39914

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4665766..4666282 Replicon chromosome
Accession NZ_AP025014
Organism Shewanella xiamenensis strain NUITM-VS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDO18_RS20680 Protein ID WP_220777757.1
Coordinates 4665998..4666282 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDO18_RS20675 Protein ID WP_220777758.1
Coordinates 4665766..4666008 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO18_RS20665 4662534..4663560 + 1027 WP_088585626.1 IS630-like element ISSpu8 family transposase -
LDO18_RS20670 (NUITMVS1_40510) 4664548..4664823 - 276 WP_220591404.1 hypothetical protein -
LDO18_RS20675 (NUITMVS1_40530) 4665766..4666008 + 243 WP_220777758.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LDO18_RS20680 (NUITMVS1_40540) 4665998..4666282 + 285 WP_220777757.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDO18_RS20685 (NUITMVS1_40550) 4666405..4666659 - 255 WP_220777756.1 hypothetical protein -
LDO18_RS20690 (NUITMVS1_40560) 4666755..4666955 + 201 WP_224021214.1 hypothetical protein -
LDO18_RS20695 (NUITMVS1_40570) 4666952..4667104 - 153 WP_161808794.1 hypothetical protein -
LDO18_RS20700 (NUITMVS1_40580) 4667160..4668047 - 888 WP_224021215.1 integrase domain-containing protein -
LDO18_RS20705 (NUITMVS1_40590) 4668601..4669650 - 1050 WP_224021216.1 DNA-binding protein -
LDO18_RS20710 4669855..4669998 + 144 WP_224021217.1 hypothetical protein -
LDO18_RS20715 (NUITMVS1_40610) 4670056..4670868 + 813 WP_263407381.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11154.13 Da        Isoelectric Point: 10.3015

>T39914 WP_220777757.1 NZ_AP025014:4665998-4666282 [Shewanella xiamenensis]
MTYKLEFDPRALKEWKKLGDPIRQQLKKKLAEILEHPHIEANKLRDLPDCYKIKLRTSGYRLVYQVQDERITVFVVAVGK
RERLAVYSAAEKRL

Download         Length: 285 bp

>T39914 NZ_AP025014:4665998-4666282 [Shewanella xiamenensis]
ATGACCTATAAGTTAGAGTTTGATCCCCGCGCCCTAAAGGAATGGAAGAAGCTCGGAGATCCCATCAGGCAGCAGCTAAA
AAAGAAATTGGCGGAGATACTGGAGCATCCCCATATCGAAGCAAACAAGCTCAGGGATCTCCCTGACTGTTACAAAATCA
AGTTGCGAACATCGGGATATCGCTTGGTATACCAAGTTCAAGATGAACGCATTACCGTGTTTGTCGTGGCCGTAGGCAAA
CGAGAACGCTTGGCGGTGTATTCAGCGGCAGAGAAACGCCTCTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8823.20 Da        Isoelectric Point: 4.6017

>AT39914 WP_220777758.1 NZ_AP025014:4665766-4666008 [Shewanella xiamenensis]
MGTINIRIDDELKERSFAALEKLGVSPSEALRQTLEYVATRGALPFKPVLLTADDEALITLVKERLATPRKGIEVSLDDL

Download         Length: 243 bp

>AT39914 NZ_AP025014:4665766-4666008 [Shewanella xiamenensis]
ATGGGCACAATCAACATACGCATCGATGACGAACTCAAAGAGCGTTCTTTTGCTGCATTGGAAAAATTAGGTGTAAGCCC
TTCAGAAGCATTACGCCAGACGCTTGAATATGTCGCGACAAGAGGGGCTTTACCCTTTAAGCCGGTACTGCTCACTGCCG
ATGATGAAGCCTTGATTACCTTGGTAAAAGAGCGTTTAGCGACCCCTCGCAAGGGGATCGAGGTTTCGCTCGATGACCTA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References