNEWLDQPNPALDQRRPAEFMDTVA
GQEFVAALLAKAQSGAYA
VNAPATSARRPARKAAVRLPAKPAAPSRAAKVHATKINDYLTLYHAPPLERISFIKHGVDAHDVYVLARNMGTSQDNLMV
TLGLPRSTIIRKAKGKARLSAEQSERVIGMARLVGQVEAMVAESGDPAGFDAAHWVNEWLDQPNPALDQRRPAEFMDTVA
GQEFVAALLAKAQSGAYA
Download Length: 537 bp
>AT40203 NZ_AP025260:c222865-222329 [Paraburkholderia terrae]
GTGAACGCGCCCGCCACCTCCGCCCGTCGCCCGGCCCGCAAGGCTGCAGTTCGTCTCCCGGCAAAACCCGCCGCGCCGTC
GCGGGCCGCCAAAGTGCATGCGACGAAGATCAACGACTACCTCACCCTCTATCACGCGCCTCCGCTCGAGCGCATCAGCT
TCATCAAGCACGGTGTGGATGCCCACGACGTGTACGTTCTTGCGCGCAACATGGGAACCTCGCAGGATAATCTGATGGTG
ACCTTGGGGTTGCCGCGCTCGACCATCATCCGTAAGGCCAAGGGGAAGGCGCGCCTGTCCGCGGAGCAGAGCGAACGGGT
GATCGGTATGGCAAGGCTGGTCGGCCAGGTCGAAGCGATGGTCGCGGAATCCGGTGATCCGGCAGGCTTCGACGCCGCCC
ACTGGGTGAACGAATGGCTGGACCAGCCCAACCCGGCACTGGATCAACGCCGTCCTGCCGAGTTCATGGATACGGTCGCG
GGACAGGAATTTGTCGCTGCCCTGCTGGCGAAGGCACAGAGCGGAGCGTATGCGTGA
GTGAACGCGCCCGCCACCTCCGCCCGTCGCCCGGCCCGCAAGGCTGCAGTTCGTCTCCCGGCAAAACCCGCCGCGCCGTC
GCGGGCCGCCAAAGTGCATGCGACGAAGATCAACGACTACCTCACCCTCTATCACGCGCCTCCGCTCGAGCGCATCAGCT
TCATCAAGCACGGTGTGGATGCCCACGACGTGTACGTTCTTGCGCGCAACATGGGAACCTCGCAGGATAATCTGATGGTG
ACCTTGGGGTTGCCGCGCTCGACCATCATCCGTAAGGCCAAGGGGAAGGCGCGCCTGTCCGCGGAGCAGAGCGAACGGGT
GATCGGTATGGCAAGGCTGGTCGGCCAGGTCGAAGCGATGGTCGCGGAATCCGGTGATCCGGCAGGCTTCGACGCCGCCC
ACTGGGTGAACGAATGGCTGGACCAGCCCAACCCGGCACTGGATCAACGCCGTCCTGCCGAGTTCATGGATACGGTCGCG
GGACAGGAATTTGTCGCTGCCCTGCTGGCGAAGGCACAGAGCGGAGCGTATGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|