Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FaRel2-ATfaRel2/-
Location 1627424..1628264 Replicon chromosome
Accession NZ_AP024966
Organism Megamonas funiformis strain 1CBH44

Toxin (Protein)


Gene name faRel2 Uniprot ID -
Locus tag LDM97_RS07815 Protein ID WP_224169135.1
Coordinates 1627424..1628044 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name ATfaRel2 Uniprot ID -
Locus tag LDM97_RS07820 Protein ID WP_224169136.1
Coordinates 1628025..1628264 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDM97_RS07805 (MU1CBH_15230) 1622919..1624058 + 1140 WP_224169133.1 restriction endonuclease subunit S -
LDM97_RS07810 (MU1CBH_15240) 1624081..1627101 - 3021 WP_224169134.1 metallophosphoesterase -
LDM97_RS07815 (MU1CBH_15250) 1627424..1628044 + 621 WP_224169135.1 hypothetical protein Toxin
LDM97_RS07820 (MU1CBH_15260) 1628025..1628264 + 240 WP_224169136.1 hypothetical protein Antitoxin
LDM97_RS07825 (MU1CBH_15270) 1628596..1629555 + 960 WP_224169137.1 DUF2971 domain-containing protein -
LDM97_RS07830 (MU1CBH_15280) 1629589..1630089 + 501 WP_224169138.1 O-acetyl-ADP-ribose deacetylase -
LDM97_RS07835 (MU1CBH_15290) 1630380..1632047 + 1668 WP_018999798.1 SulP family inorganic anion transporter -
LDM97_RS07840 (MU1CBH_15300) 1632123..1632890 - 768 WP_224169139.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(67-171)

Antitoxin

Protein of unknown function DUF6718

(1-74)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 24669.96 Da        Isoelectric Point: 7.9265

>T39867 WP_224169135.1 NZ_AP024966:1627424-1628044 [Megamonas funiformis]
MINYDILKKDGLTIELLTSLSFKSKLNHSLKRTLRHFDKQAIFKELQEVNEWYDLNENLHDILIDYRIKSLQSAYQKYHR
YPLNRPLAKVFNDLLGFRTLCDNYEDILSLSQDSNIYIVDMSKGKSNDDGYRGVHIYFQLSNYHYPIEVQYNTYYDRQLN
NWLHKYVYKKNFPNSIGITLREKYEQGCIQNETIFKEVLSHVLSNS

Download         Length: 621 bp

>T39867 NZ_AP024966:1627424-1628044 [Megamonas funiformis]
ATGATAAATTATGATATTCTAAAAAAAGATGGATTAACAATCGAATTATTAACTAGCTTATCATTCAAATCTAAATTAAA
TCATAGTTTAAAAAGAACTTTAAGACATTTTGATAAACAAGCTATATTTAAAGAATTACAGGAAGTAAACGAATGGTATG
ATTTAAATGAAAATCTACATGATATCTTAATTGATTACAGAATCAAAAGTTTACAATCTGCTTATCAGAAATATCATAGA
TATCCCTTAAATCGACCTTTAGCTAAAGTTTTTAATGATTTACTAGGTTTTAGAACTTTATGCGATAATTACGAAGATAT
TTTATCTTTATCTCAAGATTCTAATATTTATATTGTTGATATGTCTAAAGGAAAATCTAATGACGATGGATATAGAGGTG
TTCATATTTATTTTCAACTTAGTAATTATCATTACCCTATAGAAGTACAATACAACACCTATTATGATAGACAATTAAAT
AATTGGCTTCATAAATATGTTTATAAAAAAAATTTTCCTAATTCTATAGGTATTACTCTTAGAGAAAAATATGAACAAGG
ATGTATTCAAAACGAAACAATATTTAAGGAGGTTTTATCTCATGTGTTATCTAATAGCTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9063.37 Da        Isoelectric Point: 7.9632

>AT39867 WP_224169136.1 NZ_AP024966:1628025-1628264 [Megamonas funiformis]
MCYLIAKDFNSIGSIALQTNHGKKLVDLKKKILSVIGYDNIQLVTISRPSAYGEYEPYSFANSEKDFEEKVYDMYNKSK

Download         Length: 240 bp

>AT39867 NZ_AP024966:1628025-1628264 [Megamonas funiformis]
ATGTGTTATCTAATAGCTAAAGATTTTAATAGTATTGGTTCTATTGCCCTGCAAACTAATCATGGTAAAAAATTAGTAGA
TTTAAAAAAGAAAATTCTTTCTGTAATAGGTTATGATAATATTCAATTAGTAACAATTAGTAGACCTTCTGCTTACGGAG
AATATGAACCTTATTCATTTGCTAACTCTGAGAAAGATTTTGAAGAGAAAGTTTATGATATGTATAATAAAAGTAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References