Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1541307..1541854 Replicon chromosome
Accession NZ_AP024900
Organism Vibrio rarus strain LMG 23674

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCU56_RS07180 Protein ID WP_261872551.1
Coordinates 1541307..1541609 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCU56_RS07185 Protein ID WP_261872552.1
Coordinates 1541597..1541854 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU56_RS07150 1537993..1538271 + 279 WP_261872545.1 50S ribosomal protein L25 -
OCU56_RS07155 1538504..1538698 - 195 WP_261872546.1 hypothetical protein -
OCU56_RS07160 1538798..1539334 - 537 WP_261872547.1 nucleotidyltransferase family protein -
OCU56_RS07165 1539470..1540366 - 897 WP_261872548.1 hypothetical protein -
OCU56_RS07170 1540601..1540843 + 243 WP_261872549.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OCU56_RS07175 1540852..1541151 + 300 WP_261872550.1 type II toxin-antitoxin system RelE/ParE family toxin -
OCU56_RS07180 1541307..1541609 - 303 WP_261872551.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU56_RS07185 1541597..1541854 - 258 WP_261872552.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU56_RS07190 1542569..1542826 - 258 WP_261872553.1 DUF1289 domain-containing protein -
OCU56_RS07195 1542984..1543466 + 483 WP_261872554.1 META domain-containing protein -
OCU56_RS07200 1543486..1543875 - 390 WP_261872555.1 hypothetical protein -
OCU56_RS07205 1544334..1546022 + 1689 WP_261872556.1 NAD-dependent malic enzyme -
OCU56_RS07210 1546172..1546813 + 642 WP_261872557.1 ElyC/SanA/YdcF family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11704.64 Da        Isoelectric Point: 4.8779

>T39812 WP_261872551.1 NZ_AP024900:c1541609-1541307 [Vibrio rarus]
MAEIIWTAPALSDLNDIAEYIALENMVAAKLLVKSVFDKVDRLEMFPESGRIPPELDYLNYREVVASPCRVFYKQGNDKV
YILYVMREERDLRKFLLSKQ

Download         Length: 303 bp

>T39812 NZ_AP024900:c1541609-1541307 [Vibrio rarus]
ATGGCTGAAATAATCTGGACAGCTCCTGCCTTATCAGATCTAAATGACATTGCTGAATACATAGCGTTAGAAAATATGGT
TGCGGCTAAACTGTTAGTTAAATCAGTTTTTGACAAAGTGGATCGTTTAGAAATGTTCCCTGAATCGGGACGTATTCCAC
CCGAACTTGACTATTTAAACTACCGTGAAGTTGTTGCTAGCCCTTGCCGTGTTTTCTACAAACAAGGCAATGACAAGGTT
TACATTTTGTATGTGATGCGAGAAGAACGAGATCTACGTAAATTTTTGCTGAGTAAACAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9586.07 Da        Isoelectric Point: 8.5625

>AT39812 WP_261872552.1 NZ_AP024900:c1541854-1541597 [Vibrio rarus]
MKVELVTSLKRQATKILSDLHHSKEPVLITEHGKPSAYLVDVDDYESMQNRLSILEGIARGERAIADGKIISHSEAKDKM
SKWLK

Download         Length: 258 bp

>AT39812 NZ_AP024900:c1541854-1541597 [Vibrio rarus]
ATGAAAGTTGAACTTGTCACATCCTTGAAACGTCAGGCTACAAAAATCTTATCGGATCTTCATCATAGTAAAGAGCCAGT
GTTGATTACCGAGCATGGTAAGCCATCAGCTTATCTAGTTGATGTTGATGACTATGAGTCTATGCAGAATCGTCTTTCTA
TCCTTGAAGGTATCGCTAGAGGTGAACGTGCAATCGCTGATGGTAAGATTATTTCTCATAGTGAAGCGAAAGATAAGATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References