Detailed information of TA system TA039823

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 236659..237181
• Replicon: chromosome
• Accession: NZ_AP024904
• Organism: Vibrio rhizosphaerae strain LMG 23790

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCV37_RS16260
• Protein ID: WP_038184256.1
• Coordinates: 236897..237181 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A1R4LGV6
• Locus tag: OCV37_RS16255
• Protein ID: WP_038184259.1
• Coordinates: 236659..236907 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCV37_RS16235	231817..232731	-	915	WP_211252081.1	homocysteine S-methyltransferase family protein	-
OCV37_RS16240	232971..233498	+	528	WP_038184261.1	PAS domain-containing protein	-
OCV37_RS16245	233506..234990	+	1485	WP_051680752.1	methyl-accepting chemotaxis protein	-
OCV37_RS16250	235131..236351	-	1221	WP_051680750.1	aldose 1-epimerase family protein	-
OCV37_RS16255	236659..236907	+	249	WP_038184259.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCV37_RS16260	236897..237181	+	285	WP_038184256.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCV37_RS16265	237308..238189	-	882	WP_038184253.1	HEPN domain-containing protein	-
OCV37_RS16270	238593..241658	-	3066	WP_038184251.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (12-72)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11170.18 Da
• Isoelectric Point: 10.6491

>T39823 WP_038184256.1 NZ_AP024904:236897-237181 [Vibrio rhizosphaerae]
MTYKLEFKKSALKEWEKLGSTLQQQFKKKLIERLENPYVPASKLSGADNMYKIKLRQSGYRIVYKVEDDIIIVTVLAVGK
RERNDVYRKAMKRR

Nucleotide

• Length: 285 bp

>T39823 NZ_AP024904:236897-237181 [Vibrio rhizosphaerae]
ATGACCTATAAACTTGAATTCAAAAAGAGTGCACTCAAAGAGTGGGAAAAGCTTGGTTCAACGCTGCAACAGCAATTTAA
GAAAAAGCTGATTGAGCGATTAGAGAACCCGTATGTGCCAGCCTCAAAACTTTCTGGTGCTGACAATATGTACAAAATAA
AATTGCGCCAATCGGGTTACCGCATAGTCTACAAAGTCGAAGACGATATCATTATTGTCACCGTCTTAGCCGTCGGCAAG
CGCGAGCGTAATGATGTTTACCGTAAGGCGATGAAACGGCGCTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9060.40 Da
• Isoelectric Point: 4.0653

>AT39823 WP_038184259.1 NZ_AP024904:236659-236907 [Vibrio rhizosphaerae]
MTSKILADVAASITELKANPMKVATSAYGEPVAVLNRNEPVFYCVPAEAYEMMMDKLEDLELLAIAKERESEESISVHID
DL

Nucleotide

• Length: 249 bp

>AT39823 NZ_AP024904:236659-236907 [Vibrio rhizosphaerae]
ATGACCTCTAAAATTTTGGCTGATGTTGCTGCCAGTATTACTGAGTTAAAAGCCAACCCGATGAAAGTTGCAACCAGTGC
TTACGGTGAACCGGTCGCTGTACTCAACCGAAATGAGCCAGTATTTTATTGCGTACCCGCTGAAGCGTACGAAATGATGA
TGGATAAACTCGAAGATCTTGAGCTACTTGCTATTGCGAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTTCATATTGAT
GACCTATAA

Structures

Antitoxin

• AlphaFold DB: A0A1R4LGV6