Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 808832..809181 Replicon chromosome
Accession NZ_AP024958
Organism Paraburkholderia terrae strain KU-64

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PTKU64_RS44665 Protein ID WP_229517454.1
Coordinates 809071..809181 (+) Length 37 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A7Z7FNP7
Locus tag PTKU64_RS44660 Protein ID WP_009770832.1
Coordinates 808832..809074 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTKU64_RS44640 (PTKU64_89250) 804164..805558 + 1395 WP_091788751.1 replication initiation protein -
PTKU64_RS44645 (PTKU64_89260) 805849..806211 - 363 WP_229517448.1 hypothetical protein -
PTKU64_RS44650 (PTKU64_89280) 807582..807926 + 345 WP_229517450.1 hypothetical protein -
PTKU64_RS44655 (PTKU64_89290) 808244..808534 + 291 WP_229517452.1 hypothetical protein -
PTKU64_RS44660 (PTKU64_89300) 808832..809074 + 243 WP_009770832.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PTKU64_RS44665 809071..809181 + 111 WP_229517454.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PTKU64_RS44670 (PTKU64_89310) 809178..809372 + 195 WP_229517455.1 type II toxin-antitoxin system RelE/ParE family toxin -
PTKU64_RS44675 (PTKU64_89330) 810136..810528 + 393 WP_229517457.1 hypothetical protein -
PTKU64_RS44680 (PTKU64_89340) 810596..810928 - 333 WP_229517459.1 H-NS family nucleoid-associated regulatory protein -
PTKU64_RS44685 (PTKU64_89360) 811735..812583 - 849 WP_229517461.1 ABC transporter ATP-binding protein -
PTKU64_RS44690 (PTKU64_89370) 812586..813881 - 1296 WP_229517898.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 4209.68 Da        Isoelectric Point: 3.8570

>T39855 WP_229517454.1 NZ_AP024958:809071-809181 [Paraburkholderia terrae]
VKEFVLSPAAELDLDDIWDYSVENWGIRQAERYIPA

Download         Length: 111 bp

>T39855 NZ_AP024958:809071-809181 [Paraburkholderia terrae]
GTGAAGGAGTTTGTTCTTTCGCCGGCGGCCGAGCTGGATCTCGATGATATTTGGGACTATTCGGTAGAAAACTGGGGGAT
CCGGCAGGCAGAGCGCTATATCCCCGCATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8942.04 Da        Isoelectric Point: 8.6373

>AT39855 WP_009770832.1 NZ_AP024958:808832-809074 [Paraburkholderia terrae]
MGKNTSVSLGDHFAEFVEDRVRAGRYNTASDVVRAGLRLLEEQEAKLDALRVELEKGERSGPSRPFDFDAFLARKKKSAT

Download         Length: 243 bp

>AT39855 NZ_AP024958:808832-809074 [Paraburkholderia terrae]
ATGGGCAAAAACACCTCCGTTTCGCTCGGCGACCACTTCGCCGAGTTTGTCGAAGATCGCGTGCGTGCCGGTCGCTACAA
CACGGCGAGCGATGTGGTTCGGGCTGGCCTGCGTTTGCTGGAGGAACAGGAAGCAAAACTCGATGCTCTACGCGTCGAGC
TGGAGAAAGGCGAGCGCTCGGGTCCGTCGAGGCCGTTTGACTTCGACGCGTTTCTCGCACGCAAGAAGAAGTCCGCGACG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7FNP7

References