Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 113729..114390 Replicon chromosome
Accession NZ_AP025260
Organism Paraburkholderia terrae strain KU-15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PTKU15_RS44240 Protein ID WP_091788766.1
Coordinates 113729..114160 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PTKU15_RS44245 Protein ID WP_229517446.1
Coordinates 114160..114390 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTKU15_RS44225 (PTKU15_88350) 109809..110801 - 993 WP_229517441.1 substrate-binding domain-containing protein -
PTKU15_RS44230 (PTKU15_88360) 110916..112085 + 1170 WP_229517442.1 LacI family DNA-binding transcriptional regulator -
PTKU15_RS44235 (PTKU15_88370) 112374..112880 - 507 WP_229517444.1 hypothetical protein -
PTKU15_RS44240 (PTKU15_88380) 113729..114160 - 432 WP_091788766.1 PIN domain-containing protein Toxin
PTKU15_RS44245 (PTKU15_88390) 114160..114390 - 231 WP_229517446.1 CopG family transcriptional regulator Antitoxin
PTKU15_RS47550 (PTKU15_88400) 114626..114760 - 135 WP_279634511.1 hypothetical protein -
PTKU15_RS44250 (PTKU15_88420) 116487..117476 - 990 WP_091788757.1 ParB/RepB/Spo0J family partition protein -
PTKU15_RS44255 (PTKU15_88430) 117473..118678 - 1206 WP_091788754.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15605.73 Da        Isoelectric Point: 5.7708

>T40200 WP_091788766.1 NZ_AP025260:c114160-113729 [Paraburkholderia terrae]
MTYLLDVNVLIALLDAGHVQHEAAHEWFGRAGHAAWATCPLTENGVLRIIGNPRYPNTLETPAAVAPLVAQLRAHPGHAF
WSDDLSMLDPEYVDLNRVLATDQVTDTYLLALARRHGGALATFDRRLVADAVPDGARHLELIG

Download         Length: 432 bp

>T40200 NZ_AP025260:c114160-113729 [Paraburkholderia terrae]
ATGACTTATCTGCTTGACGTCAACGTACTGATTGCGCTGCTCGACGCGGGCCACGTACAGCACGAGGCCGCGCACGAATG
GTTCGGCCGGGCAGGGCACGCCGCTTGGGCGACCTGCCCGCTGACCGAAAACGGCGTGCTGCGCATCATCGGCAATCCGC
GCTACCCGAACACACTGGAGACGCCGGCCGCGGTCGCGCCGCTCGTCGCGCAACTTCGAGCACATCCTGGCCACGCCTTC
TGGTCTGACGACCTGAGCATGCTCGATCCGGAGTATGTTGACTTGAACCGCGTCCTCGCGACCGACCAGGTGACCGACAC
GTACCTGCTCGCCCTCGCGCGCCGCCATGGAGGGGCGCTGGCCACCTTCGACCGCCGGCTGGTCGCCGATGCGGTGCCCG
ACGGTGCGCGCCACCTCGAACTCATTGGTTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8280.48 Da        Isoelectric Point: 11.5000

>AT40200 WP_229517446.1 NZ_AP025260:c114390-114160 [Paraburkholderia terrae]
MRTTLDIDDDVLALARARADREHVSIGRIISQLARAALQRPAVAPATRNGLPVLPNARTARTVTPEVVNQMRDEAP

Download         Length: 231 bp

>AT40200 NZ_AP025260:c114390-114160 [Paraburkholderia terrae]
ATGCGAACCACCCTAGATATCGACGACGACGTGCTCGCCCTCGCACGCGCGCGCGCCGACCGCGAGCACGTGTCGATCGG
TCGCATCATCTCGCAACTCGCGCGCGCGGCGCTGCAGCGTCCCGCAGTCGCTCCGGCCACGCGCAACGGCTTGCCGGTGC
TGCCGAACGCGCGCACCGCGCGCACGGTCACGCCTGAAGTCGTCAACCAGATGCGCGACGAGGCGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References