39919

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 2334731..2335368 Replicon chromosome
Accession NZ_AP025032
Organism Aureimonas sp. SA4125

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag Sa4125_RS10845 Protein ID WP_224007034.1
Coordinates 2335051..2335368 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag Sa4125_RS10840 Protein ID WP_224007031.1
Coordinates 2334731..2335054 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Sa4125_RS10820 (Sa4125_21700) 2329913..2331118 - 1206 WP_224007028.1 D-alanyl-D-alanine carboxypeptidase family protein -
Sa4125_RS24280 (Sa4125_21710) 2331244..2332461 - 1218 WP_275967467.1 septal ring lytic transglycosylase RlpA family protein -
Sa4125_RS10835 (Sa4125_21720) 2333097..2334734 - 1638 Protein_2150 recombinase family protein -
Sa4125_RS10840 (Sa4125_21730) 2334731..2335054 - 324 WP_224007031.1 helix-turn-helix transcriptional regulator Antitoxin
Sa4125_RS10845 (Sa4125_21740) 2335051..2335368 - 318 WP_224007034.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Sa4125_RS10850 (Sa4125_21750) 2335492..2335713 - 222 WP_224007036.1 hypothetical protein -
Sa4125_RS10855 (Sa4125_21760) 2335798..2337330 - 1533 WP_224000747.1 IS66 family transposase -
Sa4125_RS10860 (Sa4125_21770) 2337388..2337744 - 357 WP_224000737.1 IS66 family insertion sequence element accessory protein TnpB -
Sa4125_RS10865 (Sa4125_21780) 2337741..2338175 - 435 WP_224000735.1 transposase -
Sa4125_RS10870 (Sa4125_21790) 2338686..2339765 - 1080 WP_224007039.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(7-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-85)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11666.28 Da        Isoelectric Point: 10.5165

>T39919 WP_224007034.1 NZ_AP025032:c2335368-2335051 [Aureimonas sp. SA4125]
MIRGDSRSRCGGALWEAQTGGKAGWAKPLKGFSGAGVLVVVDDHDGDTYRTVYTVRFAGVVYVLRVFQKKSKHGIATPKH
DIALIEQRLKRAREDHEQWQAGRTT

Download         Length: 318 bp

>T39919 NZ_AP025032:c2335368-2335051 [Aureimonas sp. SA4125]
ATGATCCGCGGGGATTCCCGGAGCCGGTGCGGCGGGGCGCTGTGGGAGGCGCAGACCGGCGGCAAGGCAGGATGGGCCAA
GCCGCTCAAAGGGTTCAGCGGAGCGGGCGTGCTGGTGGTGGTCGATGACCATGACGGCGACACCTATCGCACTGTCTATA
CCGTTCGGTTTGCTGGCGTCGTCTACGTCCTCCGCGTCTTCCAGAAGAAGTCGAAGCACGGGATCGCGACGCCGAAGCAC
GATATCGCGCTGATCGAACAGAGATTGAAGCGAGCCAGAGAGGACCACGAACAATGGCAAGCAGGCAGGACGACATGA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11443.21 Da        Isoelectric Point: 10.7465

>AT39919 WP_224007031.1 NZ_AP025032:c2335054-2334731 [Aureimonas sp. SA4125]
MKLTEGSGNVFADLGVAEPDEELAKAQLASHIREAIKRRRLTQAAAAALVGLDQPKVSALINGRLTGFSSDRLLRCLNAL
GQDVDIVIKSPPRSGQRGRLRVVEKAA

Download         Length: 324 bp

>AT39919 NZ_AP025032:c2335054-2334731 [Aureimonas sp. SA4125]
ATGAAGTTGACGGAAGGTTCGGGCAACGTGTTCGCCGACCTTGGCGTCGCAGAACCAGATGAAGAGCTGGCGAAGGCGCA
GCTCGCCAGCCACATCCGCGAAGCGATCAAGCGCCGGAGGTTGACCCAGGCGGCAGCCGCCGCGCTGGTCGGGCTTGACC
AGCCCAAGGTGTCGGCGCTGATCAACGGTCGGCTGACAGGGTTCTCCAGCGATCGGCTGCTGCGCTGCCTCAACGCGCTC
GGGCAGGACGTGGATATCGTCATCAAATCTCCGCCCAGAAGCGGACAGCGCGGGCGGCTCCGCGTGGTGGAGAAGGCGGC
ATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References