Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/ParE-YefM |
Location | 174248..174798 | Replicon | chromosome |
Accession | NZ_AP025145 | ||
Organism | Vibrio penaeicida strain IFO 15640T |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | LDO37_RS19225 | Protein ID | WP_126606873.1 |
Coordinates | 174499..174798 (+) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | LDO37_RS19220 | Protein ID | WP_126606874.1 |
Coordinates | 174248..174490 (+) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LDO37_RS19195 | 169628..170419 | - | 792 | WP_126607934.1 | 4-hydroxy-2-oxoheptanedioate aldolase | - |
LDO37_RS19200 | 170464..171267 | - | 804 | WP_101110492.1 | 2-oxo-hepta-3-ene-1,7-dioic acid hydratase | - |
LDO37_RS19205 | 171523..172032 | + | 510 | WP_224055759.1 | 4-hydroxyphenylacetate 3-monooxygenase, reductase component | - |
LDO37_RS19210 | 172083..173252 | + | 1170 | WP_126606876.1 | flavin-dependent monooxygenase | - |
LDO37_RS19215 | 173519..173752 | + | 234 | WP_126606875.1 | hypothetical protein | - |
LDO37_RS19220 | 174248..174490 | + | 243 | WP_126606874.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
LDO37_RS19225 | 174499..174798 | + | 300 | WP_126606873.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LDO37_RS19230 | 175062..177422 | + | 2361 | WP_126606872.1 | ATP-binding protein | - |
LDO37_RS19235 | 177473..179401 | - | 1929 | WP_224055760.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11534.37 Da Isoelectric Point: 9.7638
>T39925 WP_126606873.1 NZ_AP025145:174499-174798 [Vibrio penaeicida]
MPKIKYKLSKLAQSHLRKIKDYTVANYSELQWVKYKDTLLTGFRMIADNPDLGRHCDEIYPNGFYFPLGRHTAYFTKEGD
FILVVAVLGQSQLPQNHLK
MPKIKYKLSKLAQSHLRKIKDYTVANYSELQWVKYKDTLLTGFRMIADNPDLGRHCDEIYPNGFYFPLGRHTAYFTKEGD
FILVVAVLGQSQLPQNHLK
Download Length: 300 bp
>T39925 NZ_AP025145:174499-174798 [Vibrio penaeicida]
ATGCCAAAGATAAAATACAAGCTGAGTAAATTAGCTCAGAGTCACTTGCGCAAAATCAAGGACTATACTGTTGCCAATTA
TTCAGAATTACAGTGGGTAAAATACAAAGATACACTCCTTACTGGTTTTAGAATGATTGCCGACAATCCCGATCTTGGTA
GGCATTGTGATGAAATATACCCGAACGGATTCTACTTTCCTTTGGGGCGACACACGGCATACTTCACTAAAGAGGGCGAC
TTCATATTAGTTGTAGCCGTTCTTGGACAATCTCAGTTACCCCAGAACCATTTGAAATAG
ATGCCAAAGATAAAATACAAGCTGAGTAAATTAGCTCAGAGTCACTTGCGCAAAATCAAGGACTATACTGTTGCCAATTA
TTCAGAATTACAGTGGGTAAAATACAAAGATACACTCCTTACTGGTTTTAGAATGATTGCCGACAATCCCGATCTTGGTA
GGCATTGTGATGAAATATACCCGAACGGATTCTACTTTCCTTTGGGGCGACACACGGCATACTTCACTAAAGAGGGCGAC
TTCATATTAGTTGTAGCCGTTCTTGGACAATCTCAGTTACCCCAGAACCATTTGAAATAG
Antitoxin
Download Length: 81 a.a. Molecular weight: 9029.19 Da Isoelectric Point: 4.5858
>AT39925 WP_126606874.1 NZ_AP025145:174248-174490 [Vibrio penaeicida]
MYTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIKDYEELEAMKADYLKHCFESAKTDLAQNDVADGESFLNNL
MYTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIKDYEELEAMKADYLKHCFESAKTDLAQNDVADGESFLNNL
Download Length: 243 bp
>AT39925 NZ_AP025145:174248-174490 [Vibrio penaeicida]
ATGTATACATTAACGGCCAATGATGCAAAACGTAACTTCGGTGAGCTACTTCTTAATGCTCAACGTGAGCCGATAAAGAT
CAGCAAAAACAGTAAAGACGCTGTAGTAGTTATGTCCATCAAAGACTACGAAGAACTTGAAGCGATGAAGGCTGATTATC
TTAAACATTGCTTTGAGTCCGCTAAAACCGATCTAGCCCAAAACGATGTCGCTGATGGCGAAAGCTTTCTAAACAATCTG
TAA
ATGTATACATTAACGGCCAATGATGCAAAACGTAACTTCGGTGAGCTACTTCTTAATGCTCAACGTGAGCCGATAAAGAT
CAGCAAAAACAGTAAAGACGCTGTAGTAGTTATGTCCATCAAAGACTACGAAGAACTTGAAGCGATGAAGGCTGATTATC
TTAAACATTGCTTTGAGTCCGCTAAAACCGATCTAGCCCAAAACGATGTCGCTGATGGCGAAAGCTTTCTAAACAATCTG
TAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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