Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 174248..174798 Replicon chromosome
Accession NZ_AP025145
Organism Vibrio penaeicida strain IFO 15640T

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LDO37_RS19225 Protein ID WP_126606873.1
Coordinates 174499..174798 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LDO37_RS19220 Protein ID WP_126606874.1
Coordinates 174248..174490 (+) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO37_RS19195 169628..170419 - 792 WP_126607934.1 4-hydroxy-2-oxoheptanedioate aldolase -
LDO37_RS19200 170464..171267 - 804 WP_101110492.1 2-oxo-hepta-3-ene-1,7-dioic acid hydratase -
LDO37_RS19205 171523..172032 + 510 WP_224055759.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
LDO37_RS19210 172083..173252 + 1170 WP_126606876.1 flavin-dependent monooxygenase -
LDO37_RS19215 173519..173752 + 234 WP_126606875.1 hypothetical protein -
LDO37_RS19220 174248..174490 + 243 WP_126606874.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LDO37_RS19225 174499..174798 + 300 WP_126606873.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDO37_RS19230 175062..177422 + 2361 WP_126606872.1 ATP-binding protein -
LDO37_RS19235 177473..179401 - 1929 WP_224055760.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 100 a.a.        Molecular weight: 11534.37 Da        Isoelectric Point: 9.7638

>T39925 WP_126606873.1 NZ_AP025145:174499-174798 [Vibrio penaeicida]
MPKIKYKLSKLAQSHLRKIKDYTVANYSELQWVKYKDTLLTGFRMIADNPDLGRHCDEIYPNGFYFPLGRHTAYFTKEGD
FILVVAVLGQSQLPQNHLK

Download         Length: 300 bp

>T39925 NZ_AP025145:174499-174798 [Vibrio penaeicida]
ATGCCAAAGATAAAATACAAGCTGAGTAAATTAGCTCAGAGTCACTTGCGCAAAATCAAGGACTATACTGTTGCCAATTA
TTCAGAATTACAGTGGGTAAAATACAAAGATACACTCCTTACTGGTTTTAGAATGATTGCCGACAATCCCGATCTTGGTA
GGCATTGTGATGAAATATACCCGAACGGATTCTACTTTCCTTTGGGGCGACACACGGCATACTTCACTAAAGAGGGCGAC
TTCATATTAGTTGTAGCCGTTCTTGGACAATCTCAGTTACCCCAGAACCATTTGAAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9029.19 Da        Isoelectric Point: 4.5858

>AT39925 WP_126606874.1 NZ_AP025145:174248-174490 [Vibrio penaeicida]
MYTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIKDYEELEAMKADYLKHCFESAKTDLAQNDVADGESFLNNL

Download         Length: 243 bp

>AT39925 NZ_AP025145:174248-174490 [Vibrio penaeicida]
ATGTATACATTAACGGCCAATGATGCAAAACGTAACTTCGGTGAGCTACTTCTTAATGCTCAACGTGAGCCGATAAAGAT
CAGCAAAAACAGTAAAGACGCTGTAGTAGTTATGTCCATCAAAGACTACGAAGAACTTGAAGCGATGAAGGCTGATTATC
TTAAACATTGCTTTGAGTCCGCTAAAACCGATCTAGCCCAAAACGATGTCGCTGATGGCGAAAGCTTTCTAAACAATCTG
TAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References