Detailed information of TA system TA039983

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 2833482..2834025
• Replicon: chromosome
• Accession: NZ_AP025171
• Organism: Cupriavidus sp. P-10

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CTP10_RS29655
• Protein ID: WP_116319093.1
• Coordinates: 2833482..2833772 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: CTP10_RS29660
• Protein ID: WP_116319094.1
• Coordinates: 2833759..2834025 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTP10_RS29640 (CTP10_R59420)	2829212..2830864	-	1653	WP_116319091.1	phospholipase D family protein	-
CTP10_RS29645 (CTP10_R59430)	2831349..2832875	+	1527	WP_116319326.1	amino acid permease	-
CTP10_RS29650 (CTP10_R59440)	2833117..2833461	+	345	WP_116319092.1	lysozyme inhibitor LprI family protein	-
CTP10_RS29655 (CTP10_R59450)	2833482..2833772	-	291	WP_116319093.1	type II toxin-antitoxin system YafQ family toxin	Toxin
CTP10_RS29660 (CTP10_R59460)	2833759..2834025	-	267	WP_116319094.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CTP10_RS29665 (CTP10_R59470)	2834355..2836517	+	2163	WP_116319095.1	TonB-dependent receptor	-
CTP10_RS29670 (CTP10_R59480)	2836868..2838403	+	1536	WP_116319096.1	NCS1 family nucleobase:cation symporter-1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-83)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10948.64 Da
• Isoelectric Point: 7.7029

>T39983 WP_116319093.1 NZ_AP025171:c2833772-2833482 [Cupriavidus sp. P-10]
MRMIEPTSQFRRDYKRELKGPYRLALQGQENELSAIIELLACDEALPARCRDHGLGGALRDCRDCHVRPDLLLIYRKPDA
GTLQLIRLGSHSELGF

Nucleotide

• Length: 291 bp

>T39983 NZ_AP025171:c2833772-2833482 [Cupriavidus sp. P-10]
ATGAGGATGATTGAACCGACGAGCCAGTTCAGACGAGACTACAAACGCGAACTGAAAGGTCCATACCGATTGGCGCTGCA
GGGCCAGGAAAATGAACTTTCCGCCATTATCGAATTGCTGGCGTGCGACGAGGCCTTGCCTGCGCGATGCCGCGACCACG
GCCTGGGCGGCGCGTTGCGGGACTGCCGGGACTGCCATGTCAGGCCGGACCTCCTGCTGATCTATCGGAAGCCCGATGCT
GGAACGCTTCAGTTGATCCGGCTGGGCTCGCACAGCGAACTGGGCTTCTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9312.76 Da
• Isoelectric Point: 4.4883

>AT39983 WP_116319094.1 NZ_AP025171:c2834025-2833759 [Cupriavidus sp. P-10]
MPASTFVRTRIDQQIKDEAAAVLEAMGLTVSDAVRMLLTRIALEQALPSGLMTPNPATIAALKEARAGGLRKFGSVAALM
ADLNDEDD

Nucleotide

• Length: 267 bp

>AT39983 NZ_AP025171:c2834025-2833759 [Cupriavidus sp. P-10]
ATGCCCGCCTCGACCTTCGTTCGCACCCGGATCGACCAGCAAATCAAGGACGAGGCCGCGGCCGTGCTGGAAGCGATGGG
CCTGACCGTTTCCGACGCCGTTCGCATGTTGTTGACCCGTATCGCGCTGGAGCAGGCTTTGCCTTCGGGGCTGATGACTC
CGAACCCTGCAACCATTGCAGCGCTGAAAGAAGCGCGGGCCGGCGGCCTGCGCAAATTCGGGTCCGTGGCGGCGTTGATG
GCGGATCTCAACGATGAGGATGATTGA