Detailed information of TA system TA039819

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 3407266..3407813
• Replicon: chromosome
• Accession: NZ_AP024903
• Organism: Vibrio rhizosphaerae strain LMG 23790

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OCV37_RS14825
• Protein ID: WP_038185390.1
• Coordinates: 3407511..3407813 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OCV37_RS14820
• Protein ID: WP_038185391.1
• Coordinates: 3407266..3407523 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCV37_RS14805	3403541..3404545	+	1005	WP_038185398.1	arabinose ABC transporter substrate-binding protein	-
OCV37_RS14810	3404600..3406117	+	1518	WP_038185397.1	L-arabinose ABC transporter ATP-binding protein AraG	-
OCV37_RS14815	3406130..3407119	+	990	WP_038185393.1	L-arabinose ABC transporter permease AraH	-
OCV37_RS14820	3407266..3407523	+	258	WP_038185391.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OCV37_RS14825	3407511..3407813	+	303	WP_038185390.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OCV37_RS14830	3407985..3408881	+	897	WP_038185575.1	HEPN domain-containing protein	-
OCV37_RS14835	3409073..3409468	-	396	WP_038185387.1	hypothetical protein	-
OCV37_RS14840	3409695..3410180	-	486	WP_211252103.1	hypothetical protein	-
OCV37_RS14845	3410298..3411176	-	879	WP_038185384.1	LysR substrate-binding domain-containing protein	-
OCV37_RS14850	3411319..3412539	+	1221	WP_038185381.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11655.51 Da
• Isoelectric Point: 4.8838

>T39819 WP_038185390.1 NZ_AP024903:3407511-3407813 [Vibrio rhizosphaerae]
MAEIIWTESALSDLNDIAEYIALENVVAAQQLVHMLFSKVEHLENLPESGRVPPELEHLSYREIVVNPCRIFYKQDSDKV
FILLVMRAERDLRKFLLSKQ

Nucleotide

• Length: 303 bp

>T39819 NZ_AP024903:3407511-3407813 [Vibrio rhizosphaerae]
ATGGCTGAAATAATCTGGACGGAGTCAGCACTATCTGATCTTAATGACATCGCTGAATACATCGCACTTGAAAATGTTGT
CGCTGCACAGCAATTGGTTCACATGCTCTTCTCTAAAGTTGAACATCTGGAAAACCTCCCTGAATCGGGTCGCGTTCCGC
CCGAGCTAGAACATCTCAGTTATCGTGAAATTGTCGTTAATCCGTGTCGGATTTTCTATAAACAAGACAGCGACAAAGTC
TTTATTCTGTTAGTCATGCGCGCAGAGAGAGATTTGCGTAAGTTTCTATTGAGTAAGCAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9698.23 Da
• Isoelectric Point: 6.7269

>AT39819 WP_038185391.1 NZ_AP024903:3407266-3407523 [Vibrio rhizosphaerae]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKMMSHDEARDKM
SKWLK

Nucleotide

• Length: 258 bp

>AT39819 NZ_AP024903:3407266-3407523 [Vibrio rhizosphaerae]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACGAAGATCCTTGCCGATCTCCACGACACGAAAGAACCCGT
GTTGATTACTGAACACGGTAAGCCATCGGCATATCTGGTTGATGTTGATGATTACGAGTTTATGCAAAATCGTTTGGCGA
TTCTGGAGGGGATTGCACGAGGTGAGCGCGCATTAGCTGATGGTAAAATGATGAGTCACGATGAAGCCAGGGACAAAATG
TCAAAATGGCTGAAATAA