39818

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YefM(antitoxin)
Location 1923070..1923638 Replicon chromosome
Accession NZ_AP024903
Organism Vibrio rhizosphaerae strain LMG 23790

Toxin (Protein)


Gene name relE Uniprot ID A0A1N6M071
Locus tag OCV37_RS08190 Protein ID WP_038179721.1
Coordinates 1923070..1923360 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7D7X6I1
Locus tag OCV37_RS08195 Protein ID WP_038179832.1
Coordinates 1923357..1923638 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV37_RS08175 1919171..1919725 - 555 WP_038179725.1 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase -
OCV37_RS08180 1920275..1921009 - 735 WP_038179833.1 SLATT domain-containing protein -
OCV37_RS08185 1921202..1922176 - 975 WP_038179723.1 hypothetical protein -
OCV37_RS08190 1923070..1923360 - 291 WP_038179721.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCV37_RS08195 1923357..1923638 - 282 WP_038179832.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCV37_RS08200 1924237..1925115 - 879 WP_261888068.1 HEPN domain-containing protein -
OCV37_RS08205 1925327..1925563 - 237 WP_038179717.1 hypothetical protein -
OCV37_RS08210 1925565..1927064 - 1500 WP_038179715.1 S-type pyocin domain-containing protein -
OCV37_RS08215 1927989..1928252 - 264 WP_038179713.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-76)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11004.68 Da        Isoelectric Point: 4.3313

>T39818 WP_038179721.1 NZ_AP024903:c1923360-1923070 [Vibrio rhizosphaerae]
MNVVWAPFALEKLGDAAEFISLDDPVAAENWVNDVFDKTELLGTMPEMGRVVPELPNTNYREIIFGHYRIIYSCSIEIRI
LTVRNCRQILTKDDVC

Download         Length: 291 bp

>T39818 NZ_AP024903:c1923360-1923070 [Vibrio rhizosphaerae]
ATGAATGTTGTTTGGGCGCCATTCGCCCTTGAGAAATTAGGAGATGCGGCAGAATTTATTTCGTTAGACGATCCTGTAGC
AGCAGAAAATTGGGTTAATGATGTTTTTGATAAAACGGAATTATTAGGAACTATGCCTGAAATGGGGAGAGTTGTTCCCG
AGCTGCCGAATACGAACTATCGAGAAATTATCTTTGGTCACTACCGTATTATTTATAGTTGCTCTATTGAAATACGGATA
CTCACAGTGAGAAATTGCCGTCAGATATTAACAAAAGATGACGTATGCTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10591.23 Da        Isoelectric Point: 6.3999

>AT39818 WP_038179832.1 NZ_AP024903:c1923638-1923357 [Vibrio rhizosphaerae]
MKRIRFDQDIKPLSEFRSGVASFIKQINETRRPLVITQRGKGVAVVLDVEEYEAMQEKIELLEEMRAAEAQLASGMGISN
EDARANVLERIKK

Download         Length: 282 bp

>AT39818 NZ_AP024903:c1923638-1923357 [Vibrio rhizosphaerae]
ATGAAACGTATTCGCTTTGACCAAGACATCAAACCGTTATCTGAATTTCGTTCAGGTGTGGCTTCGTTTATCAAACAAAT
CAATGAGACTCGGCGTCCGTTGGTGATTACTCAAAGGGGCAAGGGGGTTGCTGTGGTTCTGGATGTAGAAGAATATGAAG
CAATGCAAGAAAAAATAGAATTACTTGAAGAAATGCGAGCGGCAGAAGCACAACTTGCTTCAGGTATGGGAATTTCTAAC
GAAGACGCTCGGGCTAATGTACTGGAACGTATTAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1N6M071

Antitoxin

Source ID Structure
AlphaFold DB A0A7D7X6I1

References