Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 13686..14695 | Replicon | chromosome |
| Accession | NZ_AP024958 | ||
| Organism | Paraburkholderia terrae strain KU-64 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | PTKU64_RS40670 | Protein ID | WP_229517517.1 |
| Coordinates | 13686..14162 (-) | Length | 159 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | A0A2I8F4P3 |
| Locus tag | PTKU64_RS40675 | Protein ID | WP_052426841.1 |
| Coordinates | 14159..14695 (-) | Length | 179 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PTKU64_RS40640 (PTKU64_80630) | 8802..9167 | + | 366 | WP_229517512.1 | hypothetical protein | - |
| PTKU64_RS40645 (PTKU64_80640) | 9177..9359 | + | 183 | WP_229517513.1 | hypothetical protein | - |
| PTKU64_RS40650 | 10751..11562 | + | 812 | WP_094297401.1 | IS5 family transposase | - |
| PTKU64_RS40655 (PTKU64_80700) | 11944..12180 | - | 237 | WP_229517514.1 | hypothetical protein | - |
| PTKU64_RS40660 (PTKU64_80710) | 12223..12669 | - | 447 | WP_229517515.1 | hypothetical protein | - |
| PTKU64_RS40665 (PTKU64_80720) | 12701..13219 | - | 519 | WP_229517516.1 | hypothetical protein | - |
| PTKU64_RS40670 (PTKU64_80730) | 13686..14162 | - | 477 | WP_229517517.1 | RES family NAD+ phosphorylase | Toxin |
| PTKU64_RS40675 (PTKU64_80740) | 14159..14695 | - | 537 | WP_052426841.1 | DUF2384 domain-containing protein | Antitoxin |
| PTKU64_RS40680 | 15361..16476 | + | 1116 | Protein_19 | diguanylate cyclase | - |
| PTKU64_RS40685 (PTKU64_80770) | 16492..16773 | - | 282 | WP_229517849.1 | hypothetical protein | - |
| PTKU64_RS40690 (PTKU64_80780) | 17097..17339 | + | 243 | WP_036001467.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| PTKU64_RS40695 (PTKU64_80790) | 17339..17659 | + | 321 | WP_229517518.1 | CcdB family protein | - |
| PTKU64_RS40700 (PTKU64_80800) | 17795..18142 | + | 348 | WP_229517519.1 | hypothetical protein | - |
| PTKU64_RS47305 (PTKU64_80820) | 18890..19024 | - | 135 | WP_276314550.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 159 a.a. Molecular weight: 17132.73 Da Isoelectric Point: 7.8490
>T39853 WP_229517517.1 NZ_AP024958:c14162-13686 [Paraburkholderia terrae]
VTVAVWRIATEAPNYPADDLSGAGAKVTGGRWNRRGTPVLYCASTIALACLETVVHIRAAGLPLNRYLVRLDVPDNVWQA
AMVFTNISAPIGWDAIPPGMTSLDTGEKWIYNAATALLLVPSVIVPEETNVLINPAHPDAAGIRAQKVRRWTYDQRMG
VTVAVWRIATEAPNYPADDLSGAGAKVTGGRWNRRGTPVLYCASTIALACLETVVHIRAAGLPLNRYLVRLDVPDNVWQA
AMVFTNISAPIGWDAIPPGMTSLDTGEKWIYNAATALLLVPSVIVPEETNVLINPAHPDAAGIRAQKVRRWTYDQRMG
Download Length: 477 bp
>T39853 NZ_AP024958:c14162-13686 [Paraburkholderia terrae]
GTGACGGTCGCGGTCTGGCGGATCGCGACCGAAGCGCCCAACTACCCCGCAGACGATCTTTCCGGTGCCGGCGCGAAGGT
GACGGGTGGCCGGTGGAACCGGCGCGGAACGCCGGTTTTGTACTGTGCGTCGACCATCGCCCTGGCCTGTCTGGAAACCG
TGGTTCACATTCGCGCGGCGGGATTGCCGCTGAACCGCTACCTCGTTCGTCTGGACGTGCCCGACAACGTCTGGCAGGCC
GCGATGGTTTTCACGAACATCTCGGCGCCCATCGGATGGGACGCAATCCCGCCCGGCATGACGAGCCTGGATACAGGTGA
GAAATGGATCTATAACGCCGCCACCGCCCTGCTTCTTGTGCCGTCCGTCATCGTCCCGGAGGAGACGAACGTCCTCATCA
ACCCGGCACATCCGGATGCCGCGGGTATTCGTGCACAGAAAGTACGGCGCTGGACCTACGATCAGCGAATGGGTTAA
GTGACGGTCGCGGTCTGGCGGATCGCGACCGAAGCGCCCAACTACCCCGCAGACGATCTTTCCGGTGCCGGCGCGAAGGT
GACGGGTGGCCGGTGGAACCGGCGCGGAACGCCGGTTTTGTACTGTGCGTCGACCATCGCCCTGGCCTGTCTGGAAACCG
TGGTTCACATTCGCGCGGCGGGATTGCCGCTGAACCGCTACCTCGTTCGTCTGGACGTGCCCGACAACGTCTGGCAGGCC
GCGATGGTTTTCACGAACATCTCGGCGCCCATCGGATGGGACGCAATCCCGCCCGGCATGACGAGCCTGGATACAGGTGA
GAAATGGATCTATAACGCCGCCACCGCCCTGCTTCTTGTGCCGTCCGTCATCGTCCCGGAGGAGACGAACGTCCTCATCA
ACCCGGCACATCCGGATGCCGCGGGTATTCGTGCACAGAAAGTACGGCGCTGGACCTACGATCAGCGAATGGGTTAA
Antitoxin
Download Length: 179 a.a. Molecular weight: 19187.98 Da Isoelectric Point: 10.3478
>AT39853 WP_052426841.1 NZ_AP024958:c14695-14159 [Paraburkholderia terrae]
VNAPATSARRPARKAAVRLPAKPAAPSRAAKVHATKINDYLTLYHAPPLERISFIKHGVDAHDVYVLARNMGTSQDNLMV
TLGLPRSTIIRKAKGKARLSAEQSERVIGMARLVGQVEAMVAESGDPAGFDAAHWVNEWLDQPNPALDQRRPAEFMDTVA
GQEFVAALLAKAQSGAYA
VNAPATSARRPARKAAVRLPAKPAAPSRAAKVHATKINDYLTLYHAPPLERISFIKHGVDAHDVYVLARNMGTSQDNLMV
TLGLPRSTIIRKAKGKARLSAEQSERVIGMARLVGQVEAMVAESGDPAGFDAAHWVNEWLDQPNPALDQRRPAEFMDTVA
GQEFVAALLAKAQSGAYA
Download Length: 537 bp
>AT39853 NZ_AP024958:c14695-14159 [Paraburkholderia terrae]
GTGAACGCGCCCGCCACCTCCGCCCGTCGCCCGGCCCGCAAGGCTGCAGTTCGTCTCCCGGCAAAACCCGCCGCGCCGTC
GCGGGCCGCCAAAGTGCATGCGACGAAGATCAACGACTACCTCACCCTCTATCACGCGCCTCCGCTCGAGCGCATCAGCT
TCATCAAGCACGGTGTGGATGCCCACGACGTGTACGTTCTTGCGCGCAACATGGGAACCTCGCAGGATAATCTGATGGTG
ACCTTGGGGTTGCCGCGCTCGACCATCATCCGTAAGGCCAAGGGGAAGGCGCGCCTGTCCGCGGAGCAGAGCGAACGGGT
GATCGGTATGGCAAGGCTGGTCGGCCAGGTCGAAGCGATGGTCGCGGAATCCGGTGATCCGGCAGGCTTCGACGCCGCCC
ACTGGGTGAACGAATGGCTGGACCAGCCCAACCCGGCACTGGATCAACGCCGTCCTGCCGAGTTCATGGATACGGTCGCG
GGACAGGAATTTGTCGCTGCCCTGCTGGCGAAGGCACAGAGCGGAGCGTATGCGTGA
GTGAACGCGCCCGCCACCTCCGCCCGTCGCCCGGCCCGCAAGGCTGCAGTTCGTCTCCCGGCAAAACCCGCCGCGCCGTC
GCGGGCCGCCAAAGTGCATGCGACGAAGATCAACGACTACCTCACCCTCTATCACGCGCCTCCGCTCGAGCGCATCAGCT
TCATCAAGCACGGTGTGGATGCCCACGACGTGTACGTTCTTGCGCGCAACATGGGAACCTCGCAGGATAATCTGATGGTG
ACCTTGGGGTTGCCGCGCTCGACCATCATCCGTAAGGCCAAGGGGAAGGCGCGCCTGTCCGCGGAGCAGAGCGAACGGGT
GATCGGTATGGCAAGGCTGGTCGGCCAGGTCGAAGCGATGGTCGCGGAATCCGGTGATCCGGCAGGCTTCGACGCCGCCC
ACTGGGTGAACGAATGGCTGGACCAGCCCAACCCGGCACTGGATCAACGCCGTCCTGCCGAGTTCATGGATACGGTCGCG
GGACAGGAATTTGTCGCTGCCCTGCTGGCGAAGGCACAGAGCGGAGCGTATGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|