Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 576484..577250 Replicon chromosome
Accession NZ_AP024901
Organism Vibrio rarus strain LMG 23674

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OCU56_RS15630 Protein ID WP_261874880.1
Coordinates 576484..576981 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OCU56_RS15635 Protein ID WP_261874881.1
Coordinates 576978..577250 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU56_RS15595 571594..572493 + 900 Protein_509 IS5 family transposase -
OCU56_RS15600 572627..573295 - 669 WP_261874876.1 hypothetical protein -
OCU56_RS15605 573295..574233 - 939 WP_261874877.1 hypothetical protein -
OCU56_RS15610 574283..575050 - 768 WP_261874878.1 hypothetical protein -
OCU56_RS15615 575344..575610 - 267 Protein_513 GNAT family N-acetyltransferase -
OCU56_RS15620 575871..576176 + 306 WP_141346783.1 helix-turn-helix domain-containing protein -
OCU56_RS15625 576173..576469 + 297 WP_261874879.1 hypothetical protein -
OCU56_RS15630 576484..576981 - 498 WP_261874880.1 GNAT family N-acetyltransferase Toxin
OCU56_RS15635 576978..577250 - 273 WP_261874881.1 DUF1778 domain-containing protein Antitoxin
OCU56_RS15640 577668..579245 + 1578 WP_261874882.1 site-specific integrase -
OCU56_RS15645 579235..582138 + 2904 WP_261874883.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 559807..586135 26328


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-151)

Antitoxin

Vibrio phage ICP1, Orf50

(7-85)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18676.16 Da        Isoelectric Point: 6.8735

>T39816 WP_261874880.1 NZ_AP024901:c576981-576484 [Vibrio rarus]
MMNSVLLDKAKHDRNRFNCGIDELNNYLKVMASQQAKKDNTRTFVLEDDRNNSHIIGFYTLTMTPIDLKALPDRLQEKHH
SSTSGGLIARLAVDNRYQARGFGEWLLIDALRKLVAASDSVAFPVVIVDAKDGAKDFYERYGFQAFSDTENKLFITISDV
RESLG

Download         Length: 498 bp

>T39816 NZ_AP024901:c576981-576484 [Vibrio rarus]
ATGATGAACTCGGTGCTTCTCGATAAAGCTAAACACGATAGAAACCGGTTCAACTGTGGTATCGATGAGCTAAATAACTA
TTTAAAGGTGATGGCGAGTCAACAAGCAAAAAAAGACAATACTAGAACTTTCGTATTGGAAGATGATAGAAACAATTCAC
ATATCATCGGCTTTTATACACTCACAATGACACCAATTGACTTAAAGGCATTACCCGATAGGCTACAAGAAAAGCACCAT
TCTTCGACATCGGGTGGCCTTATCGCTCGCCTGGCTGTTGACAATCGATATCAAGCGAGAGGTTTTGGTGAGTGGTTACT
TATTGATGCACTAAGAAAGCTGGTAGCTGCGAGCGACAGCGTTGCGTTTCCAGTCGTGATTGTTGATGCTAAAGATGGTG
CAAAAGACTTTTATGAAAGATATGGATTTCAGGCGTTTAGTGATACAGAAAATAAGCTTTTTATTACTATCTCAGATGTT
AGAGAAAGCTTAGGTTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9734.24 Da        Isoelectric Point: 9.7672

>AT39816 WP_261874881.1 NZ_AP024901:c577250-576978 [Vibrio rarus]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQADAMLLMDALDRPAKSNAKLKA
ASDRYENKTQ

Download         Length: 273 bp

>AT39816 NZ_AP024901:c577250-576978 [Vibrio rarus]
ATGGCCACTACTTTACCTCGTATTACTGCTCGGGTGGATGTCGATACCCAAGACTTGCTGACCAAGGCTGCGGCAATAGC
CGGTATGTCCAGTATCAACTCTTTTGTATTGAGTGCGGCAATTGAAAAAGCCAAACAAGTGATTGAGCGTGAGCAGGCTT
TAAAATTGAGTCAGGCTGACGCGATGCTGTTGATGGATGCCCTAGATCGTCCAGCTAAATCGAATGCCAAATTGAAAGCA
GCGTCTGATCGGTACGAGAATAAAACACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References