Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 96802..97565 Replicon chromosome
Accession NZ_AP024904
Organism Vibrio rhizosphaerae strain LMG 23790

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OCV37_RS15640 Protein ID WP_038181627.1
Coordinates 96802..97296 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OCV37_RS15645 Protein ID WP_038181625.1
Coordinates 97293..97565 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV37_RS15615 91920..92408 + 489 WP_038181696.1 hypothetical protein -
OCV37_RS15620 92614..93492 + 879 WP_261888158.1 HEPN domain-containing protein -
OCV37_RS15625 93857..94615 + 759 WP_038181634.1 alpha/beta hydrolase -
OCV37_RS15630 94827..96086 - 1260 WP_038181631.1 HipA domain-containing protein -
OCV37_RS15635 96073..96408 - 336 WP_038181630.1 helix-turn-helix transcriptional regulator -
OCV37_RS15640 96802..97296 - 495 WP_038181627.1 GNAT family N-acetyltransferase Toxin
OCV37_RS15645 97293..97565 - 273 WP_038181625.1 DUF1778 domain-containing protein Antitoxin
OCV37_RS15650 98219..99097 + 879 WP_261888159.1 HEPN domain-containing protein -
OCV37_RS15655 99729..100442 - 714 WP_038180117.1 class I SAM-dependent methyltransferase -
OCV37_RS15660 100673..101719 - 1047 WP_038180120.1 HipA domain-containing protein -
OCV37_RS15665 101703..102029 - 327 WP_038180122.1 HipA N-terminal domain-containing protein -
OCV37_RS15670 102014..102334 - 321 WP_038180123.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(85-159)

Antitoxin

Vibrio phage ICP1, Orf50

(3-89)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18373.93 Da        Isoelectric Point: 8.0586

>T39821 WP_038181627.1 NZ_AP024904:c97296-96802 [Vibrio rhizosphaerae]
MNTVLLDKSKHNRNRFDCGISALNNYLKVMASQQAKKDNTRTFILEDDNDESRIIGFYTLTMTPIDLNALPDKLQKKHHS
STSGGLIARLAVDANFQGKGFGEWLLIDALRKLLTASDTVAFPVVIVDAKDGAKHFYEQYGFTAFKDTENRLFITIADLR
ASLS

Download         Length: 495 bp

>T39821 NZ_AP024904:c97296-96802 [Vibrio rhizosphaerae]
ATGAATACGGTACTCCTTGATAAGTCTAAACATAACAGAAACCGATTCGACTGCGGTATCAGTGCTCTGAATAACTATCT
GAAAGTTATGGCGAGTCAGCAAGCAAAGAAAGATAACACCAGAACTTTTATTCTGGAAGATGATAACGATGAATCCAGAA
TTATTGGATTTTACACTTTAACCATGACGCCAATTGATCTAAATGCTTTACCAGATAAACTACAGAAAAAGCACCACTCA
TCAACGTCTGGCGGACTCATTGCTCGTTTAGCTGTTGATGCCAATTTTCAAGGGAAAGGTTTTGGCGAATGGTTATTGAT
CGACGCTCTTCGCAAACTACTGACTGCCAGTGATACTGTCGCGTTTCCTGTTGTTATCGTTGATGCAAAAGACGGCGCAA
AACACTTTTATGAACAATATGGGTTTACCGCATTTAAAGATACAGAAAACCGACTATTTATCACGATTGCTGATCTTCGA
GCCAGCCTGAGCTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9778.26 Da        Isoelectric Point: 5.0651

>AT39821 WP_038181625.1 NZ_AP024904:c97565-97293 [Vibrio rhizosphaerae]
MATLPRITARVDVETQDLLAKAAAIAGMPSINSFVLSAATEKAMQVIEREETLKLSQADAMLLMDALDRPATSNAKLKTA
AQRYEDKTQQ

Download         Length: 273 bp

>AT39821 NZ_AP024904:c97565-97293 [Vibrio rhizosphaerae]
ATGGCAACACTACCTCGCATCACTGCCCGAGTCGATGTTGAAACACAAGACTTACTGGCTAAAGCTGCTGCTATTGCCGG
TATGCCGAGTATTAATTCATTCGTTCTCAGCGCCGCTACTGAAAAAGCAATGCAAGTTATCGAACGCGAAGAAACACTAA
AGCTTAGCCAAGCTGACGCTATGTTATTGATGGATGCACTCGACCGTCCGGCTACATCAAATGCAAAACTGAAAACTGCG
GCTCAACGTTATGAAGATAAGACTCAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References