Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 378839..379389 Replicon chromosome
Accession NZ_AP025014
Organism Shewanella xiamenensis strain NUITM-VS1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LDO18_RS01825 Protein ID WP_224021465.1
Coordinates 378839..379138 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LDO18_RS01830 Protein ID WP_224021466.1
Coordinates 379147..379389 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO18_RS01800 (NUITMVS1_03480) 373875..374450 - 576 WP_037423247.1 XRE family transcriptional regulator -
LDO18_RS01805 (NUITMVS1_03490) 374574..375761 + 1188 WP_224022103.1 benzoate/H(+) symporter BenE family transporter -
LDO18_RS01810 (NUITMVS1_03500) 375819..376295 - 477 WP_224021462.1 GNAT family N-acetyltransferase -
LDO18_RS01815 (NUITMVS1_03510) 376773..378281 + 1509 WP_224021463.1 P-loop NTPase fold protein -
LDO18_RS01820 378499..378789 + 291 WP_224021464.1 hypothetical protein -
LDO18_RS01825 (NUITMVS1_03520) 378839..379138 - 300 WP_224021465.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDO18_RS01830 (NUITMVS1_03530) 379147..379389 - 243 WP_224021466.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LDO18_RS01835 (NUITMVS1_03540) 379574..380317 - 744 WP_224021467.1 hypothetical protein -
LDO18_RS01840 (NUITMVS1_03550) 380328..381590 - 1263 WP_224021468.1 beta-ketoacyl-ACP synthase -
LDO18_RS01845 (NUITMVS1_03560) 381591..382316 - 726 WP_172588042.1 3-ketoacyl-ACP reductase FabG2 -
LDO18_RS01850 (NUITMVS1_03570) 382417..382959 - 543 WP_224021469.1 hotdog family protein -
LDO18_RS01855 (NUITMVS1_03580) 382965..384182 - 1218 WP_224021470.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-64)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11607.38 Da        Isoelectric Point: 9.6273

>T39907 WP_224021465.1 NZ_AP025014:c379138-378839 [Shewanella xiamenensis]
MNNKRYKLSRLAQTHLLKIKDYTLQHVSESQWHKYKESLISGLQMLANNPELGRSCHDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQHHLK

Download         Length: 300 bp

>T39907 NZ_AP025014:c379138-378839 [Shewanella xiamenensis]
ATGAATAATAAACGCTATAAACTGAGTAGGTTAGCTCAGACTCACCTACTAAAGATTAAAGACTACACCCTTCAACACGT
TTCTGAGTCGCAGTGGCACAAATATAAAGAAAGCCTTATCTCCGGTTTGCAAATGTTAGCCAATAACCCCGAATTAGGCA
GAAGCTGCCACGATATTTATCCCAACGGTTTCTACTTTCCTATCGGTAAACACACCGCCTACTTCACCAAAGAAGACGAC
TTTATCCTTATCGTTGCCCTGTTAGGTCAACCACAGCTACCCCAACATCATCTGAAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8954.18 Da        Isoelectric Point: 5.0621

>AT39907 WP_224021466.1 NZ_AP025014:c379389-379147 [Shewanella xiamenensis]
MQTITANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Download         Length: 243 bp

>AT39907 NZ_AP025014:c379389-379147 [Shewanella xiamenensis]
ATGCAAACAATAACCGCCAATGACGCCAAACGAAATTTCGGTGAGTTGCTGCTAAACGCTCAACGTGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTGGTCATGTCTATCCACGATTACGAACAGCTTGAGGCGATGAAAGCCGACTATC
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCAAAGGGCAATGTGGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References