Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-AbrB
Location 1541032..1541623 Replicon chromosome
Accession NZ_AP025226
Organism Saccharolobus caldissimus strain JCM 32116

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SACC_RS08550 Protein ID WP_229569050.1
Coordinates 1541255..1541623 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SACC_RS08545 Protein ID WP_229569049.1
Coordinates 1541032..1541274 (+) Length 81 a.a.

Genomic Context

SACC_RS08520SACC_RS08525SACC_RS08530SACC_RS08535SACC_RS08540SACC_RS08545SACC_RS08550SACC_RS08555SACC_RS08560SACC_RS08565SACC_RS08580SACC_RS08570SACC_RS08575
Location: 1536532..1538205 (1674 bp)
Type: Others
Protein ID: WP_229572499.1
Location: 1538293..1538694 (402 bp)
Type: Others
Protein ID: WP_229569045.1
Location: 1538681..1539277 (597 bp)
Type: Others
Protein ID: WP_229569046.1
Location: 1539274..1539903 (630 bp)
Type: Others
Protein ID: WP_229569047.1
Location: 1539881..1540489 (609 bp)
Type: Others
Protein ID: WP_229569048.1
Location: 1541032..1541274 (243 bp)
Type: Antitoxin
Protein ID: WP_229569049.1
Location: 1541255..1541623 (369 bp)
Type: Toxin
Protein ID: WP_229569050.1
Location: 1542049..1542408 (360 bp)
Type: Others
Protein ID: WP_229569051.1
Location: 1542405..1542959 (555 bp)
Type: Others
Protein ID: WP_229572588.1
Location: 1543102..1543317 (216 bp)
Type: Others
Protein ID: WP_229569052.1
Location: 1544348..1545718 (1371 bp)
Type: Others
Protein ID: WP_229569055.1
Location: 1543353..1543652 (300 bp)
Type: Others
Protein ID: WP_229569053.1
Location: 1543642..1544100 (459 bp)
Type: Others
Protein ID: WP_229569054.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SACC_RS08520 (SACC_16770)1536532..1538205+1674WP_229572499.1urease subunit alpha-
SACC_RS08525 (SACC_16780)1538293..1538694+402WP_229569045.1hypothetical protein-
SACC_RS08530 (SACC_16790)1538681..1539277+597WP_229569046.1urease accessory UreF family protein-
SACC_RS08535 (SACC_16800)1539274..1539903+630WP_229569047.1urease accessory protein UreG-
SACC_RS08540 (SACC_16810)1539881..1540489+609WP_229569048.1urease accessory protein UreD-
SACC_RS08545 (SACC_16820)1541032..1541274+243WP_229569049.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
SACC_RS08550 (SACC_16830)1541255..1541623+369WP_229569050.1PIN domain-containing proteinToxin
SACC_RS08555 (SACC_16840)1542049..1542408+360WP_229569051.1hypothetical protein-
SACC_RS08560 (SACC_16850)1542405..1542959+555WP_229572588.1hypothetical protein-
SACC_RS08565 (SACC_16860)1543102..1543317+216WP_229569052.1hypothetical protein-
SACC_RS08570 (SACC_16870)1543353..1543652-300WP_229569053.1hypothetical protein-
SACC_RS08575 (SACC_16880)1543642..1544100-459WP_229569054.1hypothetical protein-
SACC_RS08580 (SACC_16890)1544348..1545718+1371WP_229569055.1cytochrome ubiquinol oxidase subunit I-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-120)

Antitoxin

SpoVT-AbrB domain

(4-46)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 14299.55 Da        Isoelectric Point: 4.9617

>T40170 WP_229569050.1 NZ_AP025226:1541255-1541623 [Saccharolobus caldissimus]
MEEVVVDTNFVIAVIFEDHIFHKLAIEDWGKIHKAYLPIIAVSELAYFLIKNRFNLDDVLENVLSDPKIEVVENTLEDVY
FAIRNSPKSYDDFNDYMIISLAKRLGLKILTYDDKMKRKQKS

Download         Length: 369 bp

>T40170 NZ_AP025226:1541255-1541623 [Saccharolobus caldissimus]
TTGGAAGAAGTAGTAGTTGATACCAATTTTGTGATTGCTGTAATTTTTGAGGATCATATTTTTCATAAATTAGCAATAGA
GGATTGGGGAAAAATACACAAAGCTTATTTGCCTATAATCGCCGTTTCTGAACTTGCATACTTCTTAATAAAAAATAGAT
TTAATTTAGATGATGTTTTAGAAAATGTTTTATCTGATCCGAAGATAGAAGTAGTCGAAAATACTTTAGAGGATGTATAT
TTTGCAATAAGAAATTCGCCTAAATCCTATGATGATTTTAACGATTATATGATAATTTCTCTAGCTAAAAGATTGGGACT
TAAAATACTTACTTATGACGATAAAATGAAAAGAAAACAAAAAAGTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9014.38 Da        Isoelectric Point: 10.0013

>AT40170 WP_229569049.1 NZ_AP025226:1541032-1541274 [Saccharolobus caldissimus]
VEEVKVTRNYQITIPSTIRAKLNIRVGDKLLVYVENNKIIIEKKSGNITSLNLRLGRKFTDEDINKIIAEAGEEIGRSSS

Download         Length: 243 bp

>AT40170 NZ_AP025226:1541032-1541274 [Saccharolobus caldissimus]
GTGGAAGAAGTTAAAGTTACGAGAAACTATCAGATAACTATCCCCTCCACGATTAGAGCTAAACTAAATATTCGAGTTGG
TGACAAACTATTAGTTTATGTTGAAAATAATAAAATAATCATAGAAAAGAAAAGCGGAAATATCACATCGTTAAACCTTA
GGTTAGGTAGAAAGTTTACCGATGAAGATATTAACAAAATCATAGCCGAGGCCGGAGAGGAAATTGGAAGAAGTAGTAGT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References