Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 200883..201388 Replicon chromosome
Accession NZ_AP025185
Organism Flavobacterium ammonificans strain SHINM13

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag LPC20_RS00900 Protein ID WP_229325583.1
Coordinates 201134..201388 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LPC20_RS00895 Protein ID WP_229325581.1
Coordinates 200883..201137 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPC20_RS00880 (SHINM13_01670) 196384..197481 + 1098 WP_229325575.1 acyl-CoA desaturase -
LPC20_RS00885 (SHINM13_01680) 197543..198730 + 1188 WP_229325577.1 pyridoxal phosphate-dependent aminotransferase -
LPC20_RS00890 (SHINM13_01690) 198957..200819 + 1863 WP_229325579.1 U32 family peptidase -
LPC20_RS00895 (SHINM13_01700) 200883..201137 + 255 WP_229325581.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LPC20_RS00900 (SHINM13_01710) 201134..201388 + 255 WP_229325583.1 Txe/YoeB family addiction module toxin Toxin
LPC20_RS00905 (SHINM13_01720) 201407..201730 + 324 WP_229325586.1 DUF6370 family protein -
LPC20_RS00910 (SHINM13_01730) 201743..202459 + 717 WP_229325588.1 pirin family protein -
LPC20_RS00915 (SHINM13_01740) 202556..203428 + 873 WP_229325590.1 ACP S-malonyltransferase -
LPC20_RS00920 (SHINM13_01750) 203510..204184 + 675 WP_229325592.1 peptidoglycan DD-metalloendopeptidase family protein -
LPC20_RS00925 (SHINM13_01770) 204502..204696 - 195 WP_229325594.1 hypothetical protein -
LPC20_RS00930 (SHINM13_01780) 204783..205796 - 1014 WP_229325596.1 UDP-glucose 4-epimerase GalE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10235.74 Da        Isoelectric Point: 9.0292

>T40059 WP_229325583.1 NZ_AP025185:201134-201388 [Flavobacterium ammonificans]
MIVSWQLQAWEDYLYWQKTDKSKLKRINELIKSCIRTPFEGIGNPEGLKHDLQGFWSRRIDSEHRLVYTFRESNIIIVSC
RYHY

Download         Length: 255 bp

>T40059 NZ_AP025185:201134-201388 [Flavobacterium ammonificans]
ATGATAGTTTCTTGGCAACTTCAGGCATGGGAAGATTATTTGTATTGGCAAAAAACCGATAAATCCAAACTCAAACGAAT
CAACGAATTAATCAAATCGTGTATTCGAACTCCTTTTGAAGGCATTGGAAATCCGGAAGGATTGAAACATGATTTGCAAG
GATTTTGGTCAAGAAGAATCGACTCAGAACACCGATTGGTTTACACCTTTAGAGAATCCAACATAATCATTGTTTCTTGT
AGGTATCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9942.43 Da        Isoelectric Point: 4.5386

>AT40059 WP_229325581.1 NZ_AP025185:200883-201137 [Flavobacterium ammonificans]
MKVINYTDLRLNLKKWMDSVTDDMEEIIVKRKDNKDLVLISLEEYNALNETNYLLSGKNRDILLQSVKDIQENKSLVQKE
LIEE

Download         Length: 255 bp

>AT40059 NZ_AP025185:200883-201137 [Flavobacterium ammonificans]
ATGAAAGTCATCAATTACACTGATTTACGATTGAATCTAAAAAAATGGATGGATTCCGTTACAGATGATATGGAAGAAAT
AATTGTAAAGCGAAAAGACAACAAAGACCTTGTTTTGATTTCGTTGGAAGAATACAATGCTTTAAATGAAACCAACTATT
TATTATCTGGAAAAAACAGAGACATCTTACTTCAATCTGTAAAAGACATTCAAGAAAACAAATCATTAGTTCAAAAAGAG
TTAATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References