Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1494081..1494880 Replicon chromosome
Accession NZ_AP025148
Organism Vibrio penaeicida strain IFO 15641

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LDO90_RS25705 Protein ID WP_126610250.1
Coordinates 1494081..1494614 (-) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LDO90_RS25710 Protein ID WP_126610249.1
Coordinates 1494611..1494880 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO90_RS25680 1489379..1490452 + 1074 WP_126610255.1 beta family protein -
LDO90_RS25685 1490432..1491055 - 624 WP_126610254.1 sce7726 family protein -
LDO90_RS25690 1491406..1492242 - 837 WP_126610253.1 hypothetical protein -
LDO90_RS25695 1492236..1492643 - 408 WP_126610252.1 hypothetical protein -
LDO90_RS25700 1492646..1493710 - 1065 WP_126610251.1 hypothetical protein -
LDO90_RS25705 1494081..1494614 - 534 WP_126610250.1 GNAT family N-acetyltransferase Toxin
LDO90_RS25710 1494611..1494880 - 270 WP_126610249.1 DUF1778 domain-containing protein Antitoxin
LDO90_RS25715 1495218..1495610 - 393 WP_185829958.1 hypothetical protein -
LDO90_RS25720 1496073..1496714 - 642 WP_126610248.1 LysE family translocator -
LDO90_RS25725 1496707..1497486 - 780 WP_126610247.1 class I SAM-dependent methyltransferase -
LDO90_RS25730 1497721..1498548 + 828 WP_126607258.1 AraC family transcriptional regulator -
LDO90_RS25735 1498807..1499037 + 231 WP_126607257.1 hypothetical protein -
LDO90_RS25740 1499252..1499797 + 546 WP_224055510.1 DUF1566 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(2-81)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 20100.41 Da        Isoelectric Point: 9.1838

>T39933 WP_126610250.1 NZ_AP025148:c1494614-1494081 [Vibrio penaeicida]
VSCGKEFVELSKLYHDRNSFDCGEQELNTFIRTQAAKHMEAGISRTMILPSAQPLLNQKFAICAFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEFQGSGLGKVSLVRALKYLWEVNHHMRAYAIVVDCLNDSAQAFYARFGFEVLCEHNG
RIRMFLAMKTVERLFNQ

Download         Length: 534 bp

>T39933 NZ_AP025148:c1494614-1494081 [Vibrio penaeicida]
GTGAGTTGTGGTAAAGAGTTTGTAGAACTTAGTAAATTATATCACGACCGAAACTCATTCGACTGTGGTGAGCAGGAGCT
AAATACATTCATCAGAACTCAAGCAGCAAAGCATATGGAAGCAGGTATTAGTCGAACAATGATTCTTCCTAGTGCTCAGC
CATTGCTTAATCAGAAGTTTGCAATATGTGCATTTTACAGTGTTGCGCCTAGTTCAATCAGTCGAGAAACCTTACCAGCG
CAACTAGCAAAGAAACTTCCTCGATATCCCATTCCAGTATTTCTTTTAGCTCAGTTAGCTGTGCATAAGGAATTTCAGGG
CTCTGGGCTAGGAAAAGTCAGTTTAGTTCGTGCACTAAAGTACCTTTGGGAAGTTAACCACCATATGAGGGCGTATGCTA
TTGTCGTGGACTGTCTGAACGATTCAGCACAGGCATTCTATGCAAGATTTGGCTTTGAAGTATTGTGTGAACATAATGGA
CGCATTCGCATGTTTCTAGCAATGAAAACGGTAGAAAGACTTTTTAACCAATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9815.21 Da        Isoelectric Point: 4.3705

>AT39933 WP_126610249.1 NZ_AP025148:c1494880-1494611 [Vibrio penaeicida]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEEHESIVVKDSVFDEFMAACDKAKAPNQALLEAA
KFTDESGIK

Download         Length: 270 bp

>AT39933 NZ_AP025148:c1494880-1494611 [Vibrio penaeicida]
ATGGCAACAGCACGTTTAGATATCCGCCTTGATGAAGAGATAAAAGCGAAAGCTGAAAAGGCATCAGCATTGCTTGGTCT
GAAAAGTTTAACTGAATATGTAGTTAGGCTTATGGACGAAGATGCAACACAGGTAATTGAAGAGCACGAAAGTATCGTGG
TTAAGGATAGTGTCTTTGACGAATTTATGGCTGCTTGTGACAAAGCAAAAGCGCCAAATCAAGCTTTGTTGGAAGCTGCA
AAATTCACAGATGAGAGCGGTATCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References