Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1585236..1586035 Replicon chromosome
Accession NZ_AP025150
Organism Vibrio penaeicida strain IFO 15642

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LDO91_RS25720 Protein ID WP_126610250.1
Coordinates 1585236..1585769 (-) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LDO91_RS25725 Protein ID WP_126610249.1
Coordinates 1585766..1586035 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO91_RS25695 1580534..1581607 + 1074 WP_126610255.1 beta family protein -
LDO91_RS25700 1581587..1582210 - 624 WP_126610254.1 sce7726 family protein -
LDO91_RS25705 1582561..1583397 - 837 WP_126610253.1 hypothetical protein -
LDO91_RS25710 1583391..1583798 - 408 WP_126610252.1 hypothetical protein -
LDO91_RS25715 1583801..1584865 - 1065 WP_126610251.1 hypothetical protein -
LDO91_RS25720 1585236..1585769 - 534 WP_126610250.1 GNAT family N-acetyltransferase Toxin
LDO91_RS25725 1585766..1586035 - 270 WP_126610249.1 DUF1778 domain-containing protein Antitoxin
LDO91_RS25730 1586373..1586765 - 393 WP_185829958.1 hypothetical protein -
LDO91_RS25735 1587228..1587869 - 642 WP_126610248.1 LysE family translocator -
LDO91_RS25740 1587862..1588641 - 780 WP_126610247.1 class I SAM-dependent methyltransferase -
LDO91_RS25745 1588876..1589703 + 828 WP_126607258.1 AraC family transcriptional regulator -
LDO91_RS25750 1589962..1590192 + 231 WP_126607257.1 hypothetical protein -
LDO91_RS25755 1590407..1590952 + 546 WP_224055510.1 DUF1566 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(2-81)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 20100.41 Da        Isoelectric Point: 9.1838

>T39938 WP_126610250.1 NZ_AP025150:c1585769-1585236 [Vibrio penaeicida]
VSCGKEFVELSKLYHDRNSFDCGEQELNTFIRTQAAKHMEAGISRTMILPSAQPLLNQKFAICAFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEFQGSGLGKVSLVRALKYLWEVNHHMRAYAIVVDCLNDSAQAFYARFGFEVLCEHNG
RIRMFLAMKTVERLFNQ

Download         Length: 534 bp

>T39938 NZ_AP025150:c1585769-1585236 [Vibrio penaeicida]
GTGAGTTGTGGTAAAGAGTTTGTAGAACTTAGTAAATTATATCACGACCGAAACTCATTCGACTGTGGTGAGCAGGAGCT
AAATACATTCATCAGAACTCAAGCAGCAAAGCATATGGAAGCAGGTATTAGTCGAACAATGATTCTTCCTAGTGCTCAGC
CATTGCTTAATCAGAAGTTTGCAATATGTGCATTTTACAGTGTTGCGCCTAGTTCAATCAGTCGAGAAACCTTACCAGCG
CAACTAGCAAAGAAACTTCCTCGATATCCCATTCCAGTATTTCTTTTAGCTCAGTTAGCTGTGCATAAGGAATTTCAGGG
CTCTGGGCTAGGAAAAGTCAGTTTAGTTCGTGCACTAAAGTACCTTTGGGAAGTTAACCACCATATGAGGGCGTATGCTA
TTGTCGTGGACTGTCTGAACGATTCAGCACAGGCATTCTATGCAAGATTTGGCTTTGAAGTATTGTGTGAACATAATGGA
CGCATTCGCATGTTTCTAGCAATGAAAACGGTAGAAAGACTTTTTAACCAATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9815.21 Da        Isoelectric Point: 4.3705

>AT39938 WP_126610249.1 NZ_AP025150:c1586035-1585766 [Vibrio penaeicida]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEEHESIVVKDSVFDEFMAACDKAKAPNQALLEAA
KFTDESGIK

Download         Length: 270 bp

>AT39938 NZ_AP025150:c1586035-1585766 [Vibrio penaeicida]
ATGGCAACAGCACGTTTAGATATCCGCCTTGATGAAGAGATAAAAGCGAAAGCTGAAAAGGCATCAGCATTGCTTGGTCT
GAAAAGTTTAACTGAATATGTAGTTAGGCTTATGGACGAAGATGCAACACAGGTAATTGAAGAGCACGAAAGTATCGTGG
TTAAGGATAGTGTCTTTGACGAATTTATGGCTGCTTGTGACAAAGCAAAAGCGCCAAATCAAGCTTTGTTGGAAGCTGCA
AAATTCACAGATGAGAGCGGTATCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References