Detailed information of TA system TA039814

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 550229..550992
• Replicon: chromosome
• Accession: NZ_AP024901
• Organism: Vibrio rarus strain LMG 23674

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: OCU56_RS15460
• Protein ID: WP_261874859.1
• Coordinates: 550229..550735 (-)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: OCU56_RS15465
• Protein ID: WP_261874860.1
• Coordinates: 550726..550992 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCU56_RS15440	546411..546554	-	144	WP_261874856.1	hypothetical protein	-
OCU56_RS15445	547319..548911	-	1593	WP_261874857.1	alkyl hydroperoxide reductase subunit F	-
OCU56_RS15450	549124..549681	-	558	WP_261874858.1	alkyl hydroperoxide reductase subunit C	-
OCU56_RS15455	549800..550045	-	246	Protein_481	type II toxin-antitoxin system RelE/ParE family toxin	-
OCU56_RS15460	550229..550735	-	507	WP_261874859.1	GNAT family N-acetyltransferase	Toxin
OCU56_RS15465	550726..550992	-	267	WP_261874860.1	DUF1778 domain-containing protein	Antitoxin
OCU56_RS15470	551257..551440	-	184	Protein_484	type II toxin-antitoxin system YoeB family toxin	-
OCU56_RS15475	551433..551617	-	185	Protein_485	type II toxin-antitoxin system Phd/YefM family antitoxin	-
OCU56_RS15480	551618..552919	-	1302	WP_261874861.1	type II toxin-antitoxin system HipA family toxin	-
OCU56_RS15485	552919..553164	-	246	WP_261874862.1	type II toxin-antitoxin system antitoxin HipB	-
OCU56_RS15490	553667..554104	-	438	WP_261874863.1	helix-turn-helix domain-containing protein	-
OCU56_RS15495	554115..554327	-	213	WP_261874864.1	DUF4258 domain-containing protein	-
OCU56_RS15500	554657..554758	+	102	WP_261875584.1	transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (49-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (2-88)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18288.13 Da
• Isoelectric Point: 8.6896

>T39814 WP_261874859.1 NZ_AP024901:c550735-550229 [Vibrio rarus]
MGISAPTLLTNDHKISAFQCGIEELDIWLRKQALKNQKRGTARVYAVNNTDTHQVVGYYAIAIGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDSGAQMFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Nucleotide

• Length: 507 bp

>T39814 NZ_AP024901:c550735-550229 [Vibrio rarus]
TTGGGAATAAGTGCACCAACCCTGCTCACTAATGATCACAAGATTAGTGCCTTTCAATGTGGCATCGAAGAACTCGATAT
TTGGTTAAGAAAACAGGCTTTAAAGAATCAAAAGCGGGGAACCGCGAGGGTGTATGCTGTCAATAACACTGATACCCATC
AAGTTGTTGGGTATTATGCCATTGCCATTGGCTCTGTTTCCAGAGAGCAAGCATTTAGTTCACTACGGAGAAATAGCCCT
GATCCCATTCCCATGGTGATTCTAGCCCGGCTTGGGGTAGATAATGCCTATCAAGGTCAAGGCATTGCAGCGGGTCTTTT
AAAAGATTGTATCATTCGATCAGTACAAGCAATGAACGCTGTCGGTGGGGCAGGAATCTTAGTCCATGCTATTGATAGTG
GTGCGCAAATGTTCTACAAGAAATTTGGCTTTAAAGAATCGACATTTGATCCTTTAGTACTTATGGCAAGGATCTGCGAT
ATCGAAAAATCATTGTCAATAGACTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9880.32 Da
• Isoelectric Point: 5.7066

>AT39814 WP_261874860.1 NZ_AP024901:c550992-550726 [Vibrio rarus]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSVLAEHRDFVLEAKAFEAFDNELSAEPQTLEGIKDL
FKRKSPWE

Nucleotide

• Length: 267 bp

>AT39814 NZ_AP024901:c550992-550726 [Vibrio rarus]
ATGGCAACAAAAACAGCGCCAATCAACATGCGAGTATTACCATCGGTAAGAGACATTATCGATGCCGCTGCAAGTTTAAA
AAAAGTCGATAGAACCGTGTTCATTCAACAAGCCGCTCTCAATGAAGCCCATAGCGTACTGGCAGAACATCGGGATTTTG
TTCTTGAAGCAAAGGCTTTTGAAGCATTCGATAACGAACTTAGCGCAGAACCACAGACTCTTGAAGGCATTAAAGACCTG
TTTAAAAGGAAATCGCCTTGGGAATAA