39972

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1436486..1436933 Replicon chromosome
Accession NZ_AP025169
Organism Pseudomonas sp. CYM-20-01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M2497_RS06330 Protein ID WP_248486385.1
Coordinates 1436664..1436933 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M2497_RS06325 Protein ID WP_248486382.1
Coordinates 1436486..1436674 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2497_RS06300 (cym2001_12340) 1431816..1433186 + 1371 WP_248486375.1 aromatic acid/H+ symport family MFS transporter -
M2497_RS06305 (cym2001_12350) 1433338..1434141 - 804 WP_248486377.1 transglutaminase family protein -
M2497_RS06310 (cym2001_12360) 1434329..1435348 + 1020 WP_248486379.1 Glu/Leu/Phe/Val dehydrogenase dimerization domain-containing protein -
M2497_RS06315 (cym2001_12370) 1435403..1435663 - 261 WP_003171979.1 YebG family protein -
M2497_RS06320 (cym2001_12380) 1436087..1436332 + 246 WP_248486380.1 DUF6124 family protein -
M2497_RS06325 (cym2001_12390) 1436486..1436674 + 189 WP_248486382.1 antitoxin Antitoxin
M2497_RS06330 1436664..1436933 + 270 WP_248486385.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M2497_RS06335 (cym2001_12400) 1437102..1437590 + 489 WP_058427808.1 phosphate-starvation-inducible PsiE family protein -
M2497_RS06340 (cym2001_12410) 1437587..1437901 - 315 WP_058427809.1 DUF3509 domain-containing protein -
M2497_RS06345 (cym2001_12420) 1438189..1439475 - 1287 WP_248486387.1 serine/threonine transporter -
M2497_RS06350 (cym2001_12430) 1439537..1440913 - 1377 WP_248486389.1 L-serine ammonia-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10436.32 Da        Isoelectric Point: 10.9886

>T39972 WP_248486385.1 NZ_AP025169:1436664-1436933 [Pseudomonas sp. CYM-20-01]
MLIEWVPAARVELRQIIEYLNHRNPVAALELKRSIEASVLALSRRPHLYRPGRILGTREMVVHPNYLVVYKVTDNIRVLS
VLHARQRYP

Download         Length: 270 bp

>T39972 NZ_AP025169:1436664-1436933 [Pseudomonas sp. CYM-20-01]
ATGCTGATTGAGTGGGTGCCCGCAGCGCGGGTCGAACTTCGGCAAATTATTGAATACCTCAATCATCGCAATCCTGTAGC
AGCTCTTGAGCTAAAGCGCTCAATCGAAGCTTCAGTTCTGGCTCTCTCCCGCAGACCCCATCTTTACCGTCCTGGCAGAA
TCCTCGGTACGCGCGAGATGGTGGTACATCCGAATTACCTGGTCGTTTACAAGGTGACAGACAACATTCGGGTTCTCTCT
GTTTTACACGCACGCCAGCGATATCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6864.47 Da        Isoelectric Point: 4.0197

>AT39972 WP_248486382.1 NZ_AP025169:1436486-1436674 [Pseudomonas sp. CYM-20-01]
MDTSFSSGTQADTEEQADSYDRWFRAKIQAALEDTSPGIPHDEVMAEMQALIESKLKKGDAD

Download         Length: 189 bp

>AT39972 NZ_AP025169:1436486-1436674 [Pseudomonas sp. CYM-20-01]
ATGGACACTTCCTTTTCCTCTGGTACCCAGGCAGATACCGAAGAGCAGGCCGATAGCTACGACCGCTGGTTTCGCGCCAA
GATACAAGCTGCTCTTGAAGACACCAGCCCCGGCATTCCTCACGATGAGGTGATGGCCGAGATGCAAGCGCTGATCGAGT
CCAAACTCAAGAAAGGCGATGCTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References