Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 124388..124737 Replicon chromosome
Accession NZ_AP025260
Organism Paraburkholderia terrae strain KU-15

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PTKU15_RS44285 Protein ID WP_229517454.1
Coordinates 124627..124737 (+) Length 37 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A7Z7FNP7
Locus tag PTKU15_RS44280 Protein ID WP_009770832.1
Coordinates 124388..124630 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTKU15_RS44260 (PTKU15_88440) 119721..121115 + 1395 WP_091788751.1 replication initiation protein -
PTKU15_RS44265 (PTKU15_88450) 121406..121768 - 363 WP_229517448.1 hypothetical protein -
PTKU15_RS44270 (PTKU15_88470) 123138..123482 + 345 WP_229517450.1 hypothetical protein -
PTKU15_RS44275 (PTKU15_88480) 123800..124090 + 291 WP_229517452.1 hypothetical protein -
PTKU15_RS44280 (PTKU15_88490) 124388..124630 + 243 WP_009770832.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PTKU15_RS44285 124627..124737 + 111 WP_229517454.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PTKU15_RS44290 (PTKU15_88500) 124734..124928 + 195 WP_229517455.1 type II toxin-antitoxin system RelE/ParE family toxin -
PTKU15_RS44295 (PTKU15_88520) 125692..126084 + 393 WP_229517457.1 hypothetical protein -
PTKU15_RS44300 (PTKU15_88530) 126152..126484 - 333 WP_229517459.1 H-NS family nucleoid-associated regulatory protein -
PTKU15_RS44305 (PTKU15_88550) 127291..128139 - 849 WP_229517461.1 ABC transporter ATP-binding protein -
PTKU15_RS44310 (PTKU15_88560) 128142..129437 - 1296 WP_229517898.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 4209.68 Da        Isoelectric Point: 3.8570

>T40201 WP_229517454.1 NZ_AP025260:124627-124737 [Paraburkholderia terrae]
VKEFVLSPAAELDLDDIWDYSVENWGIRQAERYIPA

Download         Length: 111 bp

>T40201 NZ_AP025260:124627-124737 [Paraburkholderia terrae]
GTGAAGGAGTTTGTTCTTTCGCCGGCGGCCGAGCTGGATCTCGATGATATTTGGGACTATTCGGTAGAAAACTGGGGGAT
CCGGCAGGCAGAGCGCTATATCCCCGCATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8942.04 Da        Isoelectric Point: 8.6373

>AT40201 WP_009770832.1 NZ_AP025260:124388-124630 [Paraburkholderia terrae]
MGKNTSVSLGDHFAEFVEDRVRAGRYNTASDVVRAGLRLLEEQEAKLDALRVELEKGERSGPSRPFDFDAFLARKKKSAT

Download         Length: 243 bp

>AT40201 NZ_AP025260:124388-124630 [Paraburkholderia terrae]
ATGGGCAAAAACACCTCCGTTTCGCTCGGCGACCACTTCGCCGAGTTTGTCGAAGATCGCGTGCGTGCCGGTCGCTACAA
CACGGCGAGCGATGTGGTTCGGGCTGGCCTGCGTTTGCTGGAGGAACAGGAAGCAAAACTCGATGCTCTACGCGTCGAGC
TGGAGAAAGGCGAGCGCTCGGGTCCGTCGAGGCCGTTTGACTTCGACGCGTTTCTCGCACGCAAGAAGAAGTCCGCGACG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7FNP7

References