Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1746693..1747492 Replicon chromosome
Accession NZ_AP025153
Organism Vibrio penaeicida strain TUMSAT-OK1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LDP65_RS26840 Protein ID WP_126610250.1
Coordinates 1746693..1747226 (-) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LDP65_RS26845 Protein ID WP_126610249.1
Coordinates 1747223..1747492 (-) Length 90 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDP65_RS26805 1742001..1742165 + 165 WP_224164852.1 beta family protein -
LDP65_RS26810 1742251..1742502 + 252 WP_224164853.1 hypothetical protein -
LDP65_RS26815 1742546..1743073 + 528 WP_224164938.1 beta family protein -
LDP65_RS26820 1744025..1744414 - 390 WP_224164854.1 hypothetical protein -
LDP65_RS26825 1744645..1744857 - 213 WP_224164855.1 hypothetical protein -
LDP65_RS26830 1745260..1745958 - 699 WP_224164779.1 5'-nucleotidase C-terminal domain-containing protein -
LDP65_RS26835 1745955..1746272 - 318 WP_224164781.1 hypothetical protein -
LDP65_RS26840 1746693..1747226 - 534 WP_126610250.1 GNAT family N-acetyltransferase Toxin
LDP65_RS26845 1747223..1747492 - 270 WP_126610249.1 DUF1778 domain-containing protein Antitoxin
LDP65_RS26850 1747830..1748222 - 393 WP_185829958.1 hypothetical protein -
LDP65_RS31130 1748998..1749324 - 327 WP_263422616.1 LysE family transporter -
LDP65_RS26860 1749321..1749560 - 240 WP_224164856.1 hypothetical protein -
LDP65_RS26865 1749581..1750093 - 513 WP_224164783.1 class I SAM-dependent methyltransferase -
LDP65_RS26870 1750328..1751155 + 828 WP_126607258.1 AraC family transcriptional regulator -
LDP65_RS26875 1751414..1751644 + 231 WP_126607257.1 hypothetical protein -
LDP65_RS26880 1751859..1752404 + 546 WP_224055510.1 DUF1566 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(97-153)

Antitoxin

(2-81)


Sequences


Toxin        


Download         Length: 178 a.a.        Molecular weight: 20100.41 Da        Isoelectric Point: 9.1838

>T39946 WP_126610250.1 NZ_AP025153:c1747226-1746693 [Vibrio penaeicida]
VSCGKEFVELSKLYHDRNSFDCGEQELNTFIRTQAAKHMEAGISRTMILPSAQPLLNQKFAICAFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEFQGSGLGKVSLVRALKYLWEVNHHMRAYAIVVDCLNDSAQAFYARFGFEVLCEHNG
RIRMFLAMKTVERLFNQ

Download         Length: 534 bp

>T39946 NZ_AP025153:c1747226-1746693 [Vibrio penaeicida]
GTGAGTTGTGGTAAAGAGTTTGTAGAACTTAGTAAATTATATCACGACCGAAACTCATTCGACTGTGGTGAGCAGGAGCT
AAATACATTCATCAGAACTCAAGCAGCAAAGCATATGGAAGCAGGTATTAGTCGAACAATGATTCTTCCTAGTGCTCAGC
CATTGCTTAATCAGAAGTTTGCAATATGTGCATTTTACAGTGTTGCGCCTAGTTCAATCAGTCGAGAAACCTTACCAGCG
CAACTAGCAAAGAAACTTCCTCGATATCCCATTCCAGTATTTCTTTTAGCTCAGTTAGCTGTGCATAAGGAATTTCAGGG
CTCTGGGCTAGGAAAAGTCAGTTTAGTTCGTGCACTAAAGTACCTTTGGGAAGTTAACCACCATATGAGGGCGTATGCTA
TTGTCGTGGACTGTCTGAACGATTCAGCACAGGCATTCTATGCAAGATTTGGCTTTGAAGTATTGTGTGAACATAATGGA
CGCATTCGCATGTTTCTAGCAATGAAAACGGTAGAAAGACTTTTTAACCAATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9815.21 Da        Isoelectric Point: 4.3705

>AT39946 WP_126610249.1 NZ_AP025153:c1747492-1747223 [Vibrio penaeicida]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEEHESIVVKDSVFDEFMAACDKAKAPNQALLEAA
KFTDESGIK

Download         Length: 270 bp

>AT39946 NZ_AP025153:c1747492-1747223 [Vibrio penaeicida]
ATGGCAACAGCACGTTTAGATATCCGCCTTGATGAAGAGATAAAAGCGAAAGCTGAAAAGGCATCAGCATTGCTTGGTCT
GAAAAGTTTAACTGAATATGTAGTTAGGCTTATGGACGAAGATGCAACACAGGTAATTGAAGAGCACGAAAGTATCGTGG
TTAAGGATAGTGTCTTTGACGAATTTATGGCTGCTTGTGACAAAGCAAAAGCGCCAAATCAAGCTTTGTTGGAAGCTGCA
AAATTCACAGATGAGAGCGGTATCAAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References