Detailed information of TA system TA039831

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YefM(antitoxin)
• Location: 2188933..2189501
• Replicon: chromosome
• Accession: NZ_AP024907
• Organism: Vibrio spartinae strain CECT 9026

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1N6M071
• Locus tag: OCU60_RS09660
• Protein ID: WP_038179721.1
• Coordinates: 2188933..2189223 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCU60_RS09665
• Protein ID: WP_072961590.1
• Coordinates: 2189220..2189501 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU60_RS09630	2183937..2185043	+	1107	WP_074372666.1	threonine-phosphate decarboxylase CobD	-
OCU60_RS09635	2185047..2185601	-	555	WP_074372667.1	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	-
OCU60_RS09640	2185805..2186269	-	465	WP_261854720.1	acyltransferase	-
OCU60_RS09645	2186584..2186988	-	405	WP_074371393.1	hypothetical protein	-
OCU60_RS09650	2187011..2187352	+	342	WP_074371394.1	hypothetical protein	-
OCU60_RS09655	2187786..2188001	-	216	WP_139302089.1	hypothetical protein	-
OCU60_RS09660	2188933..2189223	-	291	WP_038179721.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCU60_RS09665	2189220..2189501	-	282	WP_072961590.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCU60_RS09670	2189814..2190152	+	339	WP_074371396.1	hypothetical protein	-
OCU60_RS09675	2190604..2191482	-	879	WP_074371397.1	HEPN domain-containing protein	-
OCU60_RS09680	2191675..2192127	-	453	WP_083602561.1	hypothetical protein	-
OCU60_RS09685	2192534..2192995	-	462	Protein_1900	S-type pyocin domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-75)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11004.68 Da
• Isoelectric Point: 4.3313

>T39831 WP_038179721.1 NZ_AP024907:c2189223-2188933 [Vibrio spartinae]
MNVVWAPFALEKLGDAAEFISLDDPVAAENWVNDVFDKTELLGTMPEMGRVVPELPNTNYREIIFGHYRIIYSCSIEIRI
LTVRNCRQILTKDDVC

Nucleotide

• Length: 291 bp

>T39831 NZ_AP024907:c2189223-2188933 [Vibrio spartinae]
ATGAATGTTGTTTGGGCGCCATTCGCTCTTGAAAAATTAGGGGATGCGGCAGAATTTATTTCGTTAGACGATCCTGTAGC
AGCAGAAAATTGGGTTAATGATGTTTTTGATAAAACGGAATTATTAGGAACTATGCCTGAAATGGGGAGAGTTGTTCCCG
AGCTGCCGAATACGAACTATCGAGAAATTATCTTTGGTCACTACCGTATTATTTATAGTTGTTCTATTGAGATACGGATA
CTCACAGTAAGAAATTGCCGTCAGATATTAACAAAAGATGACGTATGCTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10577.20 Da
• Isoelectric Point: 6.3999

>AT39831 WP_072961590.1 NZ_AP024907:c2189501-2189220 [Vibrio spartinae]
MKRIRFDQDIKPLSEFRSGVASFIKQINETRRPLVITQRGKGVAVVLDVEEYEAMQEKIELLEEMRAAEAQLASGMGVSN
EDARANVLERIKK

Nucleotide

• Length: 282 bp

>AT39831 NZ_AP024907:c2189501-2189220 [Vibrio spartinae]
ATGAAACGTATTCGCTTTGACCAAGACATCAAACCGTTATCTGAGTTTCGTTCAGGTGTGGCTTCGTTTATCAAACAAAT
CAATGAGACTCGGCGTCCGTTGGTGATTACTCAAAGGGGCAAGGGGGTTGCTGTGGTTCTGGATGTAGAAGAATATGAAG
CAATGCAAGAAAAAATAGAATTACTTGAAGAAATGCGAGCGGCAGAAGCACAACTTGCTTCAGGTATGGGAGTTTCCAAC
GAAGACGCTCGGGCTAATGTACTGGAACGTATTAAAAAATGA

Structures

Toxin

• AlphaFold DB: A0A1N6M071