Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 172034..172539 Replicon chromosome
Accession NZ_AP025183
Organism Flavobacterium ammonificans strain GENT11

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag LPC23_RS00795 Protein ID WP_229330313.1
Coordinates 172285..172539 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LPC23_RS00790 Protein ID WP_229331599.1
Coordinates 172034..172288 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPC23_RS00775 (GENT11_01470) 167166..168263 + 1098 WP_229330307.1 acyl-CoA desaturase -
LPC23_RS00780 (GENT11_01480) 168325..169512 + 1188 WP_229330309.1 pyridoxal phosphate-dependent aminotransferase -
LPC23_RS00785 (GENT11_01490) 169740..171602 + 1863 WP_229330311.1 U32 family peptidase -
LPC23_RS00790 (GENT11_01500) 172034..172288 + 255 WP_229331599.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LPC23_RS00795 172285..172539 + 255 WP_229330313.1 Txe/YoeB family addiction module toxin Toxin
LPC23_RS00800 (GENT11_01510) 172558..172881 + 324 WP_229330315.1 DUF6370 family protein -
LPC23_RS00805 (GENT11_01520) 172893..173609 + 717 WP_229330317.1 pirin family protein -
LPC23_RS00810 (GENT11_01530) 173706..174578 + 873 WP_229330319.1 ACP S-malonyltransferase -
LPC23_RS00815 (GENT11_01540) 174661..175335 + 675 WP_229330321.1 peptidoglycan DD-metalloendopeptidase family protein -
LPC23_RS00820 (GENT11_01550) 175346..175669 - 324 WP_229330323.1 hypothetical protein -
LPC23_RS00825 (GENT11_01560) 175654..175848 - 195 WP_229330325.1 hypothetical protein -
LPC23_RS00830 (GENT11_01570) 175935..176948 - 1014 WP_229330327.1 UDP-glucose 4-epimerase GalE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-66)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10159.64 Da        Isoelectric Point: 9.0725

>T40058 WP_229330313.1 NZ_AP025183:172285-172539 [Flavobacterium ammonificans]
MIVSWQLQAWEDYLYWQKTDKSKLKRINELIKSCIRTPFEGIGNPEGLKHDLQGFWSRRIDSEHRLVSTFRESNIIIVSC
RYHY

Download         Length: 255 bp

>T40058 NZ_AP025183:172285-172539 [Flavobacterium ammonificans]
ATGATAGTTTCTTGGCAACTTCAGGCATGGGAAGATTATTTGTATTGGCAAAAAACCGATAAATCCAAACTCAAACGAAT
CAACGAATTAATTAAATCGTGTATTCGAACTCCTTTTGAAGGCATTGGAAACCCGGAAGGATTGAAACATGATTTGCAAG
GATTTTGGTCAAGAAGAATCGACTCAGAACACCGATTGGTTTCCACCTTTAGAGAATCCAACATAATCATTGTTTCTTGT
AGGTATCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9908.40 Da        Isoelectric Point: 4.5386

>AT40058 WP_229331599.1 NZ_AP025183:172034-172288 [Flavobacterium ammonificans]
IKVINYTDLRLNLKKWMDAVTDDMEEIIVKRKDNKDLVLISLEEYNALNETNYLLSGKNRDILLQSVKDIQENKSLVQKE
LIEE

Download         Length: 255 bp

>AT40058 NZ_AP025183:172034-172288 [Flavobacterium ammonificans]
ATAAAAGTCATCAATTACACTGATTTACGATTGAATCTAAAAAAATGGATGGATGCCGTTACAGATGATATGGAAGAAAT
AATTGTAAAGCGAAAAGACAACAAAGACCTTGTTTTGATTTCGCTAGAAGAATACAATGCTTTAAATGAAACCAACTATT
TATTATCTGGAAAAAACAGAGATATCTTACTTCAATCTGTAAAAGACATTCAAGAAAACAAATCATTAGTTCAAAAAGAG
TTAATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References