Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 1876443..1877080 | Replicon | chromosome |
| Accession | NZ_AP025160 | ||
| Organism | Acidithiobacillus ferrooxidans strain NFP31 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | ANFP_RS09610 | Protein ID | WP_012536995.1 |
| Coordinates | 1876443..1876853 (-) | Length | 137 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | B7J4Y7 |
| Locus tag | ANFP_RS09615 | Protein ID | WP_009567455.1 |
| Coordinates | 1876850..1877080 (-) | Length | 77 a.a. |
Genomic Context
Location: 1877232..1877354 (123 bp)
Type: Others
Protein ID: WP_257246597.1
Type: Others
Protein ID: WP_257246597.1
Location: 1879206..1880918 (1713 bp)
Type: Others
Protein ID: WP_009566247.1
Type: Others
Protein ID: WP_009566247.1
Location: 1880905..1881387 (483 bp)
Type: Others
Protein ID: WP_009566245.1
Type: Others
Protein ID: WP_009566245.1
Location: 1873023..1874090 (1068 bp)
Type: Others
Protein ID: WP_225487051.1
Type: Others
Protein ID: WP_225487051.1
Location: 1874225..1875259 (1035 bp)
Type: Others
Protein ID: WP_012536992.1
Type: Others
Protein ID: WP_012536992.1
Location: 1875263..1875712 (450 bp)
Type: Others
Protein ID: WP_012536993.1
Type: Others
Protein ID: WP_012536993.1
Location: 1876443..1876853 (411 bp)
Type: Toxin
Protein ID: WP_012536995.1
Type: Toxin
Protein ID: WP_012536995.1
Location: 1876850..1877080 (231 bp)
Type: Antitoxin
Protein ID: WP_009567455.1
Type: Antitoxin
Protein ID: WP_009567455.1
Location: 1877383..1878903 (1521 bp)
Type: Others
Protein ID: WP_012536996.1
Type: Others
Protein ID: WP_012536996.1
Location: 1881400..1882023 (624 bp)
Type: Others
Protein ID: WP_225487052.1
Type: Others
Protein ID: WP_225487052.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ANFP_RS09590 (ANFP_19240) | 1873023..1874090 | - | 1068 | WP_225487051.1 | phytoene/squalene synthase family protein | - |
| ANFP_RS09595 (ANFP_19250) | 1874225..1875259 | - | 1035 | WP_012536992.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| ANFP_RS09600 (ANFP_19260) | 1875263..1875712 | - | 450 | WP_012536993.1 | protein-export chaperone SecB | - |
| ANFP_RS09610 (ANFP_19270) | 1876443..1876853 | - | 411 | WP_012536995.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
| ANFP_RS09615 (ANFP_19280) | 1876850..1877080 | - | 231 | WP_009567455.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| ANFP_RS16620 | 1877232..1877354 | + | 123 | WP_257246597.1 | hypothetical protein | - |
| ANFP_RS09620 (ANFP_19290) | 1877383..1878903 | - | 1521 | WP_012536996.1 | aldehyde dehydrogenase family protein | - |
| ANFP_RS09625 (ANFP_19300) | 1879206..1880918 | + | 1713 | WP_009566247.1 | proline--tRNA ligase | - |
| ANFP_RS09630 (ANFP_19310) | 1880905..1881387 | + | 483 | WP_009566245.1 | universal stress protein | - |
| ANFP_RS09635 (ANFP_19320) | 1881400..1882023 | - | 624 | WP_225487052.1 | ABC-type transport auxiliary lipoprotein family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 15375.79 Da Isoelectric Point: 8.0756
>T39964 WP_012536995.1 NZ_AP025160:c1876853-1876443 [Acidithiobacillus ferrooxidans]
VIKYLLDTNICIFTIKNKPPEIREQFRQHHGQMAISTVTLMELIYGAEKSQVPERNLAEVEGFAARLEVLEFGSEAAKHT
GQLRAELAKIGKPIGPYDQMIAGHARSLGLFVVTNNLREFERVPGLRVMDWQSSRL
VIKYLLDTNICIFTIKNKPPEIREQFRQHHGQMAISTVTLMELIYGAEKSQVPERNLAEVEGFAARLEVLEFGSEAAKHT
GQLRAELAKIGKPIGPYDQMIAGHARSLGLFVVTNNLREFERVPGLRVMDWQSSRL
Download Length: 411 bp
>T39964 NZ_AP025160:c1876853-1876443 [Acidithiobacillus ferrooxidans]
GTGATCAAATACCTGCTGGATACCAATATCTGCATCTTTACTATCAAGAACAAGCCACCGGAGATCCGCGAACAGTTCCG
TCAGCACCATGGGCAAATGGCTATCAGCACCGTCACCTTGATGGAGTTGATCTATGGCGCGGAGAAATCACAGGTACCGG
AACGCAACCTGGCCGAAGTTGAAGGGTTCGCCGCCAGGCTGGAAGTGCTCGAATTCGGGAGCGAAGCCGCCAAGCATACT
GGGCAGCTCCGCGCAGAACTGGCCAAGATCGGCAAACCCATCGGGCCTTATGACCAGATGATCGCAGGCCACGCCAGAAG
CCTGGGATTGTTTGTCGTGACCAACAACTTGCGGGAATTCGAGCGCGTTCCGGGATTGCGGGTCATGGATTGGCAGAGCT
CACGCCTGTGA
GTGATCAAATACCTGCTGGATACCAATATCTGCATCTTTACTATCAAGAACAAGCCACCGGAGATCCGCGAACAGTTCCG
TCAGCACCATGGGCAAATGGCTATCAGCACCGTCACCTTGATGGAGTTGATCTATGGCGCGGAGAAATCACAGGTACCGG
AACGCAACCTGGCCGAAGTTGAAGGGTTCGCCGCCAGGCTGGAAGTGCTCGAATTCGGGAGCGAAGCCGCCAAGCATACT
GGGCAGCTCCGCGCAGAACTGGCCAAGATCGGCAAACCCATCGGGCCTTATGACCAGATGATCGCAGGCCACGCCAGAAG
CCTGGGATTGTTTGTCGTGACCAACAACTTGCGGGAATTCGAGCGCGTTCCGGGATTGCGGGTCATGGATTGGCAGAGCT
CACGCCTGTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8573.77 Da Isoelectric Point: 5.0508
>AT39964 WP_009567455.1 NZ_AP025160:c1877080-1876850 [Acidithiobacillus ferrooxidans]
MEHATVFQINRSQAIRLPKSIAFPADVKRVEVVAIGRMRILVPAGESWESWFDGEGVSADFMESREQPAGQFREPL
MEHATVFQINRSQAIRLPKSIAFPADVKRVEVVAIGRMRILVPAGESWESWFDGEGVSADFMESREQPAGQFREPL
Download Length: 231 bp
>AT39964 NZ_AP025160:c1877080-1876850 [Acidithiobacillus ferrooxidans]
ATGGAGCATGCCACTGTTTTTCAGATCAACCGTAGCCAGGCGATACGTCTGCCCAAGTCGATAGCCTTTCCGGCAGATGT
GAAGCGCGTAGAGGTGGTCGCCATAGGCCGCATGCGCATTCTGGTTCCTGCCGGAGAGTCCTGGGAGAGCTGGTTCGATG
GAGAAGGGGTCAGCGCCGACTTCATGGAAAGCCGTGAGCAACCCGCCGGCCAGTTCCGGGAACCGTTGTGA
ATGGAGCATGCCACTGTTTTTCAGATCAACCGTAGCCAGGCGATACGTCTGCCCAAGTCGATAGCCTTTCCGGCAGATGT
GAAGCGCGTAGAGGTGGTCGCCATAGGCCGCATGCGCATTCTGGTTCCTGCCGGAGAGTCCTGGGAGAGCTGGTTCGATG
GAGAAGGGGTCAGCGCCGACTTCATGGAAAGCCGTGAGCAACCCGCCGGCCAGTTCCGGGAACCGTTGTGA
Structures
Toxin
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Source | ID | Structure |
|---|---|---|
| No matching records found | ||
Antitoxin
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Source | ID | Structure |
|---|---|---|
| AlphaFold DB | B7J4Y7 |