Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3376120..3376667 Replicon chromosome
Accession NZ_AP024905
Organism Vibrio ruber strain LMG 23124

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCU42_RS14880 Protein ID WP_077335192.1
Coordinates 3376365..3376667 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCU42_RS14875 Protein ID WP_077335194.1
Coordinates 3376120..3376377 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU42_RS14850 3372275..3373264 + 990 WP_077335200.1 L-arabinose ABC transporter permease AraH -
OCU42_RS14855 3373433..3373711 - 279 Protein_2863 type II toxin-antitoxin system RelE/ParE family toxin -
OCU42_RS14860 3373708..3373905 - 198 Protein_2864 hypothetical protein -
OCU42_RS14865 3374184..3374870 + 687 WP_077335198.1 hypothetical protein -
OCU42_RS14870 3374980..3375978 + 999 WP_077335196.1 hypothetical protein -
OCU42_RS14875 3376120..3376377 + 258 WP_077335194.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU42_RS14880 3376365..3376667 + 303 WP_077335192.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU42_RS14885 3376770..3377723 + 954 WP_077335190.1 HEPN domain-containing protein -
OCU42_RS14890 3377927..3378322 - 396 WP_077335188.1 hypothetical protein -
OCU42_RS14895 3378324..3378980 - 657 WP_077335186.1 hypothetical protein -
OCU42_RS14900 3379019..3379516 - 498 WP_077335184.1 Hcp family type VI secretion system effector -
OCU42_RS14905 3379676..3380128 + 453 WP_077335182.1 hypothetical protein -
OCU42_RS14910 3380293..3380778 - 486 WP_205409440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11625.43 Da        Isoelectric Point: 4.8838

>T39826 WP_077335192.1 NZ_AP024905:3376365-3376667 [Vibrio ruber]
MAEIIWTESALSDLNDIAEYIALENVVAAQQLVHTLFSKVEHLENLPESGRVPPELEHLSYREIVVNPCRIFYKQDSDKV
FILLVMRAERDLRKFLLSKQ

Download         Length: 303 bp

>T39826 NZ_AP024905:3376365-3376667 [Vibrio ruber]
ATGGCTGAAATAATCTGGACGGAGTCAGCACTATCTGATCTTAATGACATCGCTGAATACATCGCACTTGAAAATGTTGT
CGCTGCACAGCAATTGGTTCACACGCTCTTCTCTAAAGTTGAACATCTGGAAAACCTCCCTGAATCGGGTCGCGTTCCGC
CCGAGCTAGAACATCTCAGTTATCGTGAAATTGTCGTTAATCCGTGTCGGATTTTCTATAAACAAGACAGCGACAAAGTC
TTTATTCTGTTAGTCATGCGCGCAGAGAGAGATTTGCGTAAGTTTCTATTGAGTAAGCAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9634.11 Da        Isoelectric Point: 6.7269

>AT39826 WP_077335194.1 NZ_AP024905:3376120-3376377 [Vibrio ruber]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEARDKM
SKWLK

Download         Length: 258 bp

>AT39826 NZ_AP024905:3376120-3376377 [Vibrio ruber]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACGAAGATCCTTGCCGATCTCCACGACACGAAAGAACCCGT
GTTGATTACTGAACACGGTAAGCCATCGGCATATCTGGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGCGA
TTCTGGAGGGGATTGCACGAGGTGAGCGCGCATTAGCTGATGGTAAAGTGGTGAGTCACGATGAAGCCAGGGACAAAATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References