Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1540601..1541151 Replicon chromosome
Accession NZ_AP024900
Organism Vibrio rarus strain LMG 23674

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OCU56_RS07175 Protein ID WP_261872550.1
Coordinates 1540852..1541151 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OCU56_RS07170 Protein ID WP_261872549.1
Coordinates 1540601..1540843 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU56_RS07145 1536079..1537815 + 1737 WP_261872544.1 DEAD/DEAH box helicase -
OCU56_RS07150 1537993..1538271 + 279 WP_261872545.1 50S ribosomal protein L25 -
OCU56_RS07155 1538504..1538698 - 195 WP_261872546.1 hypothetical protein -
OCU56_RS07160 1538798..1539334 - 537 WP_261872547.1 nucleotidyltransferase family protein -
OCU56_RS07165 1539470..1540366 - 897 WP_261872548.1 hypothetical protein -
OCU56_RS07170 1540601..1540843 + 243 WP_261872549.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU56_RS07175 1540852..1541151 + 300 WP_261872550.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU56_RS07180 1541307..1541609 - 303 WP_261872551.1 type II toxin-antitoxin system RelE/ParE family toxin -
OCU56_RS07185 1541597..1541854 - 258 WP_261872552.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OCU56_RS07190 1542569..1542826 - 258 WP_261872553.1 DUF1289 domain-containing protein -
OCU56_RS07195 1542984..1543466 + 483 WP_261872554.1 META domain-containing protein -
OCU56_RS07200 1543486..1543875 - 390 WP_261872555.1 hypothetical protein -
OCU56_RS07205 1544334..1546022 + 1689 WP_261872556.1 NAD-dependent malic enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-49)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11364.03 Da        Isoelectric Point: 9.8645

>T39811 WP_261872550.1 NZ_AP024900:1540852-1541151 [Vibrio rarus]
MRTNKYKLSKLAQSHLRKIKSYTVTNFSELQWSSYRDNLLTAFQMLADNPAVGRSCDELYPSGFYFPVGKHTAYFTKEDG
FILIVAVLGQSQLPQNHLK

Download         Length: 300 bp

>T39811 NZ_AP024900:1540852-1541151 [Vibrio rarus]
ATGCGAACGAATAAATATAAGCTAAGTAAATTGGCGCAAAGCCATTTGCGTAAAATTAAAAGCTACACAGTTACAAACTT
TTCCGAATTACAATGGAGTAGCTACAGAGACAACCTACTTACTGCTTTTCAAATGCTTGCTGACAATCCAGCAGTTGGTA
GAAGCTGTGATGAGTTGTACCCAAGCGGCTTCTACTTCCCTGTTGGCAAGCACACTGCCTACTTTACCAAAGAAGACGGC
TTTATTCTGATCGTTGCTGTTCTTGGTCAATCGCAGCTACCTCAGAATCATTTGAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8986.26 Da        Isoelectric Point: 5.6851

>AT39811 WP_261872549.1 NZ_AP024900:1540601-1540843 [Vibrio rarus]
MHTLTANDAKRNFGELLLRAQREPVKISKNSKDAVVVMSIQDYEELEAMKADYIKHCFEAAKVDLAQGNTVDGETFLKSL

Download         Length: 243 bp

>AT39811 NZ_AP024900:1540601-1540843 [Vibrio rarus]
ATGCATACATTAACAGCAAATGACGCTAAACGTAATTTTGGCGAACTACTTCTAAGGGCTCAACGAGAACCTGTTAAAAT
TAGTAAAAACAGCAAAGATGCGGTCGTTGTAATGTCCATTCAAGACTACGAAGAACTTGAAGCAATGAAAGCTGATTACA
TTAAACATTGCTTTGAGGCTGCAAAAGTCGACCTAGCACAAGGTAATACAGTTGATGGCGAAACATTCTTGAAGAGCCTG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References