Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 3759400..3759990 Replicon chromosome
Accession NZ_AP025032
Organism Aureimonas sp. SA4125

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag Sa4125_RS17830 Protein ID WP_224000047.1
Coordinates 3759697..3759990 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag Sa4125_RS17825 Protein ID WP_224007936.1
Coordinates 3759400..3759693 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Sa4125_RS17810 (Sa4125_35730) 3755644..3757170 + 1527 WP_224000040.1 di-heme oxidoredictase family protein -
Sa4125_RS17815 (Sa4125_35740) 3757167..3758243 + 1077 WP_224000042.1 imelysin family protein -
Sa4125_RS17820 (Sa4125_35750) 3758245..3759333 + 1089 WP_224000044.1 DUF1513 domain-containing protein -
Sa4125_RS17825 (Sa4125_35760) 3759400..3759693 - 294 WP_224007936.1 putative addiction module antidote protein Antitoxin
Sa4125_RS17830 (Sa4125_35770) 3759697..3759990 - 294 WP_224000047.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Sa4125_RS17835 (Sa4125_35780) 3760214..3760795 - 582 WP_224000053.1 sarcosine oxidase subunit gamma family protein -
Sa4125_RS17840 (Sa4125_35790) 3760788..3763787 - 3000 WP_224000055.1 sarcosine oxidase subunit alpha family protein -
Sa4125_RS17845 (Sa4125_35800) 3763784..3764167 - 384 WP_224000057.1 sarcosine oxidase subunit delta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(23-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11183.91 Da        Isoelectric Point: 9.9044

>T39920 WP_224000047.1 NZ_AP025032:c3759990-3759697 [Aureimonas sp. SA4125]
MLEIRQTRVFRDWLEALRDRRAQERIAQRLVRLQVGLFGDAKFFDGIGELRIDHGPGYRVYFARRGPILVVLLCGGDKST
QAQDIRTARALADELEI

Download         Length: 294 bp

>T39920 NZ_AP025032:c3759990-3759697 [Aureimonas sp. SA4125]
ATGCTTGAAATTCGCCAAACCCGCGTTTTCCGCGACTGGCTTGAGGCATTGCGGGACAGGCGAGCCCAGGAGCGCATCGC
TCAGCGACTCGTCCGATTGCAGGTCGGTCTTTTCGGTGATGCAAAATTCTTCGATGGCATTGGAGAACTGCGCATCGACC
ATGGACCGGGATATCGCGTCTACTTCGCCAGACGCGGACCTATCCTCGTCGTCCTGCTCTGCGGCGGCGACAAGAGCACG
CAGGCCCAGGATATCCGAACGGCCCGGGCTTTGGCGGACGAACTGGAGATTTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10113.49 Da        Isoelectric Point: 4.4645

>AT39920 WP_224007936.1 NZ_AP025032:c3759693-3759400 [Aureimonas sp. SA4125]
MPIDTLPFDASNYLGDSSAQVSLLEDAFQSGETAYIAAALGVIARARGMTQVAREAGITREALYKALSAEGDPKLSTLLG
VVRSLGLQLRAEAVSVS

Download         Length: 294 bp

>AT39920 NZ_AP025032:c3759693-3759400 [Aureimonas sp. SA4125]
ATGCCCATCGACACTCTTCCCTTCGACGCCTCAAACTATCTCGGAGACTCGTCGGCGCAGGTTTCACTGCTGGAGGATGC
TTTCCAATCCGGGGAGACCGCGTACATTGCTGCAGCGCTGGGTGTCATCGCCCGGGCGCGGGGCATGACGCAGGTGGCCA
GAGAGGCCGGCATTACGCGGGAGGCGCTTTACAAGGCGCTGAGTGCCGAAGGCGACCCCAAATTGTCGACCCTGCTCGGA
GTGGTGCGCTCACTGGGTCTGCAACTGCGCGCTGAGGCGGTGTCCGTTTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References