Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2437871..2438784 | Replicon | chromosome |
| Accession | NZ_AP025009 | ||
| Organism | Raoultella ornithinolytica strain NUITM-VR1 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | LDO46_RS11400 | Protein ID | WP_069475889.1 |
| Coordinates | 2437871..2438344 (-) | Length | 158 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A808Y7A4 |
| Locus tag | LDO46_RS11405 | Protein ID | WP_004862777.1 |
| Coordinates | 2438341..2438784 (-) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LDO46_RS11375 (NUITMVR1_22420) | 2433910..2434518 | - | 609 | WP_069475887.1 | glutathione S-transferase family protein | - |
| LDO46_RS11380 (NUITMVR1_22430) | 2434760..2435665 | + | 906 | WP_032716408.1 | transcriptional regulator GcvA | - |
| LDO46_RS11385 (NUITMVR1_22440) | 2435693..2436598 | - | 906 | WP_044349852.1 | LysR family transcriptional regulator | - |
| LDO46_RS11390 (NUITMVR1_22450) | 2436701..2437018 | + | 318 | WP_048025224.1 | nuclear transport factor 2 family protein | - |
| LDO46_RS11395 (NUITMVR1_22460) | 2437011..2437790 | + | 780 | WP_118860327.1 | SDR family oxidoreductase | - |
| LDO46_RS11400 (NUITMVR1_22470) | 2437871..2438344 | - | 474 | WP_069475889.1 | RES domain-containing protein | Toxin |
| LDO46_RS11405 (NUITMVR1_22480) | 2438341..2438784 | - | 444 | WP_004862777.1 | DUF2384 domain-containing protein | Antitoxin |
| LDO46_RS11410 (NUITMVR1_22490) | 2438974..2439540 | - | 567 | WP_015584190.1 | DJ-1/PfpI family protein | - |
| LDO46_RS11415 (NUITMVR1_22500) | 2439938..2440720 | + | 783 | WP_032717546.1 | DUF3750 domain-containing protein | - |
| LDO46_RS11420 (NUITMVR1_22510) | 2440917..2442140 | + | 1224 | WP_048025269.1 | zinc metallochaperone GTPase ZigA | - |
| LDO46_RS11440 (NUITMVR1_22520) | 2443070..2443546 | - | 477 | WP_118860326.1 | acid resistance repetitive basic protein Asr | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 158 a.a. Molecular weight: 17540.86 Da Isoelectric Point: 4.8081
>T39896 WP_069475889.1 NZ_AP025009:c2438344-2437871 [Raoultella ornithinolytica]
MIFYRLVTGRYASEAWTGSGANQYGGRWNHQGHPAVYVSTSIALASLEILVHVKNEAILNQYQLYSIEIPDSEVESLDKQ
WLPDNWQENPMPVSTMDLGTGWLQSGSGLALMLPSCIIPYENNAILNPLHPAFSEALASVRQYPFTFDPRLARSTLL
MIFYRLVTGRYASEAWTGSGANQYGGRWNHQGHPAVYVSTSIALASLEILVHVKNEAILNQYQLYSIEIPDSEVESLDKQ
WLPDNWQENPMPVSTMDLGTGWLQSGSGLALMLPSCIIPYENNAILNPLHPAFSEALASVRQYPFTFDPRLARSTLL
Download Length: 474 bp
>T39896 NZ_AP025009:c2438344-2437871 [Raoultella ornithinolytica]
ATGATTTTCTATCGTCTGGTTACCGGCCGTTACGCCAGCGAAGCCTGGACGGGAAGCGGGGCCAACCAGTACGGCGGGCG
CTGGAATCACCAGGGACACCCGGCGGTCTATGTGTCCACTTCCATTGCCCTGGCGTCACTGGAGATCCTGGTTCACGTCA
AAAATGAGGCAATCCTCAACCAGTATCAGCTGTATAGTATCGAGATACCGGACAGTGAAGTGGAATCCCTCGATAAACAG
TGGTTACCGGATAACTGGCAAGAAAATCCGATGCCCGTTTCCACAATGGATCTGGGCACCGGCTGGCTACAGTCGGGCAG
CGGTCTGGCGCTGATGCTTCCCTCCTGCATTATTCCCTATGAAAACAACGCCATTTTAAACCCGCTGCATCCCGCGTTCA
GCGAGGCCCTGGCCTCCGTGCGTCAGTATCCCTTTACCTTTGATCCCCGCCTCGCACGCTCCACGCTCCTCTGA
ATGATTTTCTATCGTCTGGTTACCGGCCGTTACGCCAGCGAAGCCTGGACGGGAAGCGGGGCCAACCAGTACGGCGGGCG
CTGGAATCACCAGGGACACCCGGCGGTCTATGTGTCCACTTCCATTGCCCTGGCGTCACTGGAGATCCTGGTTCACGTCA
AAAATGAGGCAATCCTCAACCAGTATCAGCTGTATAGTATCGAGATACCGGACAGTGAAGTGGAATCCCTCGATAAACAG
TGGTTACCGGATAACTGGCAAGAAAATCCGATGCCCGTTTCCACAATGGATCTGGGCACCGGCTGGCTACAGTCGGGCAG
CGGTCTGGCGCTGATGCTTCCCTCCTGCATTATTCCCTATGAAAACAACGCCATTTTAAACCCGCTGCATCCCGCGTTCA
GCGAGGCCCTGGCCTCCGTGCGTCAGTATCCCTTTACCTTTGATCCCCGCCTCGCACGCTCCACGCTCCTCTGA
Antitoxin
Download Length: 148 a.a. Molecular weight: 16190.45 Da Isoelectric Point: 4.9405
>AT39896 WP_004862777.1 NZ_AP025009:c2438784-2438341 [Raoultella ornithinolytica]
MKTWVPAEQPADNALWRYAGLPANRGMQLIELLSMGLPVSILDNIHEWTEMSKTDILRITGINERNVARRKSAGGTLTPG
ESERVARFVRVLDTAVDYFGSKQDAYDWLQSPVRGLGNVAPIDLIATESGALEVTDLIGRLEHGVFA
MKTWVPAEQPADNALWRYAGLPANRGMQLIELLSMGLPVSILDNIHEWTEMSKTDILRITGINERNVARRKSAGGTLTPG
ESERVARFVRVLDTAVDYFGSKQDAYDWLQSPVRGLGNVAPIDLIATESGALEVTDLIGRLEHGVFA
Download Length: 444 bp
>AT39896 NZ_AP025009:c2438784-2438341 [Raoultella ornithinolytica]
ATGAAAACCTGGGTTCCTGCAGAGCAACCTGCCGATAATGCGCTGTGGCGCTATGCCGGGCTACCGGCGAATCGGGGTAT
GCAGTTGATTGAGCTGCTGAGTATGGGATTACCGGTCAGCATTCTGGATAATATTCATGAGTGGACGGAAATGTCGAAAA
CCGACATTCTGCGCATCACCGGGATTAATGAGCGCAACGTTGCCCGGCGCAAGAGCGCGGGCGGCACGTTGACGCCAGGC
GAAAGCGAACGTGTGGCGCGTTTTGTCAGGGTCCTGGATACCGCCGTCGACTATTTTGGCAGCAAGCAGGATGCCTACGA
CTGGCTGCAGTCGCCGGTCAGAGGACTGGGCAATGTCGCCCCCATCGACCTGATTGCTACCGAGAGCGGCGCGCTGGAAG
TAACAGACCTGATTGGTCGCCTGGAACACGGCGTCTTTGCATGA
ATGAAAACCTGGGTTCCTGCAGAGCAACCTGCCGATAATGCGCTGTGGCGCTATGCCGGGCTACCGGCGAATCGGGGTAT
GCAGTTGATTGAGCTGCTGAGTATGGGATTACCGGTCAGCATTCTGGATAATATTCATGAGTGGACGGAAATGTCGAAAA
CCGACATTCTGCGCATCACCGGGATTAATGAGCGCAACGTTGCCCGGCGCAAGAGCGCGGGCGGCACGTTGACGCCAGGC
GAAAGCGAACGTGTGGCGCGTTTTGTCAGGGTCCTGGATACCGCCGTCGACTATTTTGGCAGCAAGCAGGATGCCTACGA
CTGGCTGCAGTCGCCGGTCAGAGGACTGGGCAATGTCGCCCCCATCGACCTGATTGCTACCGAGAGCGGCGCGCTGGAAG
TAACAGACCTGATTGGTCGCCTGGAACACGGCGTCTTTGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|