Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 796150..796811 Replicon chromosome
Accession NZ_AP024958
Organism Paraburkholderia terrae strain KU-64

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PTKU64_RS44615 Protein ID WP_091788766.1
Coordinates 796150..796581 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PTKU64_RS44620 Protein ID WP_229517446.1
Coordinates 796581..796811 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTKU64_RS44600 (PTKU64_89150) 792230..793222 - 993 WP_229517441.1 substrate-binding domain-containing protein -
PTKU64_RS44605 (PTKU64_89160) 793337..794506 + 1170 WP_229517442.1 LacI family DNA-binding transcriptional regulator -
PTKU64_RS44610 (PTKU64_89170) 794795..795301 - 507 WP_229517444.1 hypothetical protein -
PTKU64_RS44615 (PTKU64_89180) 796150..796581 - 432 WP_091788766.1 PIN domain-containing protein Toxin
PTKU64_RS44620 (PTKU64_89190) 796581..796811 - 231 WP_229517446.1 CopG family transcriptional regulator Antitoxin
PTKU64_RS47345 (PTKU64_89200) 797047..797181 - 135 WP_276314549.1 hypothetical protein -
PTKU64_RS44625 (PTKU64_89220) 798593..799897 - 1305 WP_114224478.1 group II intron reverse transcriptase/maturase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15605.73 Da        Isoelectric Point: 5.7708

>T39854 WP_091788766.1 NZ_AP024958:c796581-796150 [Paraburkholderia terrae]
MTYLLDVNVLIALLDAGHVQHEAAHEWFGRAGHAAWATCPLTENGVLRIIGNPRYPNTLETPAAVAPLVAQLRAHPGHAF
WSDDLSMLDPEYVDLNRVLATDQVTDTYLLALARRHGGALATFDRRLVADAVPDGARHLELIG

Download         Length: 432 bp

>T39854 NZ_AP024958:c796581-796150 [Paraburkholderia terrae]
ATGACTTATCTGCTTGACGTCAACGTACTGATTGCGCTGCTCGACGCGGGCCACGTACAGCACGAGGCCGCGCACGAATG
GTTCGGCCGGGCAGGGCACGCCGCTTGGGCGACCTGCCCGCTGACCGAAAACGGCGTGCTGCGCATCATCGGCAATCCGC
GCTACCCGAACACACTGGAGACGCCGGCCGCGGTCGCGCCGCTCGTCGCGCAACTTCGAGCACATCCTGGCCACGCCTTC
TGGTCTGACGACCTGAGCATGCTCGATCCGGAGTATGTTGACTTGAACCGCGTCCTCGCGACCGACCAGGTGACCGACAC
GTACCTGCTCGCCCTCGCGCGCCGCCATGGAGGGGCGCTGGCCACCTTCGACCGCCGGCTGGTCGCCGATGCGGTGCCCG
ACGGTGCGCGCCACCTCGAACTCATTGGTTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8280.48 Da        Isoelectric Point: 11.5000

>AT39854 WP_229517446.1 NZ_AP024958:c796811-796581 [Paraburkholderia terrae]
MRTTLDIDDDVLALARARADREHVSIGRIISQLARAALQRPAVAPATRNGLPVLPNARTARTVTPEVVNQMRDEAP

Download         Length: 231 bp

>AT39854 NZ_AP024958:c796811-796581 [Paraburkholderia terrae]
ATGCGAACCACCCTAGATATCGACGACGACGTGCTCGCCCTCGCACGCGCGCGCGCCGACCGCGAGCACGTGTCGATCGG
TCGCATCATCTCGCAACTCGCGCGCGCGGCGCTGCAGCGTCCCGCAGTCGCTCCGGCCACGCGCAACGGCTTGCCGGTGC
TGCCGAACGCGCGCACCGCGCGCACGGTCACGCCTGAAGTCGTCAACCAGATGCGCGACGAGGCGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References