Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1987359..1987630 Replicon chromosome
Accession NZ_AP025220
Organism Escherichia coli strain 2017.11.01CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1987489..1987592 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1987359..1987630 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH31_RS09605 1983914..1984576 - 663 WP_000944258.1 exodeoxyribonuclease X -
LPH31_RS09610 1984600..1985256 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LPH31_RS09615 1985358..1985588 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LPH31_RS09620 1985727..1986101 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LPH31_RS09625 1986105..1986977 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
LPH31_RS09630 1986990..1987331 + 342 WP_000976472.1 YebY family protein -
- 1987359..1987630 - 272 - - Antitoxin
- 1987489..1987592 + 104 - - Toxin
LPH31_RS09635 1987727..1988383 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
LPH31_RS09640 1988384..1988575 - 192 WP_001338167.1 YebW family protein -
LPH31_RS09645 1988680..1988916 - 237 WP_001338166.1 YebV family protein -
LPH31_RS09650 1989034..1990473 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T40149 NZ_AP025220:1987489-1987592 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT40149 NZ_AP025220:c1987630-1987359 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References