Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 144678..145543 Replicon chromosome
Accession NZ_AP024901
Organism Vibrio rarus strain LMG 23674

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OCU56_RS13695 Protein ID WP_261875297.1
Coordinates 145013..145543 (+) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OCU56_RS13690 Protein ID WP_261875614.1
Coordinates 144678..145016 (+) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU56_RS13675 140619..142427 - 1809 WP_261875294.1 extracellular solute-binding protein -
OCU56_RS13680 142724..143083 - 360 WP_261875295.1 glutaredoxin domain-containing protein -
OCU56_RS13685 143658..144374 + 717 WP_261875296.1 hypothetical protein -
OCU56_RS13690 144678..145016 + 339 WP_261875614.1 DUF1778 domain-containing protein Antitoxin
OCU56_RS13695 145013..145543 + 531 WP_261875297.1 GNAT family N-acetyltransferase Toxin
OCU56_RS13700 146058..148265 - 2208 WP_261875298.1 NERD domain-containing protein -
OCU56_RS13705 148716..149306 + 591 WP_261875299.1 class I tRNA ligase family protein -
OCU56_RS13710 149298..150038 - 741 WP_068699098.1 IS21-like element ISVch3 family helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(28-103)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19899.16 Da        Isoelectric Point: 8.7689

>T39813 WP_261875297.1 NZ_AP024901:145013-145543 [Vibrio rarus]
VSYSKTFKELDKSQHDRASFDCGEKELNDFIQTQAAKHMQAGISRTMVLPASVPLPNQKYPICSFYSIAPSSISRDTLPQ
AMAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIKALEYLWEINSHMRAYAIVVDCLTEQAESFYAKYGFEILCEING
RLRMFIPMKTVGQLFT

Download         Length: 531 bp

>T39813 NZ_AP024901:145013-145543 [Vibrio rarus]
GTGAGTTATTCCAAAACTTTCAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGGGAAAAAGAGTT
AAATGATTTTATCCAAACTCAAGCTGCTAAACATATGCAAGCAGGTATAAGTCGTACAATGGTTTTGCCTGCTTCTGTGC
CATTACCCAATCAAAAATATCCAATTTGTTCATTTTATAGTATTGCGCCAAGTTCGATTAGCCGTGATACGTTGCCACAA
GCGATGGCTAAAAAATTACCGCGCTATCCAATACCTGTTTTCCTTTTAGCTCAATTGGCAGTTCATAAAGAATTTCATGG
CAGCGGATTAGGTAAAGTTAGCTTAATCAAAGCTCTCGAATATCTTTGGGAAATTAACTCTCACATGAGAGCTTATGCCA
TTGTTGTTGATTGTTTAACTGAACAAGCTGAGTCATTTTACGCAAAATATGGTTTCGAGATTCTTTGCGAAATCAACGGT
CGTCTAAGAATGTTCATTCCGATGAAAACAGTCGGTCAGTTATTCACTTAG

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12387.24 Da        Isoelectric Point: 4.6168

>AT39813 WP_261875614.1 NZ_AP024901:144678-145016 [Vibrio rarus]
MRFDGLNFILRLIAESLRTIGGFMATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVISEHEGITVEAN
VFDQFMAACDEAKAPNKALLEATAFTKSGEFK

Download         Length: 339 bp

>AT39813 NZ_AP024901:144678-145016 [Vibrio rarus]
TTGCGCTTTGATGGTTTGAATTTTATACTCAGGTTGATTGCGGAATCACTCCGTACAATTGGAGGTTTTATGGCTACTGC
AAGACTTGATATCCGTTTGGATGAAGAAATCAAAGCTAAGGCTGAGAAAGCATCAGCTTTACTTGGTTTAAAAAGCTTAA
CTGAATACGTTGTTCGTTTAATGGACGAAGATTCAACTCAGGTGATTTCTGAGCATGAAGGTATCACTGTTGAAGCAAAT
GTATTTGATCAATTCATGGCTGCTTGTGACGAGGCTAAGGCTCCGAATAAAGCATTACTTGAAGCAACTGCATTTACTAA
AAGTGGTGAGTTTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References