Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1947332..1947603 Replicon chromosome
Accession NZ_AP025209
Organism Escherichia coli strain 2017.06.04CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1947462..1947565 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1947332..1947603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH28_RS09270 1943888..1944550 - 663 WP_000944256.1 exodeoxyribonuclease X -
LPH28_RS09275 1944574..1945230 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LPH28_RS09280 1945332..1945562 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LPH28_RS09285 1945701..1946075 + 375 WP_000255065.1 CopC domain-containing protein YobA -
LPH28_RS09290 1946079..1946951 + 873 WP_000879297.1 copper homeostasis membrane protein CopD -
LPH28_RS09295 1946964..1947305 + 342 WP_000976472.1 YebY family protein -
- 1947332..1947603 - 272 - - Antitoxin
- 1947462..1947565 + 104 - - Toxin
LPH28_RS09300 1947700..1948356 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LPH28_RS09305 1948357..1948548 - 192 WP_001296140.1 YebW family protein -
LPH28_RS09310 1948653..1948889 - 237 WP_001295499.1 YebV family protein -
LPH28_RS09315 1949007..1950446 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T40098 NZ_AP025209:1947462-1947565 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT40098 NZ_AP025209:c1947603-1947332 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References