Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 292589..292857 Replicon chromosome
Accession NZ_AP025214
Organism Escherichia coli strain 2017.09.02CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 292717..292819 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 292589..292857 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH32_RS01515 289142..289804 - 663 WP_000944256.1 exodeoxyribonuclease X -
LPH32_RS01520 289828..290484 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LPH32_RS01525 290586..290816 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LPH32_RS01530 290955..291329 + 375 WP_000168737.1 CopC domain-containing protein YobA -
LPH32_RS01535 291333..292205 + 873 WP_000879323.1 copper homeostasis membrane protein CopD -
LPH32_RS01540 292218..292559 + 342 WP_000976472.1 YebY family protein -
- 292589..292857 - 269 - - Antitoxin
- 292717..292819 + 103 - - Toxin
LPH32_RS01545 292954..293610 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
LPH32_RS01550 293611..293802 - 192 WP_001317886.1 YebW family protein -
LPH32_RS01555 293907..294143 - 237 WP_001295499.1 YebV family protein -
LPH32_RS01560 294261..295700 - 1440 WP_001317885.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 269537..298413 28876


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T40116 NZ_AP025214:292717-292819 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT40116 NZ_AP025214:c292857-292589 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References